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Author Details

David C Airey
Lilly Research Laboratories
2000
49
28
PMIDPaper TitleJournal TitlePublished Year
36918909Mechanism of action deconvolution of the small-molecule pathological tau aggregation inhibitor Anle138b.Alzheimers Res Ther2023
35177665A human tau seeded neuronal cell model recapitulates molecular responses associated with Alzheimer's disease.Sci Rep2022
33580742Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study.Alzheimers Dement2021
33924960Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer's Disease in Down Syndrome: Early Data from the Longitudinal Investigation for Enhancing Down Syndrome Research (LIFE-DSR) Study.J Clin Med2021
32246036Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease.Nat Commun2020
32668255Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.Cell Rep2020
29626426Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography.Alzheimers Dement2018
30558641Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.Mol Neurodegener2018
29778948Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABA<sub>A</sub> receptors: Improved bioavailability enhances anticonvulsant efficacy.Neuropharmacology2018
27723281Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab.Arthritis Rheumatol2017
28692710Association of Plasma Total Tau Level With Cognitive Decline and Risk of Mild Cognitive Impairment or Dementia in the Mayo Clinic Study on Aging.JAMA Neurol2017
26738766Genomic structure and expression of the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons.BMC Genet2016
27436677Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort.Alzheimers Dement2016
24090638Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function.Neurochem Int2014
24465413Angiotensin-induced abdominal aortic aneurysms in hypercholesterolemic mice: role of serum cholesterol and temporal effects of exposure.PLoS One2014
24405699Quantitative trait loci mapping and gene network analysis implicate protocadherin-15 as a determinant of brain serotonin transporter expression.Genes Brain Behav2014
24102824Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice.Genes Brain Behav2014
22798947Use of flow cytometry for high-throughput cell population estimates in brain tissue.Front Neuroanat2012
20300202A rapid and reliable method of counting neurons and other cells in brain tissue: a comparison of flow cytometry and manual counting methods.Front Neuroanat2010
20798050Neuron densities vary across and within cortical areas in primates.Proc Natl Acad Sci U S A2010
20582266Impact of RNA editing on functions of the serotonin 2C receptor in vivo.Front Neurosci2010
20181818High-throughput multiplexed transcript analysis yields enhanced resolution of 5-hydroxytryptamine 2C receptor mRNA editing profiles.Mol Pharmacol2010
20165943The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen.Psychopharmacology (Berl)2010
19154337RNA editing of the serotonin 2C receptor and expression of Galpha(q) protein: genetic mouse models do not support a role for regulation or compensation.J Neurochem2009
20582282Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource.Front Neurosci2009
19336545Heritable variation of ERBB2 and breast cancer risk.Cancer Epidemiol Biomarkers Prev2009
19179283Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes.Proc Natl Acad Sci U S A2009
18431467Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis.PLoS One2008
18817551Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight.BMC Genomics2008
19015382Centennial perspective: serotonin receptors.Mol Interv2008
16697352Polymorphisms in the regulatory region of the human serotonin 5-HT2A receptor gene (HTR2A) influence gene expression.Biol Psychiatry2007
165807575-HT(2C) receptor RNA editing in the amygdala of C57BL/6J, DBA/2J, and BALB/cJ mice.Neurosci Res2006
16978410Geometric morphometrics defines shape differences in the cortical area map of C57BL/6J and DBA/2J inbred mice.BMC Neurosci2006
15774010Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity.BMC Neurosci2005
15917433A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts.Mol Pharmacol2005
15879512Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations.Genetics2005
16104382Quantitative trait mapping in a diallel cross of recombinant inbred lines.Mamm Genome2005
15514660The Collaborative Cross, a community resource for the genetic analysis of complex traits.Nat Genet2004
15294878Interactions between Sox10 and EdnrB modulate penetrance and severity of aganglionosis in the Sox10Dom mouse model of Hirschsprung disease.Hum Mol Genet2004
12655329Inappropriate choice of the experimental unit leads to a dramatic overestimation of the significance of quantitative trait loci for prepulse inhibition and startle response in recombinant congenic mice.Neuropsychopharmacology2003
12879962Genetic sources of individual differences in the cerebellum.Cerebellum2002
11438585Genetic control of the mouse cerebellum: identification of quantitative trait loci modulating size and architecture.J Neurosci2001
11331379Complex trait analysis of the hippocampus: mapping and biometric analysis of two novel gene loci with specific effects on hippocampal structure in mice.J Neurosci2001
11529276Genetic dissection of the olfactory bulbs of mice: QTLs on four chromosomes modulate bulb size.Behav Genet2001
10775496Differences in the complexity of song tutoring cause differences in the amount learned and in dendritic spine density in a songbird telencephalic song control nucleus.Neurobiol Learn Mem2000
11416915Variation in the volume of zebra finch song control nuclei is heritable: developmental and evolutionary implications.Proc Biol Sci2000
10923697Greater song complexity is associated with augmented song system anatomy in zebra finches.Neuroreport2000
10880127Song, sexual selection, and a song control nucleus (HVc) in the brains of European sedge warblers.J Neurobiol2000
10852237Greater song complexity is associated with augmented song system anatomy in zebra finches.Neuroreport2000
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Collaborators

University of Tennessee Health Science Center
Co-authored papers 13
Mayo Clinic
Co-authored papers 12
Institute of Psychiatry, King's College London
Co-authored papers 4
Mayo Clinic Rochester
Co-authored papers 3
Mayo Clinic Rochester
Co-authored papers 3
Mayo Clinic
Co-authored papers 3
Baylor College of Medicine
Co-authored papers 3
Center for Systems Neurogenetics of Addiction at The Jackson Laboratory
Co-authored papers 3
Mayo Clinic Rochester
Co-authored papers 3
McMaster University & St. Joseph's Healthcare Hamilton
Co-authored papers 2
University of Essex
Co-authored papers 2
Tufts University
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Fred Hutchinson Cancer Research Center
Co-authored papers 2
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
College Station
Co-authored papers 2
Institute for Cell Engineering, Johns Hopkins University School of Medicine
Co-authored papers 1
University of North Carolina at Chapel Hill
Co-authored papers 1
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 1
Institute for Systems Biology
Co-authored papers 1
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 1
University of North Carolina
Co-authored papers 1
Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Emory University School of Medicine
Co-authored papers 1
Institute for Systems Biology
Co-authored papers 1
Rush University Medical Center
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
University of British Columbia and BC Children's Hospital
Co-authored papers 1
Lilly Research Laboratories
Co-authored papers 1