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Full Name
Sebastian D Fugmann
Affiliation
Institute of Biomedical Sciences, College of Medicine, Chang Gung University
ORCID
Career Start Year
1998
Papers
46
H Index
21
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36306972
Functional characterization of the MyD88 homologs in Strongylocentrotus purpuratus.
Dev Comp Immunol
2023
37788234
Polystyrene-colonizing bacteria are enriched for long-chain alkane degradation pathways.
PLoS One
2023
34870814
Measuring Mutator Enzyme Activity Using an E. coli-Based Colony Formation Assay.
Methods Mol Biol
2022
33858841
Trajectory mapping of the early <i>Drosophila</i> germline reveals controls of zygotic activation and sex differentiation.
Genome Res
2021
29769532
AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates.
Nat Commun
2018
28539513
Evidence for parallel evolution of a gene involved in the regulation of spermatogenesis.
Proc Biol Sci
2017
29125863
Lectins identify distinct populations of coelomocytes in Strongylocentrotus purpuratus.
PLoS One
2017
27056670
Collaboration of RAG2 with RAG1-like proteins during the evolution of V(D)J recombination.
Genes Dev
2016
24491483
Pharmacophore model of the quercetin binding site of the SIRT6 protein.
J Mol Graph Model
2014
24549092
Form follows function - the three-dimensional structure of antigen receptor gene loci.
Curr Opin Immunol
2014
24704183
The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads.
J Chromatogr B Analyt Technol Biomed Life Sci
2014
23376017
Synthesis and characterization of a SIRT6 open tubular column: predicting deacetylation activity using frontal chromatography.
Anal Biochem
2013
22817885
Transcription, splicing, and release: are we there yet?
Cell
2012
21295456
Targeting of AID-mediated sequence diversification to immunoglobulin genes.
Curr Opin Immunol
2011
21854049
Synthesis and characterization of SIRT6 protein coated magnetic beads: identification of a novel inhibitor of SIRT6 deacetylase from medicinal plant extracts.
Anal Chem
2011
21844395
Separation of mutational and transcriptional enhancers in Ig genes.
J Immunol
2011
21533098
Classical Mus musculus Igκ enhancers support transcription but not high level somatic hypermutation from a V-lambda promoter in chicken DT40 cells.
PLoS One
2011
21701980
Characterizing somatic hypermutation and gene conversion in the chicken DT40 cell system.
Methods Mol Biol
2011
21349423
RAG-2 unleashed: lymphocytes beware.
Immunity
2011
20004590
The origins of the Rag genes--from transposition to V(D)J recombination.
Semin Immunol
2010
20651744
The origins of vertebrate adaptive immunity.
Nat Rev Immunol
2010
19841648
A coming-of-age story: activation-induced cytidine deaminase turns 10.
Nat Immunol
2009
18023479
AID-mediated diversification within the IgL locus of chicken DT40 cells is restricted to the transcribed IgL gene.
Mol Immunol
2008
18499250
The PHD domain of the sea urchin RAG2 homolog, SpRAG2L, recognizes dimethylated lysine 4 in histone H3 tails.
Dev Comp Immunol
2008
18250404
Cutting edge: a cis-acting DNA element targets AID-mediated sequence diversification to the chicken Ig light chain gene locus.
J Immunol
2008
17613522
Activation-induced cytidine deaminase-mediated sequence diversification is transiently targeted to newly integrated DNA substrates.
J Biol Chem
2007
17636023
The beyond 12/23 restriction is imposed at the nicking and pairing steps of DNA cleavage during V(D)J recombination.
Mol Cell Biol
2007
16505374
An ancient evolutionary origin of the Rag1/2 gene locus.
Proc Natl Acad Sci U S A
2006
17095691
The genome of the sea urchin Strongylocentrotus purpuratus.
Science
2006
17027739
The immune gene repertoire encoded in the purple sea urchin genome.
Dev Biol
2006
17178919
Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences.
J Exp Med
2006
15039385
Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination.
Int Immunol
2004
15326342
Immunology. UNGstoppable switching.
Science
2004
14991614
Non-redundancy of cytidine deaminases in class switch recombination.
Eur J Immunol
2004
12530976
Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells.
Immunity
2003
14551903
A functional analysis of the spacer of V(D)J recombination signal sequences.
PLoS Biol
2003
12615897
Defective DNA repair and increased genomic instability in Artemis-deficient murine cells.
J Exp Med
2003
12719733
RNA AIDS DNA.
Nat Immunol
2003
11847327
Immunology. One AID to unite them all.
Science
2002
11961538
DNA repair: breaking the seal.
Nature
2002
11417858
RAG1 and RAG2 in V(D)J recombination and transposition.
Immunol Res
2001
11684024
Identification of basic residues in RAG2 critical for DNA binding by the RAG1-RAG2 complex.
Mol Cell
2001
10678172
Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.
Mol Cell
2000
10837067
The RAG proteins and V(D)J recombination: complexes, ends, and transposition.
Annu Rev Immunol
2000
9809069
DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes.
Mol Cell
1998
9921912
Mutations in the gene for the common gamma chain (gammac) in X-linked severe combined immunodeficiency.
Hum Genet
1998
1 - 46 of 46
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