Author details

Full Name

James A Pippin

Affiliation

Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia

ORCID

Career Start Year

1993

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37693606	3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity.	medRxiv	2024
36608130	Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep.	Sci Adv	2023
37662342	Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of <i>FAIM2</i>.	bioRxiv	2023
37736163	Patient-derived Colonoids From Disease-spared Tissue Retain Inflammatory Bowel Disease-specific Transcriptomic Signatures.	Gastro Hep Adv	2023
37645863	Perturbation of the insomnia <i>WDR90</i> GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, <i>PIG-Q</i>.	bioRxiv	2023
36070683	3D chromatin maps of the human pancreas reveal lineage-specific regulatory architecture of T2D risk.	Cell Metab	2022
35537191	Variant-to-gene-mapping analyses reveal a role for pancreatic islet cells in conferring genetic susceptibility to sleep-related traits.	Sleep	2022
35659055	Implicating effector genes at COVID-19 GWAS loci using promoter-focused Capture-C in disease-relevant immune cell types.	Genome Biol	2022
33069917	Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease.	Cell Mol Gastroenterol Hepatol	2021
33545232	3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders.	Prog Neurobiol	2021
33608451	Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/Î²-Catenin Signaling through Enhanced Smad4-LEF1 Binding.	Mol Cancer Res	2021
34799566	Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits.	Nat Commun	2021
34532616	CRISPR-Cas9-Mediated Genome Editing Confirms <i>EPDR1</i> as an Effector Gene at the BMD GWAS-Implicated '<i>STARD3NL</i>' Locus.	JBMR Plus	2021
33459256	Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci.	Elife	2021
33397451	Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual.	Genome Biol	2021
32620744	Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells.	Nat Commun	2020
30890710	Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density.	Nat Commun	2019
23007710	Dual ErbB1 and ErbB2 receptor tyrosine kinase inhibition exerts synergistic effect with conventional chemotherapy in pancreatic cancer.	Oncol Rep	2012
18521697	Targeted suppression of beta-catenin blocks intestinal adenoma formation in APC Min mice.	J Gastrointest Surg	2008
14752418	Down-regulation of beta catenin inhibits the growth of esophageal carcinoma cells.	J Thorac Cardiovasc Surg	2004
11522655	Suppression of beta-catenin inhibits the neoplastic growth of APC-mutant colon cancer cells.	Cancer Res	2001
11676549	Beta-catenin antisense treatment decreases beta-catenin expression and tumor growth rate in colon carcinoma xenografts.	J Surg Res	2001
10676637	Down-regulation of HER2/neu expression induces apoptosis in human cancer cells that overexpress HER2/neu.	Cancer Res	2000
10898188	Antisense oligonucleotides: an evolving technology for the modulation of gene expression in human disease.	J Am Coll Surg	2000
11156527	HER2/neu antisense targeting of human breast carcinoma.	Oncogene	2000
10455915	Synergistic antitumor effects of HER2/neu antisense oligodeoxynucleotides and conventional chemotherapeutic agents.	Surgery	1999
9698539	Antisense oligonucleotides specific for the HER2/neu oncogene inhibit the growth of human breast carcinoma cells that overexpress HER2/neu.	J Surg Res	1998
8755619	Identification of a cDNA for a human high molecular-weight B-cell growth factor.	Proc Natl Acad Sci U S A	1996
8024789	An inexpensive method for the rapid identification of specific cDNAs from cDNA libraries.	Biotechniques	1994
8327514	Identification of a cDNA for a human high-molecular-weight B-cell growth factor.	Proc Natl Acad Sci U S A	1993

1 - 30 of 30

Yuelin J Zhu

National Cancer Institute, National Institutes of Health

Career Start Year 2002

Number of shared co-authors 0

Ru-Fang Yeh

Genentech Inc.

