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Author Details

David A Wagner
Metabolic Solutions Inc.
1981
50
28
PMIDPaper TitleJournal TitlePublished Year
35974248Publisher Correction: Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study.Nat Metab2022
34294923Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study.Nat Metab2021
34494088Colonic Fermentation and Acetate Production in Youth with and without Obesity.J Nutr2021
30651324An engineered <i>E. coli</i> Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans.Sci Transl Med2019
29443397Whole Body Protein Turnover and Net Protein Balance After Pediatric Thoracic Surgery: A Noninvasive Single-Dose [15] N Glycine Stable Isotope Protocol With End-Product Enrichment.JPEN J Parenter Enteral Nutr2018
27648960Role of Gut Microbiota and Short Chain Fatty Acids in Modulating Energy Harvest and Fat Partitioning in Youth.J Clin Endocrinol Metab2016
25293624Use of an oral stable isotope label to confirm variation in red blood cell mean age that influences HbA1c interpretation.Am J Hematol2015
25527748Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis.Am J Clin Nutr2015
24297161Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.Invest New Drugs2014
21642471Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate.J Clin Pharmacol2012
22030902Quantitative liver function tests improve the prediction of clinical outcomes in chronic hepatitis C: results from the Hepatitis C Antiviral Long-term Treatment Against Cirrhosis Trial.Hepatology2012
21697586A new 13C breath test to detect vitamin B12 deficiency: a prevalent and poorly diagnosed health problem.J Breath Res2011
20016461A super-agonist of growth hormone-releasing hormone causes rapid improvement of nutritional status in patients with chronic kidney disease.Kidney Int2010
19053983Quantitative tests of liver function measure hepatic improvement after sustained virological response: results from the HALT-C trial.Aliment Pharmacol Ther2009
18266997The spectrum of hepatic functional impairment in compensated chronic hepatitis C: results from the Hepatitis C Anti-viral Long-term Treatment against Cirrhosis Trial.Aliment Pharmacol Ther2008
17219071Quantifying gastric Helicobacter pylori infection: a comparison of quantitative culture, urease breath testing, and histology.Dig Dis Sci2007
17204956Comparison of the 13C-urea blood test to histology and rapid urease testing in the diagnosis of Helicobacter pylori infection in children.J Pediatr Gastroenterol Nutr2007
16225498Evaluation of the Ez-HBT Helicobacter blood test to establish Helicobacter pylori eradication.Aliment Pharmacol Ther2005
14684756Effect of triglyceride structure on fecal excretion of 13C-labeled triglycerides.J Am Coll Nutr2003
14559930Dysprosium chloride as a nonabsorbable gastrointestinal marker for studies of stable isotope-labeled triglyceride excretion in man.J Am Coll Nutr2003
12426516Cytochrome P450 3A4 and P-glycoprotein mediate the interaction between an oral erythromycin breath test and rifampin.Clin Pharmacol Ther2002
12141833Simultaneous measurement of gastric emptying with a simple muffin meal using [13C]octanoate breath test and scintigraphy in normal subjects and patients with dyspeptic symptoms.Dig Dis Sci2002
8218425Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies.Biol Mass Spectrom1993
8463438Performance of human mass balance/metabolite identification studies using stable isotope (13C, 15N) labeling and continuous-flow isotope-ratio mass spectrometry as an alternative to radioactive labeling methods.J Clin Pharmacol1993
1858701Methionine kinetics and balance at the 1985 FAO/WHO/UNU intake requirement in adult men studied with L-[2H3-methyl-1-13C]methionine as a tracer.Am J Clin Nutr1991
1858702Methionine kinetics in adult men: effects of dietary betaine on L-[2H3-methyl-1-13C]methionine.Am J Clin Nutr1991
1858703Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes.Am J Clin Nutr1991
1858704Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes.Am J Clin Nutr1991
1858705Proline metabolism in adult male burned patients and healthy control subjects.Am J Clin Nutr1991
