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Author Details

Tom Maniatis
College des medecins du Quebec
1968
300
144
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36538032Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.Science2023
37632041Molecular and Clinical Epidemiology of SARS-CoV-2 Infection among Vaccinated and Unvaccinated Individuals in a Large Healthcare Organization from New Jersey.Viruses2023
37465737In solidarity with anti-racism leaders in Canadian medical education.Can Med Educ J2023
35997285Genomic Epidemiology and Serology Associated with a SARS-CoV-2 R.1 Variant Outbreak in New Jersey.mBio2022
34099552ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy.Proc Natl Acad Sci U S A2021
34431691Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment.mSphere2021
34787439Postvaccination SARS-COV-2 among Health Care Workers in New Jersey: A Genomic Epidemiological Study.Microbiol Spectr2021
32220666The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice.Neuron2020
32633719Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.Elife2020
32679536The role of clustered protocadherins in neurodevelopment and neuropsychiatric diseases.Curr Opin Genet Dev2020
30940688A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS.Genome Res2019
31748271Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity.Proc Natl Acad Sci U S A2019
31710891The generation of a protocadherin cell-surface recognition code for neural circuit assembly.Curr Opin Neurobiol2019
31650585Learning by teaching: benefits for frontline clinician-teachers.Med Educ2019
30955885Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice.Cell2019
30971825Visualization of clustered protocadherin neuronal self-recognition complexes.Nature2019
30296392Writing, Reading, and Translating the Clustered Protocadherin Cell Surface Recognition Code for Neural Circuit Assembly.Annu Rev Cell Dev Biol2018
30234475Mycophenolate Mofetil-Induced Status Epilepticus.Can J Neurol Sci2018
29986098Solid phase chemistry to covalently and reversibly capture thiolated RNA.Nucleic Acids Res2018
30111345Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons.Genome Biol2018
28743640Structural origins of clustered protocadherin-mediated neuronal barcoding.Semin Cell Dev Biol2017
28459448Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development.Nat Biotechnol2017
28450637Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly.Science2017
28450636Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice.Science2017
29087338Protocadherin <i>cis</i>-dimer architecture and recognition unit diversity.Proc Natl Acad Sci U S A2017
28904095Distinct roles for motor neuron autophagy early and late in the SOD1<sup>G93A</sup> mouse model of ALS.Proc Natl Acad Sci U S A2017
27371659Histone and DNA Modifications as Regulators of Neuronal Development and Function.Cold Spring Harb Perspect Biol2016
27782885γ-Protocadherin structural diversity and functional implications.Elife2016
27162329Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species.Proc Natl Acad Sci U S A2016
27161523Structural Basis of Diverse Homophilic Recognition by Clustered α- and β-Protocadherins.Neuron2016
25667251Resident duty-hour reform: moving beyond "change for change's sake".CMAJ2015
26276636CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function.Cell2015
26478182Molecular logic of neuronal self-recognition through protocadherin domain interactions.Cell2015
26039991hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function.Proc Natl Acad Sci U S A2015
25877220Astrocytes in neurodegenerative disease.Cold Spring Harb Perspect Biol2015
25700176Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.Science2015
24651281Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells.PLoS One2014
25561221Scheduling in the context of resident duty hour reform.BMC Med Educ2014
25171406Single-cell identity generated by combinatorial homophilic interactions between α, β, and γ protocadherins.Cell2014
25186741An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.J Neurosci2014
24507191Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.Neuron2014
23303937Accelerated high-yield generation of limb-innervating motor neurons from human stem cells.J Neurosci2013
23856579Unpicking neurodegeneration in a dish with human pluripotent stem cells: one cell type at a time.Cell Cycle2013
23850290A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.Cell Rep2013
23900538Clustered protocadherins.Development2013
23740897Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".Sci Transl Med2013
23388633Intricate interplay between astrocytes and motor neurons in ALS.Proc Natl Acad Sci U S A2013
23401527Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.Proc Natl Acad Sci U S A2013
23453971Crystal structure and mechanism of activation of TANK-binding kinase 1.Cell Rep2013
23524394Single-molecule imaging of transcription factor binding to DNA in live mammalian cells.Nat Methods2013
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Collaborators

HudsonAlpha Institute for Biotechnology
Co-authored papers 16
Columbia University Irving Medical Center
Co-authored papers 8
Zuckerman Mind Brain Behaviour Institute
Co-authored papers 7
Co-authored papers 6
Co-authored papers 6
Co-authored papers 5
Washington University School of Medicine
Co-authored papers 4
Co-authored papers 4
NYU Grossman School of Medicine
Co-authored papers 4
Broad Institute of Harvard and MIT
Co-authored papers 4
Drexel University
Co-authored papers 4
Co-authored papers 3
University of Michigan ann arbor
Co-authored papers 3
Merkin Institute for Translational Research, California Institute of Technology
Co-authored papers 3
J. David Gladstone Institutes
Co-authored papers 3
Center for Epigenomics, University of California San Diego
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Huntsman Cancer Institute, University of Utah
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Duke University
Co-authored papers 2
Co-authored papers 2
Yale School of Medicine
Co-authored papers 2
Duke University School of Medicine
Co-authored papers 2
Institute for Genomic Medicine, Columbia University Irving Medical Center
Co-authored papers 2
Harvard University, Howard Hughes Medical Institute, Harvard Stem Cell Institute
Co-authored papers 2
McGill University, Canada Montreal Neurological Institute and Hospital
Co-authored papers 2