Author details

Full Name

Brigham H Mecham

Affiliation

Center for Cancer Innovation, University of Washington

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
35294224	Safety, Feasibility, and Merits of Longitudinal Molecular Testing of Multiple Metastatic Sites to Inform mTNBC Patient Treatment in the Intensive Trial of Omics in Cancer.	JCO Precis Oncol	2022
32160771	Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload-Induced Heart Failure.	Circ Heart Fail	2020
28585545	Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.	Nat Commun	2017
28205517	Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.	Nat Commun	2017
28615356	Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes.	Sci Transl Med	2017
26733551	A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer.	J Natl Compr Canc Netw	2016
27340017	Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.	Nat Commun	2016
25753363	Osteoblast differentiation profiles define sex specific gene expression patterns in craniosynostosis.	Bone	2015
26188427	Transcriptional analysis of human cranial compartments with different embryonic origins.	Arch Oral Biol	2015
24623855	Derivation of naive human embryonic stem cells.	Proc Natl Acad Sci U S A	2014
25105228	Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis.	Am J Hum Genet	2014
23493267	PPP2R2C loss promotes castration-resistance and is associated with increased prostate cancer-specific mortality.	Mol Cancer Res	2013
24092238	MyoD is a tumor suppressor gene in medulloblastoma.	Cancer Res	2013
23995691	A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.	Nature	2013
23596205	Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.	Sci Transl Med	2013
23671412	Improving breast cancer survival analysis through competition-based multidimensional modeling.	PLoS Comput Biol	2013
22869526	A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse model.	Mol Cell Biol	2012
23073384	Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation.	Physiol Genomics	2012
22028906	Differential expression of extracellular matrix-mediated pathways in single-suture craniosynostosis.	PLoS One	2011
20363728	Supervised normalization of microarrays.	Bioinformatics	2010
18664640	Expression profiles of the mouse lung identify a molecular signature of time-to-birth.	Am J Respir Cell Mol Biol	2009
19341625	Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells.	Cell Stem Cell	2009
19223557	Conserved gene expression programs integrate mammalian prostate development and tumorigenesis.	Cancer Res	2009
17577413	Genetic background influences murine prostate gene expression: implications for cancer phenotypes.	Genome Biol	2007
17923522	Individual matrix metalloproteinases control distinct transcriptional responses in airway epithelial cells infected with Pseudomonas aeruginosa.	Infect Immun	2007
16358219	The SERPINE2 gene is associated with chronic obstructive pulmonary disease.	Am J Hum Genet	2006
16794260	Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells.	Am J Respir Cell Mol Biol	2006
15850491	Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements.	BMC Bioinformatics	2005
15161944	Sequence-matched probes produce increased cross-platform consistency and more reproducible biological results in microarray-based gene expression measurements.	Nucleic Acids Res	2004
15161964	Increased measurement accuracy for sequence-verified microarray probes.	Physiol Genomics	2004
12475896	A variable fold change threshold determines significance for expression microarrays.	FASEB J	2003

1 - 31 of 31

Wayne Yu

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University

Career Start Year 2005

Number of shared co-authors 0

Steffen Durinck

Genentech Inc.

Career Start Year 2004

Number of shared co-authors 1

James W MacDonald

University of Washington

Career Start Year 2003

Number of shared co-authors 0

Leslie Cope

Johns Hopkins University School of Medicine

Career Start Year 2003

Number of shared co-authors 0

Mark Reimers

Institute for Quantitative Health Science and Engineering, Michigan State University

Career Start Year 2002

Number of shared co-authors 0

Joel S Parker

Lineberger Cancer Center, University of North Carolina

Career Start Year 2002

Number of shared co-authors 8

Charles J Tucker

National Institute of Environmental Health Sciences, National Institutes of Health

Career Start Year 2002

Number of shared co-authors 1

Sami Kilpinen

University of Helsinki

Career Start Year 2002

Number of shared co-authors 1

Jean Yee Hwa Yang

The University of Sydney

Career Start Year 2001

Number of shared co-authors 0

Rafael A Irizarry

Dana-Farber Cancer Institute

Career Start Year 2001

Number of shared co-authors 0

Winston Patrick Kuo

Harvard School of Dental Medicine

Career Start Year 2001

Number of shared co-authors 1

Mikhail G Dozmorov

Virginia Commonwealth University

Career Start Year 2001

Number of shared co-authors 0

Gregory R Grant

Perelman School of Medicine, University of Pennsylvania Philadelphia

Career Start Year 1999

Number of shared co-authors 0

Shawn Levy

HudsonAlpha Institute for Biotechnology

Career Start Year 1999

Number of shared co-authors 4

Christina Kendziorski

University of Wisconsin-Madison

Career Start Year 1999

Number of shared co-authors 2

Paul T Spellman

Oregon Health & Science University Hospital.

