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Author Details

Paul Pavlidis
University of British Columbia
1994
151
60
PMIDPaper TitleJournal TitlePublished Year
37918557SETD1A variant-associated psychosis: A systematic review of the clinical literature and description of two new cases.Prog Neuropsychopharmacol Biol Psychiatry2024
37308292Characterizing the targets of transcription regulators by aggregating ChIP-seq and perturbation expression data sets.Genome Res2023
37484885Open science in play and in tension with patent protections.J Law Biosci2023
33308442Multi-parametric analysis of 57 SYNGAP1 variants reveal impacts on GTPase signaling, localization, and protein stability.Am J Hum Genet2021
33599246Curation of over 10â¿¿000 transcriptomic studies to enable data reuse.Database (Oxford)2021
33746712Estimating and Correcting for Off-Target Cellular Contamination in Brain Cell Type Specific RNA-Seq Data.Front Mol Neurosci2021
34665801Experiment level curation of transcriptional regulatory interactions in neurodevelopment.PLoS Comput Biol2021
34475469Evaluation of connectivity map shows limited reproducibility in drug repositioning.Sci Rep2021
34354131"Guilt by association" is not competitive with genetic association for identifying autism risk genes.Sci Rep2021
32341540Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons.Nat Neurosci2020
32032513The Canadian Rare Diseases Models and Mechanisms (RDMM) Network: Connecting Understudied Genes to Model Organisms.Am J Hum Genet2020
31754030Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation.Proc Natl Acad Sci U S A2020
33124981A low affinity <i>cis</i>-regulatory BMP response element restricts target gene activation to subsets of Drosophila neurons.Elife2020
32580998Untangling the effects of cellular composition on coexpression analysis.Genome Res2020
32350270Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.Nat Commun2020
30846554Predictability of human differential gene expression.Proc Natl Acad Sci U S A2019
31767574Mega-Analysis of Gene Expression in Mouse Models of Alzheimer's Disease.eNeuro2019
31705629VariCarta: A Comprehensive Database of Harmonized Genomic Variants Found in Autism Spectrum Disorder Sequencing Studies.Autism Res2019
29982380Differential coexpression in human tissues and the confounding effect of mean expression levels.Bioinformatics2019
31211786Transcriptomic correlates of electrophysiological and morphological diversity within and across excitatory and inhibitory neuron classes.PLoS Comput Biol2019
31038196Whole genome sequencing and variant discovery in the ASPIRE autism spectrum disorder cohort.Clin Genet2019
29344313DNA methylation as a predictor of fetal alcohol spectrum disorder.Clin Epigenetics2018
30107399Monitoring changes in the Gene Ontology and their impact on genomic data analysis.Gigascience2018
30153812Systematic evaluation of isoform function in literature reports of alternative splicing.BMC Genomics2018
30177255Transcriptomic Evidence for Alterations in Astrocytes and Parvalbumin Interneurons in Subjects With Bipolar Disorder and Schizophrenia.Biol Psychiatry2018
29925830C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.Nat Commun2018
30349457Assessing Transcriptome Quality in Patch-Seq Datasets.Front Mol Neurosci2018
29357465Modeling sources of interlaboratory variability in electrophysiological properties of mammalian neurons.J Neurophysiol2018
27993773EGAD: ultra-fast functional analysis of gene networks.Bioinformatics2017
28385878Protease-Inhibitor Interaction Predictions: Lessons on the Complexity of Protein-Protein Interactions.Mol Cell Proteomics2017
28204549Using predictive specificity to determine when gene set analysis is biologically meaningful.Nucleic Acids Res2017
29204516Cross-Laboratory Analysis of Brain Cell Type Transcriptomes with Applications to Interpretation of Bulk Tissue Data.eNeuro2017
28979163A p53-regulated apoptotic gene signature predicts treatment response and outcome in pediatric acute lymphoblastic leukemia.Cancer Manag Res2017
29069078Transcriptomic correlates of neuron electrophysiological diversity.PLoS Comput Biol2017
28748932Can we predict protein from mRNA levels?Nature2017
