Skip to Main Content

Author Details

Heather Thorne
Peter MacCallum Cancer Centre
1982
59
29
PMIDPaper TitleJournal TitlePublished Year
36849657Multiomic analysis of homologous recombination-deficient end-stage high-grade serous ovarian cancer.Nat Genet2023
36972661Impact of concurrent tumour events on the prostate cancer outcomes of germline BRCA2 mutation carriers.Eur J Cancer2023
36999648BRCA1 and BRCA2 carriers with breast, ovarian and prostate cancer demonstrate a different pattern of metastatic disease compared with non-carriers: results from a rapid autopsy programme.Histopathology2023
36656928Heritable defects in telomere and mitotic function selectively predispose to sarcomas.Science2023
34965921Weight is More Informative than Body Mass Index for Predicting Postmenopausal Breast Cancer Risk: Prospective Family Study Cohort (ProF-SC).Cancer Prev Res (Phila)2022
35764368Tumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes.J Immunother Cancer2022
35855555Novel germline mutations for active surveillance and imaging strategies in prostate cancer.Curr Opin Urol2022
35892882Novel Germline Mutations in a Cohort of Men with Familial Prostate Cancer.Cancers (Basel)2022
36222710Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes.Clin Cancer Res2022
36010941Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status.Cancers (Basel)2022
35039532Value of the loss of heterozygosity to BRCA1 variant classification.NPJ Breast Cancer2022
34906479Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants.Genet Med2022
35084436Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes.JAMA Oncol2022
34413304The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology.Nat Commun2021
33626496Association between BRCA2 alterations and intraductal and cribriform histologies in prostate cancer.Eur J Cancer2021
33664264Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling.Nat Commun2021
31949161A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.Nat Commun2020
31090900Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers.Ann Oncol2019
31794678A Review of International Biobanks and Networks: Success Factors and Key Benchmarks-A 10-Year Retrospective Review.Biopreserv Biobank2019
30894541Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer.Nat Commun2019
28977728Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate-tolerant cells.BJU Int2018
30049486Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.Eur Urol2018
29429804Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study.Eur Urol2018
27171545Breast cancer risk prediction using a polygenic risk score in the familial setting: a prospective study from the Breast Cancer Family Registry and kConFab.Genet Med2017
35172485Circulating Tumor DNA Analysis and Functional Imaging Provide Complementary Approaches for Comprehensive Disease Monitoring in Metastatic Melanoma.JCO Precis Oncol2017
28430777Correction: The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".PLoS Med2017
28067867Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.Nat Commun2017
28027312The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".PLoS Med2016
26534844Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families.J Med Genet2016
26585945Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer.Urol Oncol2016
27617737A community-based model of rapid autopsy in end-stage cancer patients.Nat Biotechnol2016
24784491Altered significance of D'Amico risk classification in patients with prostate cancer linked to a familial breast cancer (kConFab) cohort.BJU Int2015
26503049Corrigendum: Whole-genome characterization of chemoresistant ovarian cancer.Nature2015
26529019"Cancer 2015": A Prospective, Population-Based Cancer Cohort-Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic.J Pers Med2015
26017449Whole-genome characterization of chemoresistant ovarian cancer.Nature2015
25154392Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis.Eur Urol2015
24489791Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutation.PLoS One2014
22975758Improving mutation notification when new genetic information is identified in research: a trial of two strategies in familial breast cancer.Genet Med2013
23853209Diagnostic chest X-rays and breast cancer risk before age 50 years for BRCA1 and BRCA2 mutation carriers.Cancer Epidemiol Biomarkers Prev2013
22374981Intragenic ATM methylation in peripheral blood DNA as a biomarker of breast cancer risk.Cancer Res2012
23028338Exome sequencing identifies rare deleterious mutations in DNA repair genes FANCC and BLM as potential breast cancer susceptibility alleles.PLoS Genet2012
23035815High grade prostatic intraepithelial neoplasia does not display loss of heterozygosity at the mutation locus in BRCA2 mutation carriers with aggressive prostate cancer.BJU Int2012
21733824Decreased prostate cancer-specific survival of men with BRCA2 mutations from multiple breast cancer families.Cancer Prev Res (Phila)2011
22043063International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).J Natl Cancer Inst Monogr2011
22043047kConFab: a familial breast cancer consortium facilitating research and translational oncology.J Natl Cancer Inst Monogr2011
19724277BRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression.Br J Cancer2009
19648928Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.Nat Med2009
18445692Loss of heterozygosity at the BRCA2 locus detected by multiplex ligation-dependent probe amplification is common in prostate cancers from men with a germline BRCA2 mutation.Clin Cancer Res2008
16507150Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource.Breast Cancer Res2006
17064299Histopathological features of breast cancer in carriers of ATM gene variants.Histopathology2006
  • 1 - 50 of 59

