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Author Details

Roland Riek
ETH Zurich
1986
217
66
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36379877Multi-Dimensional Structure and Dynamics Landscape of Proteins in Mammalian Cells Revealed by In-Cell NMR.Angew Chem Int Ed Engl2023
37614107Nanoscale insights into the local structural rearrangements of amyloid-β induced by bexarotene.Nanoscale2023
37227050Ultrafast Fragment Screening Using Photo-Hyperpolarized (CIDNP) NMR.J Am Chem Soc2023
36723167NMRtist: an online platform for automated biomolecular NMR spectra analysis.Bioinformatics2023
36310195An Efficient Method of Expression and Purification of Amyloid-Beta (Aβ<sub>1-42</sub>) Peptide from E. coli.Methods Mol Biol2023
34812556Prebiotically Plausible Autocatalytic Peptide Amyloids.Chemistry2022
37904864An improved, time-efficient approach to extract accurate distance restraints for <i>N</i>MR<sup>2</sup> structure calculation.Magn Reson (Gott)2022
36460747Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression.Commun Biol2022
35868264The next decade of protein structure.Cell2022
36257955Rapid protein assignments and structures from raw NMR spectra with the deep learning technique ARTINA.Nat Commun2022
36115062Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development.Angew Chem Int Ed Engl2022
35305195Optimization and validation of multi-state NMR protein structures using structural correlations.J Biomol NMR2022
34963060PDBcor: An automated correlation extraction calculator for multi-state protein structures.Structure2022
32964527Nanoscale Hyperspectral Imaging of Amyloid Secondary Structures in Liquid.Angew Chem Int Ed Engl2021
33649211Structural insights into α-synuclein monomer-fibril interactions.Proc Natl Acad Sci U S A2021
33710192Molecular features toward high photo-CIDNP hyperpolariztion explored through the oxidocyclization of tryptophan.Phys Chem Chem Phys2021
34878820Slow-wave sleep affects synucleinopathy and regulates proteostatic processes in mouse models of Parkinson's disease.Sci Transl Med2021
34588645Structural strains of misfolded tau protein define different diseases.Nature2021
34431665Modulating α-Synuclein Liquid-Liquid Phase Separation.Biochemistry2021
34573836Causality in Discrete Time Physics Derived from Maupertuis Reduced Action Principle.Entropy (Basel)2021
34573813On the Entropy of a One-Dimensional Gas with and without Mixing Using Sinai Billiard.Entropy (Basel)2021
34534463The expanding amyloid family: Structure, stability, function, and pathogenesis.Cell2021
34041264Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications.Front Mol Biosci2021
33373227Correction to "Amyloid Fibril Polymorphism: Almost Identical on the Atomic Level, Mesoscopically Very Different".J Phys Chem B2021
33325627Prebiotic Peptide Synthesis and Spontaneous Amyloid Formation Inside a Proto-Cellular Compartment.Angew Chem Int Ed Engl2021
32514159α-Synuclein aggregation nucleates through liquid-liquid phase separation.Nat Chem2020
31802003Regulation of α-synuclein by chaperones in mammalian cells.Nature2020
32042086Neurodegenerative diseases distinguished through protein-structure analysis.Nature2020
33286419Entropy Derived from Causality.Entropy (Basel)2020
33046908The three-dimensional structure of human β-endorphin amyloid fibrils.Nat Struct Mol Biol2020
32632432Half a century of amyloids: past, present and future.Chem Soc Rev2020
32797659Protein Allostery at Atomic Resolution.Angew Chem Int Ed Engl2020
32621003Protein-ligand structure determination with the NMR molecular replacement tool, NMR<sup>2</sup>.J Biomol NMR2020
33014595Detection of cerebral tauopathy in P301L mice using high-resolution large-field multifocal illumination fluorescence microscopy.Biomed Opt Express2020
