Author details

Full Name

Joshua C Bis

Affiliation

ORCID

Career Start Year

2002

Papers

294

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37961373	Frequency of Variants in Mendelian Alzheimer's Disease Genes within the Alzheimer's Disease Sequencing Project (ADSP).	medRxiv	2024
36670186	Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes.	Commun Med (Lond)	2023
35943854	Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI.	Brain	2023
37745480	Whole Genome Sequencing Based Analysis of Inflammation Biomarkers in the Trans-Omics for Precision Medicine (TOPMed) Consortium.	bioRxiv	2023
37662265	WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.	medRxiv	2023
37923804	Identification of circulating proteins associated with general cognitive function among middle-aged and older adults.	Commun Biol	2023
38007645	Proteome Network Analysis Identifies Potential Biomarkers for Brain Aging.	J Alzheimers Dis	2023
37905118	Determinants of mosaic chromosomal alteration fitness.	medRxiv	2023
37904051	Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing.	Nat Genet	2023
37802043	Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study.	Am J Hum Genet	2023
37790435	Complexities of cerebral small vessel disease, blood pressure, and dementia relationship: new insights from genetics.	medRxiv	2023
37693453	Key variants via Alzheimer's Disease Sequencing Project whole genome sequence data.	medRxiv	2023
37770635	Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.	Nat Genet	2023
36778386	Structural variation across 138,134 samples in the TOPMed consortium.	Res Sq	2023
37333771	Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations.	HGG Adv	2023
37268629	Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups.	Nat Commun	2023
37015819	Plasma Proteomic Associations With Incident Ischemic Stroke in Older Adults: The Cardiovascular Health Study.	Neurology	2023
36702996	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.	Nat Genet	2023
37392405	Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study.	Alzheimers Dement	2023
37192819	Building a collaborative cloud platform to accelerate heart, lung, blood, and sleep research.	J Am Med Inform Assoc	2023
37126556	Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity.	Sci Adv	2023
37126548	The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.	Sci Adv	2023
36747810	Structural variation across 138,134 samples in the TOPMed consortium.	bioRxiv	2023
37186683	Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease.	Circulation	2023
37046083	Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.	Nature	2023
36927883	Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts.	Neurology	2023
37425772	Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study.	medRxiv	2023
36723951	Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease.	JAMA Cardiol	2023
34700051	Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes.	Biol Psychiatry Cogn Neurosci Neuroimaging	2022
35974141	Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.	Mol Psychiatry	2022
35592775	The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations.	Front Endocrinol (Lausanne)	2022
35527553	Association of Peripheral Lymphocyte Subsets with Cognitive Decline and Dementia: The Cardiovascular Health Study.	J Alzheimers Dis	2022
35396452	Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.	Commun Biol	2022
35511193	Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.	Brain	2022
35385311	Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.	Sci Adv	2022
35504910	DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases.	Nat Commun	2022
36220816	Whole genome sequence analysis of blood lipid levels in >66,000 individuals.	Nat Commun	2022
35379992	New insights into the genetic etiology of Alzheimer's disease and related dementias.	Nat Genet	2022
36213999	Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis.	J Alzheimers Dis	2022
35879306	Polygenic resilience scores capture protective genetic effects for Alzheimer's disease.	Transl Psychiatry	2022
35927319	Rare genetic variants explain missing heritability in smoking.	Nat Hum Behav	2022
35790642	Proteomics and Population Biology in the Cardiovascular Health Study (CHS): design of a study with mentored access and active data sharing.	Eur J Epidemiol	2022
35729114	A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood.	Nat Commun	2022
36056631	A population-based meta-analysis of circulating GFAP for cognition and dementia risk.	Ann Clin Transl Neurol	2022
36411364	Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.	Nat Genet	2022
36050321	Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.	Nat Commun	2022
35915156	Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.	Nat Med	2022
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
34921102	Association of Serum Neurofilament Light Chain Concentration and MRI Findings in Older Adults: The Cardiovascular Health Study.	Neurology	2022
34743536	Clonal Hematopoiesis Is Associated With Higher Risk of Stroke.	Stroke	2022