Skip to Main Content

Author Details

Helena Safavi-Hemami
2010
49
21
PMIDPaper TitleJournal TitlePublished Year
37535677A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3.2023
37720554A toxin-based approach to neuropeptide and peptide hormone discovery.2023
37689602Identification of sodium channel toxins from marine cone snails of the subgenera Textilia and Afonsoconus.Cell Mol Life Sci2023
36827123Characterisation of Elevenin-Vc1 from the Venom of : A Structural Analogue of α-Conotoxins.2023
35265668Integrating Venom Peptide Libraries Into a Phylogenetic and Broader Biological Framework.Frontiers in Molecular Biosciences2022
35893752A Novel Dimeric Conotoxin, FrXXA, from the Vermivorous Cone Snail , of the Eastern Pacific, Inhibits Nicotinic Acetylcholine Receptors.Toxins2022
35761080Unconventional insulins from predators and pathogens.Nature Chemical Biology2022
35383850Reconstructing the Origins of the Somatostatin and Allatostatin-C Signaling Systems Using the Accelerated Evolution of Biodiverse Cone Snail Toxins.Molecular Biology and Evolution2022
35289328Symmetric and asymmetric receptor conformation continuum induced by a new insulin.Nature Chemical Biology2022
34405535DisCoTune: versatile auxiliary plasmids for the production of disulphide-containing proteins and peptides in the E. coli T7 system.Microbial Biotechnology2021
34054536Non-Peptidic Small Molecule Components from Cone Snail Venoms.Frontiers in Pharmacology2021
33764053Discovery of a Potent Conorfamide from Using a Novel Zebrafish Larvae Assay.Journal of Natural Products2021
33712468Small-molecule mimicry hunting strategy in the imperial cone snail, .Science advances2021
32784699Purification and Characterization of the Pink-Floyd Drillipeptide, a Bioactive Venom Peptide from (Gastropoda: Conoidea: Drilliidae).Toxins2020
32333764Transcriptomic Profiling Reveals Extraordinary Diversity of Venom Peptides in Unexplored Predatory Gastropods of the Genus Clavus.Genome Biol Evol2020
32483339A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.Nature Structural and Molecular Biology2020
32533129Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.Nature Structural and Molecular Biology2020
30747102Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor.eLife2019
29777871Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways.Journal of Proteomics2019
30975904The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework.J Biol Chem2019
30243794Conopeptides promote itch through human itch receptor hMgprX1.Toxicon2018
30513724Discovery of Novel Conotoxin Candidates Using Machine Learning.Toxins (Basel)2018
30384459Ero1-Mediated Reoxidation of Protein Disulfide Isomerase Accelerates the Folding of Cone Snail Toxins.International Journal of Molecular Sciences2018
26301480Hormone-like peptides in the venoms of marine cone snails.Gen Comp Endocrinol2017
28689026Venom peptides as pharmacological tools and therapeutics for diabetes.Neuropharmacology2017
28551870Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study.Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology2017
28531118The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea.Mar Drugs2017
28479398Isolation and characterization of Conohyal-P1, a hyaluronidase from the injected venom of Conus purpurascens.Journal of Proteomics2017
28922871Divergence of the Venom Exogene Repertoire in Two Sister Species of Turriconus.Genome Biol Evol2017
27777069Insulin as a weapon.Toxicon2016
26957604Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides.Proc Natl Acad Sci U S A2016
26947243A prominent role of PDIA6 in processing of misfolded proinsulin.Biochim Biophys Acta2016
26774129A Naturally Occurring Peptide with an Elementary Single Disulfide-Directed β-Hairpin Fold.Structure2016
27617429A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.Nature Structural and Molecular Biology2016
27524826Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa.Mol Biol Evol2016
25605914Specialized insulin is used for chemical warfare by fish-hunting cone snails.Proc Natl Acad Sci U S A2015
25848010Insights into the origins of fish hunting in venomous cone snails from studies of Conus tessulatus.Proceedings of the National Academy of Sciences of the United States of America2015
25464369Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom.J Proteomics2015
25412008Pancreatic beta cells are highly susceptible to oxidative and ER stresses during the development of diabetes.J Proteome Res2015
25007141The Opisthorchis viverrini genome provides insights into life in the bile duct.Nat Commun2014
24478445Combined proteomic and transcriptomic interrogation of the venom gland of Conus geographus uncovers novel components and functional compartmentalization.Mol Cell Proteomics2014
24505301Diversity of conotoxin gene superfamilies in the venomous snail, Conus victoriae.PLoS One2014
23872086High molecular weight components of the injected venom of fish-hunting cone snails target the vascular system.J Proteomics2013
22891240Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails.J Biol Chem2012
21707029Specialisation of the venom gland proteome in predatory cone snails reveals functional diversification of the conotoxin biosynthetic pathway.J Proteome Res2011
21504902Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?J Biol Chem2011
20147296Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins.J Biol Chem2010
20442851Characterisation of nitric oxide synthase in three cnidarian-dinoflagellate symbioses.PLoS ONE2010
20818826Proteomic interrogation of venom delivery in marine cone snails: novel insights into the role of the venom bulb.J Proteome Res2010
  • 1 - 49 of 49

Recommended Authors

Collaborators

Co-authored papers 29
Monash Biomedicine Discovery Institute, Monash University
Co-authored papers 16
Co-authored papers 15
Co-authored papers 11
University of Utah
Co-authored papers 10
Co-authored papers 9
Co-authored papers 4
Co-authored papers 4
Co-authored papers 4
Co-authored papers 4
Co-authored papers 3
University of Massachusetts Medical School
Co-authored papers 1
Heidelberg University
Co-authored papers 1
Co-authored papers 1
Aerospace Center Hospital
Co-authored papers 1
Co-authored papers 1
California Institute of Technology
Co-authored papers 1
Co-authored papers 1