32696394In-Cell NMR of Intrinsically Disordered Proteins in Mammalian Cells.Methods Mol Biol2020
30548150Rational Structure-Based Design of Fluorescent Probes for Amyloid Folds.Chembiochem2019
31845164Carbonyl Sulfide as a Prebiotic Activation Agent for Stereo- and Sequence-Selective, Amyloid-Templated Peptide Elongation.Orig Life Evol Biosph2019
31815671Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.Elife2019
31864237Atto Thio 12 as a promising dye for photo-CIDNP.J Chem Phys2019
31521608Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity.Cell Syst2019
31365236Nuclear Magnetic Resonance Solution Structure and Functional Behavior of the Human Proton Channel.Biochemistry2019
31167929A cullin-RING ubiquitin ligase targets exogenous α-synuclein and inhibits Lewy body-like pathology.Sci Transl Med2019
31088827Functional Amyloids.Cold Spring Harb Perspect Biol2019
30973010Probing Ion Binding in the Selectivity Filter of the KcsA Potassium Channel.J Am Chem Soc2019
29339755A prebiotic template-directed peptide synthesis based on amyloids.Nat Commun2018
29890117Peptide Amyloids in the Origin of Life.J Mol Biol2018
29969391Cryo-EM structure of alpha-synuclein fibrils.Elife2018
30397651Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins.Sci Adv2018
30289706Lipid- and Cholesterol-Mediated Time-Scale-Specific Modulation of the Outer Membrane Protein X Dynamics in Lipid Bilayers.J Am Chem Soc2018
30306288<sup>15</sup>N transverse relaxation measurements for the characterization of µs-ms dynamics are deteriorated by the deuterium isotope effect on <sup>15</sup>N resulting from solvent exchange.J Biomol NMR2018
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John L Markley
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Collaborators

Kurt W??thrich
iHuman Institute, ShanghaiTech University
Co-authored papers 27
C??dric Eichmann
ETH Zurich
Co-authored papers 16
Witek Kwiatkowski
Swiss Federal Institute of Technology
Co-authored papers 14
Senyon Choe
Joint Center for Biosciences
Co-authored papers 13
Henning Stahlberg
Ecole Polytechnique Federale de Lausanne (EPFL), University of Lausanne
Co-authored papers 11
David Eisenberg
university of california los angeles
Co-authored papers 9
Innokentiy Maslennikov
School of Pharmacy , Chapman University
Co-authored papers 8
Alice Soragni
David Geffen School of Medicine, University of California los angeles
Co-authored papers 7
Paola Picotti
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 4
Monika Bayrhuber
ETH Zurich
Co-authored papers 4
Eliezer Masliah
National Institute On Aging
Co-authored papers 3
Stuart A Lipton
The Scripps Research Institute, University of California
Co-authored papers 2
Duilio Cascio
Co-authored papers 2
Matthias Peter
Institute of Biochemistry, ETH Zurich
Co-authored papers 2
Gerard Manning
Genentech Inc.
Co-authored papers 2
Jeffrey C Hoch
University of Connecticut Health Center
Co-authored papers 2
Markus Britschgi
Roche Pharma Research and Early Development
Co-authored papers 2
Sebastian Hiller
University of Basel
Co-authored papers 2
Tomohiro Nakamura
The Scripps Research Institute
Co-authored papers 2
Paul A Slesinger
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 2
Weston B Struwe
Co-authored papers 1
Julian P Whitelegge
Co-authored papers 1
James M Holton
Lawrence Berkeley National Laboratory
Co-authored papers 1
Sjors H W Scheres
Medical Research Council Laboratory of Molecular Biology
Co-authored papers 1
Feixia Chu
University of New Hampshire
Co-authored papers 1
Bartosz Balana
Janssen Research and Development LLC, Janssen Pharmaceutica N.V.
Co-authored papers 1
Tobias Weiss
Westlake University
Co-authored papers 1
Paula Desplats
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Release 1.2