Recommended Authors

Florentine S Hilbers
Netherlands Cancer Institute
Career Start Year 2012
Number of shared co-authors 16
Eric C Polley
Mayo Clinic
Career Start Year 2007
Number of shared co-authors 32
Sarah Thomas
Oncogenetics Team The Institute of Cancer Research London UK.
Career Start Year 2007
Number of shared co-authors 14
Kasmintan A Schrader
University of British Columbia
Career Start Year 2005
Number of shared co-authors 31
Larissa A Korde
Clinical Investigations Branch, National Cancer Institute
Career Start Year 2004
Number of shared co-authors 11
Scott A Tomlins
Rogel Cancer Center, University of Michigan Medical School ann arbor
Career Start Year 2003
Number of shared co-authors 17
Daniel Leongamornlert
Oncogenetics Team The Institute of Cancer Research London UK.
Career Start Year 2003
Number of shared co-authors 22
Siddhartha Deb
Olivia Newton-John Cancer Research Institute
Career Start Year 2002
Number of shared co-authors 12
Andrea Sboner
Institute for Computational Biomedicine
Career Start Year 2000
Number of shared co-authors 16
Louise Izatt
Guy's and St Thomas' NHS Foundation Trust
Career Start Year 1998
Number of shared co-authors 68
Franklin W Huang
Institute for Human Genetics, University of California san francisco
Career Start Year 1998
Number of shared co-authors 10
Rebecca Sutphen
College of Medicine, University of South Florida
Career Start Year 1995
Number of shared co-authors 59
Simon A Gayther
Cedars-Sinai Medical Center
Career Start Year 1993
Number of shared co-authors 95
Arul M Chinnaiyan
University of Michigan Medical School.
Career Start Year 1993
Number of shared co-authors 27
Phillip A Futreal
The University of Texas MD Anderson Cancer Center
Career Start Year 1991
Number of shared co-authors 42
Timothy R Rebbeck
Center for Cancer Equity and Engagement, Dana-Farber/Harvard Cancer Center
Career Start Year 1991
Number of shared co-authors 62
Ben Ho Park
Vanderbilt University Medical Center
Career Start Year 1990
Number of shared co-authors 4
James M Ford
Stanford University
Career Start Year 1989
Number of shared co-authors 10
John W M Martens
Erasmus Medical Center (MC) Cancer Institute
Career Start Year 1989
Number of shared co-authors 74
Zsofia Kote-Jarai
The Institute of Cancer Research
Career Start Year 1988
Number of shared co-authors 61
Barbara L Weber
Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania
Career Start Year 1988
Number of shared co-authors 49
Wendy S Rubinstein
CancerLinQ LLC, American Society of Clinical Oncology
Career Start Year 1987
Number of shared co-authors 42
Katherine L Nathanson
Perelman School of Medicine, University of Pennsylvania, USA Abramson Cancer Center
Career Start Year 1986
Number of shared co-authors 79
Alvaro N A Monteiro
H. Lee Moffitt Cancer Center & Research Institute
Career Start Year 1985
Number of shared co-authors 64
Kathleen A Cooney
Duke University School of Medicine, and the Duke Cancer Institute
Career Start Year 1982
Number of shared co-authors 26
Rosalind A Eeles
The Institute of Cancer Research
Career Start Year 1982
Number of shared co-authors 98
William B Isaacs
The Brady Urological Institute, The Johns Hopkins School of Medicine
Career Start Year 1979
Number of shared co-authors 36
Jeffrey S Ross
Foundation Medicine
Career Start Year 1974
Number of shared co-authors 10
Francesca Demichelis
University of Trento
Career Start Year 1969
Number of shared co-authors 16
William D Foulkes
Segal Cancer Centre, Jewish General Hospital
Career Start Year 1962
Number of shared co-authors 85

Collaborators

David Clouston
Co-authored papers 12
Damien Bolton
University of Melbourne
Co-authored papers 11
David D L Bowtell
Peter MacCallum Cancer Centre
Co-authored papers 11
Kathryn Alsop
Peter MacCallum Cancer Centre
Co-authored papers 10
Georgia Chenevix-Trench
QIMR Berghofer Medical Research Institute
Co-authored papers 9
Renea A Taylor
Peter MacCallum Cancer Centre
Co-authored papers 9
Gillian Mitchell
Familial Cancer Centre Peter MacCallum Cancer Centre Parkville Victoria 0 Australia.
Co-authored papers 8
Amanda B Spurdle
QIMR Berghofer Medical Research Institute
Co-authored papers 7
Gail P Risbridger
Biomedicine Discovery Institute, Monash University
Co-authored papers 7
Declan G Murphy
Peter MacCallum Cancer Centre, University of Melbourne
Co-authored papers 7
Mitchell G Lawrence
Biomedicine Discovery Institute, Monash University
Co-authored papers 6
Judy Kirk
Co-authored papers 6
Melissa Papargiris
Biomedicine Discovery Institute, Monash University
Co-authored papers 6
Irene L Andrulis
University of Toronto
Co-authored papers 6
Sian Fereday
Peter MacCallum Cancer Centre
Co-authored papers 6
Mark Frydenberg
Monash University
Co-authored papers 5
Mary Beth Terry
Co-authored papers 5
Graham G Giles
Co-authored papers 5
Esther M John
Co-authored papers 5
George Au-Yeung
The University of Melbourne
Co-authored papers 4
Roger L Milne
Co-authored papers 4
John V Pearson
QIMR Berghofer Medical Research Institute
Co-authored papers 4
Ian G Campbell
Co-authored papers 4
Anna DeFazio
Westmead Hospital
Co-authored papers 4
Nicola Waddell
QIMR Berghofer Medical Research Institute
Co-authored papers 4
David E Goldgar
University of Utah
Co-authored papers 4
Joy Hendley
Peter MacCallum Cancer Centre
Co-authored papers 4
Robert Brown
Ovarian Cancer Action Research Centre, Imperial College London
Co-authored papers 3
Jonathan Beesley
QIMR Berghofer Medical Research Institute
Co-authored papers 3
Maria A Doyle
Peter MacCallum Cancer Centre
Co-authored papers 3
Release 1.2