Author details

Full Name

Michal Mrug

Affiliation

ORCID

Career Start Year

1993

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36457161	A kidney resident macrophage subset is a candidate biomarker for renal cystic disease in preclinical models.	Dis Model Mech	2023
37729939	Polycystic Kidney Disease Diet: What is Known and What is Safe.		2023
37256130	<i>Cx3cr1</i> controls kidney resident macrophage heterogeneity.	Front Immunol	2023
37217845	Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion.	Mol Med	2023
36794756	Accuracy and processing time of kidney volume measurement methods in rodents polycystic kidney disease models: superiority of semiautomated kidney segmentation.	Am J Physiol Renal Physiol	2023
36736536	Utility of new image-derived biomarkers for autosomal dominant polycystic kidney disease prognosis using automated instance cyst segmentation.		2023
36535535	Venglustat, a Novel Glucosylceramide Synthase Inhibitor, in Patients at Risk of Rapidly Progressing ADPKD: Primary Results of a Double-Blind, Placebo-Controlled, Phase 2/3 Randomized Clinical Trial.		2023
36176661	Design and Basic Characteristics of a National Patient-Powered Registry in ADPKD.		2022
35217526	Volume Progression and Imaging Classification of Polycystic Liver in Early Autosomal Dominant Polycystic Kidney Disease.	Clin J Am Soc Nephrol	2022
35110364	A Comprehensive Immune Cell Atlas of Cystic Kidney Disease Reveals the Involvement of Adaptive Immune Cells in Injury-Mediated Cyst Progression in Mice.	J Am Soc Nephrol	2022
34890546	Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype.	Am J Hum Genet	2022
36204243	The STAGED-PKD 2-Stage Adaptive Study With a Patient Enrichment Strategy and Treatment Effect Modeling for Improved Study Design Efficiency in Patients With ADPKD.	Kidney Medicine	2022
33912745	Prognostic Value of Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease.	Kidney Int Rep	2021
35373094	Autosomal Dominant Polycystic Kidney Disease Does Not Significantly Alter Major COVID-19 Outcomes among Veterans.		2021
34939014	Genetic Testing for Chronic Kidney Diseases: Clinical Utility and Barriers Perceived by Nephrologists.	Kidney Medicine	2021
34396149	Ly6c<sup>hi</sup> Infiltrating Macrophages Promote Cyst Progression in Injured Conditional <i>Ift88</i> Mice.	Kidney360	2021
34158590	Early infiltrating macrophage subtype correlates with late-stage phenotypic outcome in a mouse model of hepatorenal fibrocystic disease.	Lab Invest	2021
32325183	Role of chemokines, innate and adaptive immunity.	Cellular Signalling	2020
33490963	Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease.	Kidney360	2020
33269373	Autosomal Dominant Polycystic Kidney Disease does not significantly alter major COVID-19 outcomes among veterans.		2020
32634120	The value of genotypic and imaging information to predict functional and structural outcomes in ADPKD.	JCI Insight	2020
31337691	Tissue-Resident Macrophages Promote Renal Cystic Disease.	J Am Soc Nephrol	2019
31088850	Growth Pattern of Kidney Cyst Number and Volume in Autosomal Dominant Polycystic Kidney Disease.	Clin J Am Soc Nephrol	2019
30948627	Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species.	J Am Soc Nephrol	2019
30922668	Long-term trajectory of kidney function in autosomal-dominant polycystic kidney disease.	Kidney Int	2019
30674729	Resident macrophages reprogram toward a developmental state after acute kidney injury.	JCI Insight	2019
30632307	Urinary T cells correlate with rate of renal function loss in autosomal dominant polycystic kidney disease.	Physiol Rep	2019
30600684	Heterozygous Pkhd1<sup>C642*</sup> mice develop cystic liver disease and proximal tubule ectasia that mimics radiographic signs of medullary sponge kidney.	Am J Physiol Renal Physiol	2019
30566001	Truncating PKHD1 and PKD2 mutations alter energy metabolism.	Am J Physiol Renal Physiol	2019
30133325	Mks6 mutations reveal tissue- and cell type-specific roles for the cilia transition zone.	FASEB J	2019
31631001	Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease.		2019
31444870	Sodium and potassium excretion predict increased depression in urban adolescents.	Physiological Reports	2019
31361604	Crystal deposition triggers tubule dilation that accelerates cystogenesis in polycystic kidney disease.	Journal of Clinical Investigation	2019
29290310	Baseline total kidney volume and the rate of kidney growth are associated with chronic kidney disease progression in Autosomal Dominant Polycystic Kidney Disease.	Kidney Int	2018
30591038	Relationship between caffeine intake and autosomal dominant polycystic kidney disease progression: a retrospective analysis using the CRISP cohort.	BMC Nephrol	2018
30228150	A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan.	J Am Soc Nephrol	2018
29537311	Casein kinase 1Îµ and 1Î± as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.		2018
28027795	Performance of the CKD-EPI Equation to Estimate GFR in a Longitudinal Study of Autosomal Dominant Polycystic Kidney Disease.	Am J Kidney Dis	2017
28532709	Image texture features predict renal function decline in patients with autosomal dominantÂ polycystic kidney disease.	Kidney Int	2017
28491318	Recovery of methotrexate-induced anuric acute kidney injury after glucarpidase therapy.	SAGE Open Medical Case Reports	2017
28317621	Uric Acid Excretion Predicts Increased Blood Pressure Among American Adolescents of African Descent.		2017
26797708	Automated Segmentation of Kidneys from MR Images in Patients with Autosomal Dominant Polycystic Kidney Disease.	Clin J Am Soc Nephrol	2016
27779124	Automated segmentation of liver and liver cysts from bounded abdominal MR images in patients with autosomal dominant polycystic kidney disease.	Phys Med Biol	2016
27599120	International Multi-Specialty Delphi Survey: Identification of Diagnostic Criteria for Hepatic and Renal Cyst Infection.	Nephron	2016
27180134	Uric acid excretion predicts increased aggression in urban adolescents.	Physiology and Behavior	2016
26823553	Predicted Mutation Strength of Nontruncating PKD1 Mutations Aids Genotype-Phenotype Correlations in Autosomal Dominant Polycystic Kidney Disease.	J Am Soc Nephrol	2016
24904092	Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials.	J Am Soc Nephrol	2015
26295839	Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse.	PLoS One	2015
25830764	A comparison of ultrasound and magnetic resonance imaging shows that kidney length predicts chronic kidney disease in autosomal dominant polycystic kidney disease.	Kidney International	2015
24576800	Novel methodology to evaluate renal cysts in polycystic kidney disease.	Am J Nephrol	2014