Career Start Year 1998

Number of shared co-authors 7

Peter A C 't Hoen

Radboud University Medical Center

Career Start Year 1998

Number of shared co-authors 3

Shannon K McWeeney

Oregon Health & Science University, University of California Berkeley

Career Start Year 1997

Number of shared co-authors 4

Benedikt Brors

German Cancer Research Center (DKFZ)

Career Start Year 1997

Number of shared co-authors 4

Wolfgang Huber

Technische Universitat Munchen

Career Start Year 1995

Number of shared co-authors 3

Gary Hardiman

Institute for Global Food Security, Queen's University Belfast

Career Start Year 1994

Number of shared co-authors 0

Yidong Chen

Zhujiang Hospital, Southern Medical University

Career Start Year 1993

Number of shared co-authors 0

Gordon K Smyth

The University of Melbourne

Career Start Year 1992

Number of shared co-authors 1

Keith A Baggerly

The University of Texas MD Anderson Cancer Center

Career Start Year 1991

Number of shared co-authors 1

Kevin R Coombes

Medical College of Georgia

Career Start Year 1990

Number of shared co-authors 3

Sean M Grimmond

The University of Melbourne

Career Start Year 1990

Number of shared co-authors 2

John Quackenbush

Harvard T. H. Chan School of Public Health

Career Start Year 1989

Number of shared co-authors 5

Luigi Marchionni

Weill-Cornell School of Medicine

Career Start Year 1989

Number of shared co-authors 0

Bruce J Aronow

Cincinnati Children's Hospital Medical Center

Career Start Year 1975

Number of shared co-authors 7

Paul C Boutros

University of California los angeles

Career Start Year 1970

Number of shared co-authors 16

row(s) 1 - 30 of 30

Isaac S Kohane

Harvard Medical School

Co-authored papers 5

Colin C Pritchard

University of Washington, USA Brotman Baty Institute for Precision Medicine

Co-authored papers 4

Peter S Nelson

Fred Hutchinson Cancer Center

Co-authored papers 4

Carl Anthony Blau

Center for Cancer Innovation, University of Washington

Co-authored papers 4

Gaurav Pandey

Sanjay Gandhi Post Graduate Institute of Medical Sciences

Co-authored papers 4

Stephen H Friend

University of Oxford

Co-authored papers 3

Ilsa Coleman

Fred Hutchinson Cancer Center

Co-authored papers 3

Janusz Dutkowski

Data4Cure Inc.

Co-authored papers 3

Lara M Mangravite

Children's Hospital Oakland Research Institute

Co-authored papers 3

Carlos Caldas

Cancer Research UK Cambridge Institute, University of Cambridge

Co-authored papers 2

Anne-Lise B??rresen-Dale

Institute for Cancer Research, Oslo University Hospital

Co-authored papers 2

Valentin Fuster

Co-authored papers 2

Jason C Kovacic

Co-authored papers 2

Anders H Rosengren

Co-authored papers 2

Gwendalyn J Randolph

Co-authored papers 2

Aya Nomura-Kitabayashi

Co-authored papers 2

Michael O Dorschner

University of Washington

Co-authored papers 2

Christina Curtis

Stanford University School of Medicine

Co-authored papers 2

Eric P Kaldjian

Co-authored papers 2

Claes B Wollheim

Lund University

Co-authored papers 2

Vessela N Kristensen

Faculty of Clinical Medicine, University of Oslo

Co-authored papers 2

Joshua D Smith

University of Washington

Co-authored papers 2

Deborah A Nickerson

University of Washington

Co-authored papers 2

Oscar M Rueda

University of Cambridge

Co-authored papers 2

Gustavo Stolovitzky

IBM T.J. Watson Research Center

Co-authored papers 2

Jingchun Zhu

University of California at Santa Cruz

Co-authored papers 2

Adam A Margolin

Icahn School of Medicine

Co-authored papers 2

James M Olson

Clinical Research Division, Fred Hutchinson Cancer Center

Co-authored papers 2

Hans Kristian Moen Vollan

F Hoffmann-La Roche Ltd

Co-authored papers 2

1 - 30

Author Details

Column Actions

Recommended Authors

Collaborators