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Author Details

Michael Chang
Columbia University Medical Center
2001
35
17
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36947417Deletion of MEC1 suppresses the replicative senescence of the cdc13-2 mutant in Saccharomyces cerevisiae.G3 (Bethesda)2023
34751785Suppression of cdc13-2-associated senescence by pif1-m2 requires Ku-mediated telomerase recruitment.G3 (Bethesda)2022
35795254Investigating the role of G-quadruplexes at <i>Saccharomyces cerevisiae</i> telomeres.Microb Cell2022
35059655High-throughput replica-pinning approach to screen for yeast genes controlling low-frequency events.STAR Protoc2022
34550356A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers.G3 (Bethesda)2021
32265288A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in <i>Saccharomyces cerevisiae</i>.G3 (Bethesda)2020
31854076A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells.Aging Cell2020
29052759Telomerase regulation by the Pif1 helicase: a length-dependent effect?Curr Genet2018
29848621Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in <i>Saccharomyces cerevisiae</i>.G3 (Bethesda)2018
29354647Guidelines and recommendations on yeast cell death nomenclature.Microb Cell2018
28685142A simple microfluidic platform to study age-dependent protein abundance and localization changes in <i>Saccharomyces cerevisiae</i>.Microb Cell2017
28384494Increased genome instability is not accompanied by sensitivity to DNA damaging agents in aged yeast cells.DNA Repair (Amst)2017
29231811Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq.Elife2017
28724919Generally Applicable Transformation Protocols for Fluorescent Nanodiamond Internalization into Cells.Sci Rep2017
28826474A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres.Elife2017
26974669Recombination-Mediated Telomere Maintenance in Saccharomyces cerevisiae Is Not Dependent on the Shu Complex.PLoS One2016
27428329Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Prevent Telomere Attrition-Induced Senescence in Saccharomyces cerevisiae.PLoS Genet2016
28357308The many facets of homologous recombination at telomeres.Microb Cell2015
23335335Telomere length homeostasis responds to changes in intracellular dNTP pools.Genetics2013
23028367Rif2 promotes a telomere fold-back structure through Rpd3L recruitment in budding yeast.PLoS Genet2012
25436544Long telomeres: too much of a good thing.Biomol Concepts2012
21441915Long telomeres are preferentially extended during recombination-mediated telomere maintenance.Nat Struct Mol Biol2011
22033189Rif1/2 and Tel1 function in separate pathways during replicative senescence.Cell Cycle2011
19704012Telomerase is essential to alleviate pif1-induced replication stress at telomeres.Genetics2009
18388281Cell signaling. Tel2 finally tells one story.Science2008
17908934Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae.Genes Dev2007
16537486BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates.Proc Natl Acad Sci U S A2006
16793404Genomic approaches for identifying DNA damage response pathways in S. cerevisiae.Methods Enzymol2006
15889139RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex.EMBO J2005
14764870Global mapping of the yeast genetic interaction network.Science2004
15238513The origin recognition complex links replication, sister chromatid cohesion and transcriptional silencing in Saccharomyces cerevisiae.Genetics2004
14742714Identification of protein complexes required for efficient sister chromatid cohesion.Mol Biol Cell2004
12912927Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.EMBO J2003
12482937A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage.Proc Natl Acad Sci U S A2002
11533240Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4.Mol Cell Biol2001
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Collaborators

Grant W Brown
University of Toronto, 1 King's College Circle
Co-authored papers 9
Charles Boone
University of Toronto
Co-authored papers 7
Rodney Rothstein
Columbia University Vagelos College of Physicians & Surgeons
Co-authored papers 7
Hong Xu
British Columbia Cancer Research Centre
Co-authored papers 3
Liesbeth M Veenhoff
European Institute for the Biology of Ageing, University of Groningen
Co-authored papers 3
Jennifer Haynes
Joan C. Edwards School of Medicine, Marshall University
Co-authored papers 2
Bernhard Suter
Baylor College of Medicine
Co-authored papers 2
Zhijian Li
University of Toronto
Co-authored papers 2
Bilal N Sheikh
Helmholtz Institute for Metabolic
Co-authored papers 2
Amy Hin Yan Tong
University of Toronto
Co-authored papers 2
Matthias Peter
Institute of Biochemistry, ETH Zurich
Co-authored papers 2
Sushma Sharma
Umea University
Co-authored papers 2
Ainslie B Parsons
University of Toronto
Co-authored papers 2
Brenda J Andrews
University of Toronto
Co-authored papers 2
Jasper Rine
University of California berkeley
Co-authored papers 2
Andrei Chabes
Umea University
Co-authored papers 2
Jason Moffat
University of Toronto
Co-authored papers 1
Joshua N Levinson
MedStar Washington Hospital Center
Co-authored papers 1
Patrice Menard
Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark
Co-authored papers 1
Guillaume Lesage
Institute of Molecular Biology, University of Zurich
Co-authored papers 1
Chris Sander
Broad Institute of MIT and Harvard
Co-authored papers 1
Grace He
Co-authored papers 1
Xin Cheng
New York University School of Medicine
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Lan V Zhang
Harvard Medical School
Co-authored papers 1
Christine Humphries
University of Toronto
Co-authored papers 1
Anne-Marie Sdicu
McGill University
Co-authored papers 1
Richard Y Zhao
University of Maryland School of Medicine
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Gabriel F Berriz
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