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Author Details

Roman Jerala
National Institute of Chemistry
1988
221
48
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36163385Chemically inducible split protein regulators for mammalian cells.Nat Chem Biol2023
37486611Crystal Structure of <i>de Novo</i> Designed Coiled-Coil Protein Origami Triangle.J Am Chem Soc2023
37586657Lipid droplets control mitogenic lipid mediator production in human cancer cells.Mol Metab2023
38042897Programmable de novo designed coiled coil-mediated phase separation in mammalian cells.Nat Commun2023
37532706A multiplexed bacterial two-hybrid for rapid characterization of protein-protein interactions and iterative protein design.Nat Commun2023
37223115Regulation of CD19 CAR-T cell activation based on an engineered downstream transcription factor.Mol Ther Oncolytics2023
37308636Coiled-Coil Protein Origami: Design, Isolation, and Characterization.Methods Mol Biol2023
37234478Engineered combinatorial cell device for wound healing and bone regeneration.Front Bioeng Biotechnol2023
37031229Segmentation strategy of de novo designed four-helical bundles expands protein oligomerization modalities for cell regulation.Nat Commun2023
36173575Concatenated Coiled-Coil Tag for Highly Efficient, Small Molecule-Inducible Upregulation of Endogenous Mammalian Genes.Methods Mol Biol2023
35260576Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage.Nat Commun2022
35739111Coiled-coil heterodimer-based recruitment of an exonuclease to CRISPR/Cas for enhanced gene editing.Nat Commun2022
35802180Proteolytically Activated CRAC Effectors through Designed Intramolecular Inhibition.ACS Synth Biol2022
35670660Binding of the transcription activator-like effector augments transcriptional regulation by another transcription factor.Nucleic Acids Res2022
35430555Designed protease-based signaling networks.Curr Opin Chem Biol2022
35714197Metal ion-regulated assembly of designed modular protein cages.Sci Adv2022
35682872The Relevance of Physico-Chemical Properties and Protein Corona for Evaluation of Nanoparticles Immunotoxicity-In Vitro Correlation Analysis on THP-1 Macrophages.Int J Mol Sci2022
36293418Correlation between Phenotype and Genotype in CTNNB1 Syndrome: A Systematic Review of the Literature.Int J Mol Sci2022
35069570Cleavage-Mediated Regulation of Myd88 Signaling by Inflammasome-Activated Caspase-1.Front Immunol2022
32945079Distinctive probiotic features share common TLR2-dependent signalling in intestinal epithelial cells.Cell Microbiol2021
33911109Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion.Sci Rep2021
33574262Designed folding pathway of modular coiled-coil-based proteins.Nat Commun2021
33574245Self-assembly and regulation of protein cages from pre-organised coiled-coil modules.Nat Commun2021
33815382Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics.Front Immunol2021
33925446A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response.Vaccines (Basel)2021
33893235A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.Proc Natl Acad Sci U S A2021
33727540Author Correction: Self-assembly and regulation of protein cages from pre-organised coiled-coil modules.Nat Commun2021
34771026Robust Saliva-Based RNA Extraction-Free One-Step Nucleic Acid Amplification Test for Mass SARS-CoV-2 Monitoring.Molecules2021
34004056Disruption of disulfides within RBD of SARS-CoV-2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs.FASEB J2021
33451032Novel Regeneration Approach for Creating Reusable FO-SPR Probes with NTA Surface Chemistry.Nanomaterials (Basel)2021
33476117Triangular <i>in Vivo</i> Self-Assembling Coiled-Coil Protein Origami.ACS Chem Biol2021
33289352A guide to the design of synthetic gene networks in mammalian cells.FEBS J2021
32401336Increased gene translation stringency in mammalian cells by nonsense suppression at multiple permissive sites with a single noncanonical amino acid.FEBS Lett2020
31907374A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells.Nat Chem Biol2020
32973091Synergy between 15-lipoxygenase and secreted PLA<sub>2</sub> promotes inflammation by formation of TLR4 agonists from extracellular vesicles.Proc Natl Acad Sci U S A2020
32823878Adamantane Containing Peptidoglycan Fragments Enhance RANTES and IL-6 Production in Lipopolysaccharide-Induced Macrophages.Molecules2020
32591764Publisher Correction: Building an international consortium for tracking coronavirus health status.Nat Med2020
32647829Molecular assemblies built with the artificial protein Pizza.J Struct Biol X2020
32643923Engineering and Rewiring of a Calcium-Dependent Signaling Pathway.ACS Synth Biol2020
32448937Metabolic enzyme clustering by coiled coils improves the biosynthesis of resveratrol and mevalonate.AMB Express2020
32283934Targeted Delivery of Adamantylated Peptidoglycan Immunomodulators in Lipid Nanocarriers: NMR Shows That Cargo Fragments Are Available on the Surface.J Phys Chem B2020
32505942Design of novel protein building modules and modular architectures.Curr Opin Struct Biol2020
32324903Synthetic biology principles for the design of protein with novel structures and functions.FEBS Lett2020
30583910Recombinant flagellins with deletions in domains D1, D2, and D3: Characterization as novel immunoadjuvants.Vaccine2019
31832140CRISPRa-mediated <i>FOXP3</i> gene upregulation in mammalian cells.Cell Biosci2019
30957491Synthetic Biology for Multiscale Designed Biomimetic Assemblies: From Designed Self-Assembling Biopolymers to Bacterial Bioprinting.Biochemistry2019
30782846Design of split superantigen fusion proteins for cancer immunotherapy.J Biol Chem2019
30455466Polarized displacement by transcription activator-like effectors for regulatory circuits.Nat Chem Biol2019
30531965Design of fast proteolysis-based signaling and logic circuits in mammalian cells.Nat Chem Biol2019
30696900Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties.Sci Rep2019
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Collaborators

National Institute of Chemistry
Co-authored papers 43
Jozef Stefan Institute
Co-authored papers 27
National Institute of Chemistry
Co-authored papers 24
National Institute of Chemistry
Co-authored papers 21
Jozef Stefan Institute
Co-authored papers 15
National Institute of Chemistry
Co-authored papers 6
University of Ljubljana
Co-authored papers 4
Lek Pharmaceuticals, Technical Research & Development Novartis
Co-authored papers 4
National Centre for Biotechnology (CNB CSIC), Campus Universidad Autonoma de Madrid
Co-authored papers 3
University of Sheffield
Co-authored papers 2
King's College London BHF Centre for Research Excellence
Co-authored papers 2
Harvard T.H. Chan School of Public Health
Co-authored papers 1
Clalit Health Services, Ben Gurion University
Co-authored papers 1
ETH Zurich, University Hospital Zurich
Co-authored papers 1
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 1
Jozef Stefan Institute
Co-authored papers 1
King's College London
Co-authored papers 1
ETH Zurich
Co-authored papers 1
University of Colorado Anschutz School of Medicine
Co-authored papers 1
Weizmann Institute of Science
Co-authored papers 1
University of Luxembourg
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Max Planck Institute for Developmental Biology
Co-authored papers 1
Institute for Computational Biomedicine
Co-authored papers 1
Karolinska Institutet
Co-authored papers 1
Jozef Stefan Institute
Co-authored papers 1
Center for Molecular Biology (ZMBH), University of Heidelberg
Co-authored papers 1
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 1