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Author Details

Adam V Wisnewski
Yale University School of Medicine
1991
80
24
Wade Schulz (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36222594MIF is a common genetic determinant of COVID-19 symptomatic infection and severity.QJM2023
36893070Occupational Risk Factors for SARS-CoV-2 Seropositivity in Healthcare Workers: Results of a Longitudinal Cohort.J Occup Environ Med2023
35028957Severe asthma and death in a worker using methylene diphenyl diisocyanate MDI asthma death.Am J Ind Med2022
35839242Glutathione reactivity with aliphatic polyisocyanates.PLoS One2022
36550362Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein.Sci Rep2022
36054278Changes Over Time in COVID-19 Incidence, Vaccinations, Serum Spike IgG, and Viral Neutralizing Potential Among Individuals From a North American Gaming Venue: December 2020-August 2021.J Occup Environ Med2022
35041700Development and utilization of a surrogate SARS-CoV-2 viral neutralization assay to assess mRNA vaccine responses.PLoS One2022
34145437Author Correction: Delayed production of neutralizing antibodies correlates with fatal COVID-19.Nat Med2021
34647343Reply to letter to the editor concerning Gui et al. Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory.Am J Ind Med2021
34499652Immunogenic amino acid motifs and linear epitopes of COVID-19 mRNA vaccines.PLoS One2021
34460832Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel.PLoS One2021
34133415Human IgG and IgA responses to COVID-19 mRNA vaccines.PLoS One2021
32302507Molecular Characterization and Experimental Utility of Monoclonal Antibodies with Specificity for Aliphatic Di- and Polyisocyanates.Monoclon Antib Immunodiagn Immunother2020
32101465Analysis of Lung Gene Expression Reveals a Role for Cl<sup>-</sup> Channels in Diisocyanate-induced Airway Eosinophilia in a Mouse Model of Asthma Pathology.Am J Respir Cell Mol Biol2020
33398304Kinetics of antibody responses dictate COVID-19 outcome.medRxiv2020
30395213Development and Validation of LC-MS-MS Assay for the Determination of the Emerging Alkylating Agent Laromustine and Its Active Metabolite in Human Plasma.J Chromatogr Sci2019
31143884LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.EC Pharmacol Toxicol2019
30724074Dilysine-Methylene Diphenyl Diisocyanate (MDI), a Urine Biomarker of MDI Exposure?Chem Res Toxicol2019
28629263Mass spectrometry-based analysis of murine bronchoalveolar lavage fluid following respiratory exposure to 4,4'-methylene diphenyl diisocyanate aerosol.Xenobiotica2018
28489470Reaction products of hexamethylene diisocyanate vapors with "self" molecules in the airways of rabbits exposed via tracheostomy.Xenobiotica2018
29175138Polymerization of hexamethylene diisocyanate in solution and a 260.23 m/z [M+H]<sup>+</sup> ion in exposed human cells.Anal Biochem2018
27440490Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients.Xenobiotica2017
28124752Automation of sample preparation for mass cytometry barcoding in support of clinical research: protocol optimization.Anal Bioanal Chem2017
27784537Corrigendum to "Identification of novel reaction products of methylene-biS-phenylisocyanate ("MDI") with oxidized glutathione in aqueous solution and also during incubation of MDI with a murine hepatic S9 fraction" [Toxicol. In vitro (2016) 97-104].Toxicol In Vitro2017
27919805UPLC-MS for metabolomics: a giant step forward in support of pharmaceutical research.Drug Discov Today2017
26847541Mass cytometry moving forward in support of clinical research: advantages and considerations.Bioanalysis2016
26678254In vitro cleavage of diisocyanate-glutathione conjugates by human gamma-glutamyl transpeptidase-1.Xenobiotica2016
27124286The influence of diisocyanate antigen preparation methodology on monoclonal and serum antibody recognition.J Occup Environ Hyg2016
27453132Identification of novel reaction products of methylene-bis-phenylisocyanate ("MDI") with oxidized glutathione in aqueous solution and also during incubation of MDI with a murine hepatic S9 fraction.Toxicol In Vitro2016
27323800Progress in automation of mass cytometry barcoding for drug development.Bioanalysis2016
