Author details

Full Name

Connie R Jimenez

Affiliation

ORCID

Career Start Year

1992

Papers

218

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36916528	Advancing wide implementation of precision oncology: A liquid nitrogen-free snap freezer preserves molecular profiles of biological samples.		2023
37940875	Candidate biomarkers for treatment benefit from sunitinib in patients with advanced renal cell carcinoma using mass spectrometry-based (phospho)proteomics.		2023
37665466	Phosphoproteomics After Guanidinium Thiocyanate Extraction of Tissue Biopsies.		2023
37665463	A Robust and Clinically Applicable Sample Preparation Protocol for Urinary Extracellular Vesicle Isolation Suitable for Mass Spectrometry-Based Proteomics.		2023
37585503	Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer.	Sci Transl Med	2023
37477020	EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy.		2023
36906835	A transformer architecture for retention time prediction in liquid chromatography mass spectrometry-based proteomics.		2023
37280612	Atrial epicardial adipose tissue abundantly secretes myeloperoxidase and activates atrial fibroblasts in patients with atrial fibrillation.		2023
37209095	Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors.	Cell Rep	2023
37023079	C1q is increased in cerebrospinal fluid-derived extracellular vesicles in Alzheimer's disease: A multi-cohort proteomics and immuno-assay validation study.		2023
37269289	Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma.		2023
36639418	Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma.	Commun Biol	2023
37454217	Potential diagnostic value of CSF metabolism-related proteins across the Alzheimer's disease continuum.		2023
37521047	DPHL v.2: An updated and comprehensive DIA pan-human assay library for quantifying more than 14,000 proteins.	Patterns (N Y)	2023
35081007	Epigenetic Modification of the von Willebrand Factor Promoter Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension.	American Journal of Respiratory and Critical Care Medicine	2022
36369736	Integration of stool microbiota, proteome and amino acid profiles to discriminate patients with adenomas and colorectal cancer.	Gut Microbes	2022
36156810	Inferring kinase activity from phosphoproteomic data: Tool comparison and recent applications.	Mass Spectrometry Reviews	2022
35863698	Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines.	Molecular and Cellular Proteomics	2022
35984965	Donor natural killer cells trigger production of Î²-2-microglobulin to enhance post-bone marrow transplant immunity.	Blood	2022
35606362	Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy.	Nature Communications	2022
36409073	The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum.	mBio	2022
36255265	Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3.	ACS Chemical Biology	2022
36050473	Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.	Nature	2022
35217681	Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies.	Nature Communications	2022
35165100	Tumor Drug Concentration and Phosphoproteomic Profiles After Two Weeks of Treatment With Sunitinib in Patients with Newly Diagnosed Glioblastoma.	Clinical Cancer Research	2022
35130834	Secreted protein markers in oral squamous cell carcinoma (OSCC).	Clin Proteomics	2022
34361002	Effects of Cancer Presence and Therapy on the Platelet Proteome.	International Journal of Molecular Sciences	2021
33968084	Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After Î±2-3-Linked Sialic Acid Ligand Binding.	Frontiers in Immunology	2021
33750427	Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma.	J Exp Clin Cancer Res	2021
33587312	Lipopolysaccharide-regulated secretion of soluble and vesicle-based proteins from a panel of colorectal cancer cell lines.	Proteomics Clin Appl	2021
33536523	Neutrophil degranulation interconnects over-represented biological processes in atrial fibrillation.	Scientific Reports	2021
34280333	Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening : A Diagnostic Test Accuracy Study.	Ann Intern Med	2021
34272386	Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies.	Nature Communications	2021
33890711	Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.	EMBO Rep	2021
33732734	Sex-Related Differences in Protein Expression in Sarcomere Mutation-Positive Hypertrophic Cardiomyopathy.	Front Cardiovasc Med	2021
33459596	Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells.	eLife	2021
33561558	The influence of delay in mononuclear cell isolation on acute myeloid leukemia phosphorylation profiles.	Journal of Proteomics	2021
34035881	Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles.	J Extracell Vesicles	2021
33602116	Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients.	Clinical Proteomics	2021
34136754	Phosphoproteomic Characterization of Primary AML Samples and Relevance for Response Toward FLT3-inhibitors.	HemaSphere	2021
33819647	Feasibility of Phosphoproteomics on Leftover Samples After RNA Extraction With Guanidinium Thiocyanate.	Mol Cell Proteomics	2021
34341426	Longitudinal stability of urinary extracellular vesicle protein patterns within and between individuals.	Scientific Reports	2021
33307249	Feasibility of phosphoproteomics to uncover oncogenic signalling in secreted extracellular vesicles using glioblastoma-EGFRVIII cells as a model.	Journal of Proteomics	2021
32875713	Computational Analysis of Phosphoproteomics Data in Multi-Omics Cancer Studies.	Proteomics	2021
33341450	Quantitative analysis of CDX2 protein expression improves its clinical utility as a prognostic biomarker in stage II and III colon cancer.	Eur J Cancer	2021
33430602	Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy.	Circ Heart Fail	2021
34675268	Simple urine storage protocol for extracellular vesicle proteomics compatible with at-home self-sampling.	Sci Rep	2021
34717701	High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer.	Journal of Experimental and Clinical Cancer Research	2021
31411736	Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression.	Int J Cancer	2020
32024067	Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome.	Cancers (Basel)	2020