26996386Meta-Analysis of Gene Expression Patterns in Animal Models of Prenatal Alcohol Exposure Suggests Role for Protein Synthesis Inhibition and Chromatin Remodeling.Alcohol Clin Exp Res2016
26647175Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: A potential treatment target?Mol Genet Metab2016
27604469An expanded evaluation of protein function prediction methods shows an improvement in accuracy.Genome Biol2016
27358653DNA methylation signature of human fetal alcohol spectrum disorder.Epigenetics Chromatin2016
27158917Interactive Exploration, Analysis, and Visualization of Complex Phenome-Genome Datasets with ASPIREdb.Hum Mutat2016
26889207Profiling placental and fetal DNA methylation in human neural tube defects.Epigenetics Chromatin2016
26989148Wikidata as a semantic framework for the Gene Wiki initiative.Database (Oxford)2016
25332401Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events.Nucleic Acids Res2015
26106167Metaanalysis of flawed expression profiling data leading to erroneous Parkinson's biomarker identification.Proc Natl Acad Sci U S A2015
26238605Transcriptome sequencing of the anterior cingulate in bipolar disorder: dysregulation of G protein-coupled receptors.Am J Psychiatry2015
26052282Text mining for neuroanatomy using WhiteText with an updated corpus and a new web application.Front Neuroinform2015
26010509The path of no return--Truncated protein N-termini and current ignorance of their genesis.Proteomics2015
25684047Prenatal alcohol exposure alters steady-state and activated gene expression in the adult rat brain.Alcohol Clin Exp Res2015
25720351Meta-Analysis of Gene Expression in Autism Spectrum Disorder.Autism Res2015
25432320Expansion of the QARS deficiency phenotype with report of a family with isolated supratentorial brain abnormalities.Neurogenetics2015
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Collaborators

Jesse Gillis
Stanley Institute for Cognitive Genomics
Co-authored papers 21
William Stafford Noble
Co-authored papers 8
Shreejoy J Tripathy
University of Toronto
Co-authored papers 8
Ryan T Demmer
University of Minnesota, Mailman School of Public Health Columbia University
Co-authored papers 7
Christopher M Overall
University of British Columbia
Co-authored papers 6
Nikolaus Fortelny
University of Salzburg
Co-authored papers 6
John J Mann
Columbia University College of Physicians and Surgeons
Co-authored papers 4
Bruce J Aronow
Cincinnati Children's Hospital Medical Center
Co-authored papers 4
Raymond S Lim
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Robert A Colbert
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Co-authored papers 3
Wyeth W Wasserman
BC Children's Hospital Research Institute, University of British Columbia
Co-authored papers 3
Adriana E Sede??o-Cort??s
Allen Institute for Brain Science
Co-authored papers 3
Gustavo Turecki
Douglas Institute, McGill University
Co-authored papers 3
Michael S Kobor
University of British Columbia
Co-authored papers 3
David N Glass
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Guy A Rouleau
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Carolyn Ch'ng
GenomeDx Biosciences Inc.
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Mallar Chakravarty
McGill University
Co-authored papers 2
Ali G Gharavi
Columbia University College of Physicians and Surgeons
Co-authored papers 2
Steven A Siegelbaum
Columbia University
Co-authored papers 2
Joy Hirsch
Yale School of Medicine
Co-authored papers 2
Vivette D D'Agati
Columbia University Irving Medical Center
Co-authored papers 2
Cristiana Cruceanu
Max Plank Institute for Psychiatry.
Co-authored papers 2
Cristina R Antonescu
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Yves A Lussier
Center for Biomedical Informatics and Biostatistics, University of Arizona
Co-authored papers 2
Christopher Funk
University of Colorado School of Medicine
Co-authored papers 1
Shanshan Zhang
Temple University
Co-authored papers 1
Lynn M Schriml
University of Maryland School of Medicine, Institute for Genome Sciences
Co-authored papers 1
Marina Marcet-Houben
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Release 1.2