27278961Biotransformation and Rearrangement of Laromustine.Drug Metab Dispos2016
26690039Immunochemical detection of the occupational allergen, methylene diphenyl diisocyanate (MDI), in situ.J Immunol Methods2016
25798740Metabolic disposition of the anti-cancer agent [(14)C]laromustine in male rats.Xenobiotica2015
26092491Impact of recent innovations in the use of mass cytometry in support of drug development.Drug Discov Today2015
25635619Glutathione reaction products with a chemical allergen, methylene-diphenyl diisocyanate, stimulate alternative macrophage activation and eosinophilic airway inflammation.Chem Res Toxicol2015
25266741Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: initial one-year follow-up.Am J Ind Med2014
23295252Molecular determinants of humoral immune specificity for the occupational allergen, methylene diphenyl diisocyanate.Mol Immunol2013
23791970Connecting glutathione with immune responses to occupational methylene diphenyl diisocyanate exposure.Chem Biol Interact2013
23178851Hexamethylene diisocyanate (HDI) vapor reactivity with glutathione and subsequent transfer to human albumin.Toxicol In Vitro2013
22206939Vapor conjugation of toluene diisocyanate to specific lysines of human albumin.Anal Biochem2012
22449630Biomonitoring Hexamethylene diisocyanate (HDI) exposure based on serum levels of HDI-specific IgG.Ann Occup Hyg2012
21414210Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses.J Occup Med Toxicol2011
21806041Toluene diisocyanate reactivity with glutathione across a vapor/liquid interface and subsequent transcarbamoylation of human albumin.Chem Res Toxicol2011
21978852Pathogenesis and disease mechanisms of occupational asthma.Immunol Allergy Clin North Am2011
20123080Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate.Anal Biochem2010
20545707Pro/Con debate: Is occupational asthma induced by isocyanates an immunoglobulin E-mediated disease?Clin Exp Allergy2010
18498542Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI-albumin conjugates.Clin Exp Allergy2008
17351466Developments in laboratory diagnostics for isocyanate asthma.Curr Opin Allergy Clin Immunol2007
17581205Diisocyanate conjugate and immunoassay characteristics influence detection of specific antibodies in HDI-exposed workers.Clin Exp Allergy2007
17656675Respiratory symptoms, sensitization, and exposure response relationships in spray painters exposed to isocyanates.Am J Respir Crit Care Med2007
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Collaborators

Yale University School of Medicine
Co-authored papers 29
Yale University
Co-authored papers 5
Instituto Goncalo Moniz, Yale School of Public Health
Co-authored papers 4
Yale School of Medicine
Co-authored papers 3
Yale School of Public Health
Co-authored papers 3
Yale University School of Medicine
Co-authored papers 3
Yale University
Co-authored papers 3
School of Public Health, Yale University
Co-authored papers 3
Dalla Lana School of Public Health, University of Toronto
Co-authored papers 2
Yale University School of Medicine
Co-authored papers 2
Yale University School of Medicine
Co-authored papers 2
Yale School of Medicine
Co-authored papers 2
Yale University School of Medicine
Co-authored papers 2
Co-authored papers 2
Yale University School of Medicine
Co-authored papers 2
Yale School of Public Health
Co-authored papers 2
Yale School of Public Health
Co-authored papers 2
Christian Medical College
Co-authored papers 2
Yale School of Public Health
Co-authored papers 2
College of Science & Industry Convergence, Ewha Womans University
Co-authored papers 2
Department of Microbial Pathogenesis Yale University New Haven
Co-authored papers 2
Yale School of Medicine
Co-authored papers 2
Yale School of Public Health
Co-authored papers 2
Yale University School of Medicine
Co-authored papers 2
Yale School of Public Health
Co-authored papers 2
Co-authored papers 1
Yale School of Medicine
Co-authored papers 1
Yale University School of Medicine
Co-authored papers 1
Trinity College Dublin
Co-authored papers 1
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