Career Start Year 1999

Number of shared co-authors 0

Jan Koster

Amsterdam University Medical Centers location AMC

Career Start Year 1999

Number of shared co-authors 1

Shawn Levy

HudsonAlpha Institute for Biotechnology

Career Start Year 1999

Number of shared co-authors 3

Yutaka Nakachi

Kumamoto University

Career Start Year 1997

Number of shared co-authors 0

Lianbo Yu

The Ohio State University

Career Start Year 1997

Number of shared co-authors 0

Robert L Walker

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1997

Number of shared co-authors 0

Dongquan Chen

University of Alabama at Birmingham

Career Start Year 1997

Number of shared co-authors 0

Qing-Rong Chen

Center for Biomedical Informatics and Information Technology

Career Start Year 1996

Number of shared co-authors 0

David Cogdell

The University of Texas MD Anderson Cancer Center

Career Start Year 1996

Number of shared co-authors 0

Agnes Viale

Memorial Sloan Kettering Cancer Center

Career Start Year 1996

Number of shared co-authors 0

Alexei Protopopov

The University of MD Anderson Cancer Center

Career Start Year 1995

Number of shared co-authors 0

Phillip Buckhaults

University of South Carolina

Career Start Year 1993

Number of shared co-authors 0

Yusuke Nakamura

Japanese Foundation for Cancer Research

Career Start Year 1992

Number of shared co-authors 2

Kevin G Becker

National Institute on Aging, National Institutes of Health

Career Start Year 1992

Number of shared co-authors 0

Loren Miraglia

Genomics Institute of the Novartis Research Foundation

Career Start Year 1991

Number of shared co-authors 0

Teresa L Johnson-Pais

University of Texas Health San Antonio

Career Start Year 1990

Number of shared co-authors 0

Abdel G Elkahloun

National Human Genome Research Institute

Career Start Year 1990

Number of shared co-authors 0

Sean M Grimmond

The University of Melbourne

Career Start Year 1990

Number of shared co-authors 1

Dirk Geerts

Amsterdam University Medical Center

Career Start Year 1989

Number of shared co-authors 0

Wei Zhang

The University of Texas MD Anderson Cancer Center

Career Start Year 1988

Number of shared co-authors 0

Mark A Watson

Washington University School of Medicine

Career Start Year 1987

Number of shared co-authors 0

Timothy C Burn

Incyte Research Institute

Career Start Year 1987

Number of shared co-authors 0

Martin J Walsh

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Career Start Year 1987

Number of shared co-authors 0

Eivind Hovig

Center for Bioinformatics, University of Oslo

Career Start Year 1987

Number of shared co-authors 0

Edison T Liu

USA The Jackson Laboratory Cancer Center

Career Start Year 1982

Number of shared co-authors 1

Richard M Myers

HudsonAlpha Institute for Biotechnology

Career Start Year 1980

Number of shared co-authors 3

Bruce J Aronow

Cincinnati Children's Hospital Medical Center

Career Start Year 1975

Number of shared co-authors 1

Sean Davis

Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington

Career Start Year 1974

Number of shared co-authors 1

Paul S Meltzer

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1970

Number of shared co-authors 0

row(s) 1 - 30 of 30

Struan F A Grant

Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia

Co-authored papers 17

Alessandra Chesi

Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia

Co-authored papers 14

Matthew C Pahl

Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia

Co-authored papers 13

Matthew E Johnson

Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia

Co-authored papers 10

Andrew D Wells

Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia

Co-authored papers 10

Sumei Lu

China National Center for Biotechnology Development

Co-authored papers 8

Michelle E Leonard

The Children's Hospital of Philadelphia

Co-authored papers 8

Yadav Wagley

Department of Orthopedic Surgery University of Michigan Medical School Ann Arbor

Co-authored papers 5

Diana L Cousminer

Children's Hospital of Philadelphia

Co-authored papers 5

Kurt D Hankenson

University of Michigan School of Medicine ann arbor

Co-authored papers 4

Elisabetta Manduchi

Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia

Co-authored papers 3

Babette S Zemel

Children's Hospital of Philadelphia

Co-authored papers 2

Klaus H Kaestner

Department of Genetics and Institute for Diabetes, University of Pennsylvania

Co-authored papers 2

Allan I Pack

University of Pennsylvania Perelman School of Medicine

Co-authored papers 2

Benjamin F Voight

Perelman School of Medicine, University of Pennsylvania

Co-authored papers 2

Gregory P Way

Broad Institute of MIT and Harvard

Co-authored papers 1

Jonathan P Bradfield

Co-authored papers 1

Vicente Gilsanz

Center for Endocrinology, Children's Hospital Los Angeles

Co-authored papers 1

Shana E McCormack

The Children's Hospital of Philadelphia Division of Endocrinology and Diabetes

Co-authored papers 1

April Hartley

MRC Integrative Epidemiology Unit at the University of Bristol

Co-authored papers 1

Jonathan A Mitchell

Perelman School of Medicine, University of Pennsylvania

Co-authored papers 1

Stewart A Anderson

Co-authored papers 1

Ahmed Elhakeem

Bristol Medical School, University of Bristol

Co-authored papers 1

Casey S Greene

Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine

Co-authored papers 1

Diego R Mazzotti

University of Kansas Medical Center

Co-authored papers 1

Andrea Kelly

The Children's Hospital of Philadelphia

Co-authored papers 1

Denis Baird

University of Bristol, Bristol Medical School

Co-authored papers 1

Laura D Howe

University of Bristol