Author details

Full Name

Audrey Y Chu

Affiliation

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36048866	Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk.	Hum Mol Genet	2023
34426670	Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits.	Nat Hum Behav	2022
35697829	Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.	Commun Biol	2022
36055212	Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies.	Am J Hum Genet	2022
33137338	Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.	Kidney Int	2021
31197173	An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.	Nat Commun	2019
30232418	Integrating genetic, transcriptional, and biological information provides insights into obesity.	Int J Obes (Lond)	2019
29988085	Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.	Mol Psychiatry	2019
31070471	Group IIA Secretory Phospholipase A<sub>2</sub>, Vascular Inflammation, and Incident Cardiovascular Disease.	Arterioscler Thromb Vasc Biol	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
31345923	Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis.	BMJ	2019
31152163	A catalog of genetic loci associated with kidney function from analyses of a million individuals.	Nat Genet	2019
29273807	Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
30315176	Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels.	Nat Commun	2018
29549330	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29549329	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018
28146470	Rare and low-frequency coding variants alter human adult height.	Nature	2017
28733430	Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low-Density Lipoprotein Cholesterol.	J Am Heart Assoc	2017
28548086	Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Sci Rep	2017
28341696	A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.	Diabetes	2017
28898252	Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.	PLoS Med	2017
28452372	1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.	Sci Rep	2017
28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	PLoS Genet	2017
28614350	Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions.	PLoS Genet	2017
28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Nat Commun	2017
28832619	Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	PLoS Genet	2017
29097680	Epigenome-wide association studies identify DNA methylation associated with kidney function.	Nat Commun	2017
29083408	Exome-wide association study of plasma lipids in >300,000 individuals.	Nat Genet	2017
29236708	Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts.	PLoS One	2017
28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Am J Hum Genet	2017
27920155	<i>SOS2</i> and <i>ACP1</i> Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.	J Am Soc Nephrol	2017
27918534	Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.	Nat Genet	2017
28103844	Genetic risk score and risk of stage 3 chronic kidney disease.	BMC Nephrol	2017
27876822	A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.	Nat Commun	2016
27252175	A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.	Sci Transl Med	2016
26791180	Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.	Am J Clin Nutr	2016
26831199	Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.	Nat Commun	2016
26822414	A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans.	BMC Endocr Disord	2016
27261331	Dietary Guideline Adherence Index and Kidney Measures inÂ theÂ Framingham Heart Study.	Am J Kidney Dis	2016
26006263	Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans.	Schizophr Bull	2016
26631737	Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.	Diabetes	2016
27955697	DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.	Genome Biol	2016
27618448	Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.	Nat Genet	2016
25998023	Lifestyle factors and indices of kidney function in the Framingham Heart Study.	Am J Nephrol	2015
25378659	Genetic loci associated with circulating levels of very long-chain saturated fatty acids.	J Lipid Res	2015
25631608	Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.	Nat Commun	2015
25626431	Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium.	Mol Nutr Food Res	2015
25493955	Genome-wide association study of kidney function decline in individuals of European descent.	Kidney Int	2015
25646338	Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.	Am J Clin Nutr	2015