2104252Adaptation to low-protein diets in renal failure: leucine turnover and nitrogen balance.J Am Soc Nephrol1990
2107210Measurement of very low density and low density lipoprotein apolipoprotein (Apo) B-100 and high density lipoprotein Apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding.J Clin Invest1990
2185662[1-13C; methyl-2H3]methionine kinetics in humans: methionine conservation and cystine sparing.Am J Physiol1990
2372053Quantitative role of splanchnic region in leucine metabolism: L-[1-13C,15N]leucine and substrate balance studies.Am J Physiol1990
2375297Plasma proline kinetics and concentrations in young men in response to dietary proline deprivation.Am J Clin Nutr1990
2246967Prolonged fasting as conditioned by prior protein depletion: effect on urinary nitrogen excretion and whole-body protein turnover.Metabolism1990
2551178Recovery of 13C in breath from NaH13CO3 infused by gut and vein: effect of feeding.Am J Physiol1989
3128190A kinetic study of leucine metabolism in severely burned patients. Comparison between a conventional and branched-chain amino acid-enriched nutritional therapy.Ann Surg1988
3355525Synthesis and degradation of collagens in skin of healthy and protein-malnourished rats in vivo, studied by 18O2 labelling.Biochem J1988
3421329Quantitative study in vivo of methionine cycle in humans using [methyl-2H3]- and [1-13C]methionine.Am J Physiol1988
3670073Plasma proline kinetics and the regulation of proline synthesis in man.Metabolism1987
3159503Pharmacokinetics of nitrate in humans: role of gastrointestinal absorption and metabolism.Carcinogenesis1985
4063996Effect of vitamins C and E on endogenous synthesis of N-nitrosamino acids in humans: precursor-product studies with [15N]nitrate.Cancer Res1985
4091806Nitrate biosynthesis in the rat. Precursor-product relationships with respect to ammonia.Biochem J1985
6533011Modulation of endogenous synthesis of N-nitrosamino acids in humans.IARC Sci Publ1984
6533015Mammalian nitrate biochemistry: metabolism and endogenous synthesis.IARC Sci Publ1984
6831427Metabolic fate of an oral dose of 15N-labeled nitrate in humans: effect of diet supplementation with ascorbic acid.Cancer Res1983
6348771Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment.Proc Natl Acad Sci U S A1983
6800650Interaction of dietary fat and the thymus in the induction of mammary tumors by 7,12-dimethylbenz(a)anthracene.Cancer Res1982
7181105Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids.Anal Biochem1982
6950416Nitrate biosynthesis in man.Proc Natl Acad Sci U S A1981
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Collaborators

Nicola Santoro
Co-authored papers 2
Elizabeth J Parks
University of Missouri
Co-authored papers 2
Jerry Vockley
Co-authored papers 2
Taimour Y Langaee
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Co-authored papers 2
John A Phillips
Vanderbilt University Medical Center
Co-authored papers 2
Mitchell B Cohen
University of Alabama at Birmingham
Co-authored papers 2
Jacqueline M Hibbert
Morehouse School of Medicine
Co-authored papers 1
Eric P Smith
University of Cincinnati College of Medicine
Co-authored papers 1
Christopher J Lindsell
Duke University
Co-authored papers 1
Mary Colleen Rogge
Cincinnati VA Medical Center
Co-authored papers 1
Paramjit K Khera
University of Cincinnati College of Medicine
Co-authored papers 1
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Co-authored papers 1
Shilpa Mehta
New York Medical College
Co-authored papers 1
Franz Schaefer
University Children's Hospital Heidelberg
Co-authored papers 1
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University of Cincinnati College of Medicine
Co-authored papers 1
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Mary F Paine
Washington State University
Co-authored papers 1
Clinton H Joiner
Emory University School of Medicine
Co-authored papers 1
Shannon Haggerty
University of Cincinnati College of Medicine
Co-authored papers 1
Mary B Palascak
University of Cincinnati College of Medicine.
Co-authored papers 1
Robert M Cohen
University of Cincinnati and Cincinnati VA Medical Center
Co-authored papers 1
Paul B Watkins
UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill
Co-authored papers 1
Release 1.2