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Author Details

Shirley M Taylor
Massey Cancer Center
1978
38
25
PMIDPaper TitleJournal TitlePublished Year
29051323Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM.Clin Cancer Res2018
26859456Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination.Cancer Cell2016
26385560p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb.Mol Cancer Res2016
26053857Epigenetic Modifications of the PGC-1α Promoter during Exercise Induced Expression in Mice.PLoS One2015
24532667Humanizing mouse folate metabolism: conversion of the dual-promoter mouse folylpolyglutamate synthetase gene to the human single-promoter structure.FASEB J2014
25164808Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain the subcellular compartmentalization of folates.J Biol Chem2014
21321201DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria.Proc Natl Acad Sci U S A2011
19211312In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation.DNA Repair (Amst)2009
17998333A mouse gene that coordinates epigenetic controls and transcriptional interference to achieve tissue-specific expression.Mol Cell Biol2008
17279620Probing the mechanism of the hamster mitochondrial folate transporter by mutagenesis and homology modeling.Biochemistry2007
17022734Early genetic changes involved in low-grade astrocytic tumor development.Curr Mol Med2006
15140890A mutation inactivating the mitochondrial inner membrane folate transporter creates a glycine requirement for survival of chinese hamster cells.J Biol Chem2004
14583449p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding.Cancer Res2003
10964921Expression patterns of the multiple transcripts from the folylpolyglutamate synthetase gene in human leukemias and normal differentiated tissues.J Biol Chem2000
10626793Tissue-specific expression of functional isoforms of mouse folypoly-gamma-glutamae synthetase: a basis for targeting folate antimetabolites.Cancer Res1999
9748272Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate.J Biol Chem1998
9223434The C-terminal domain of tissue inhibitor of metalloproteinases-2 is required for cell binding but not for antimetalloproteinase activity.Biochem Biophys Res Commun1997
7721888Upstream organization of and multiple transcripts from the human folylpoly-gamma-glutamate synthetase gene.J Biol Chem1995
8521387Structural organization of the human folypoly-gamma-glutamate synthetase gene: evidence for a single genomic locus.Cancer Res1995
7978795Matrix metalloproteinases and their inhibitors in tumor progression.Ann N Y Acad Sci1994
8004956Tissue inhibitors of metalloproteinases: role in tumor progression.Contrib Nephrol1994
7959781Assignment of a human melanoma associated gene MG50 (D2S448) to chromosome 2p25.3 by fluorescence in situ hybridization.Genomics1994
7923181Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line.Cancer Res1994
76833535-Aza-2'-deoxycytidine: cell differentiation and DNA methylation.Leukemia1993
8299947Mouse cDNAs encoding a trifunctional protein of de novo purine synthesis and a related single-domain glycinamide ribonucleotide synthetase.Gene1993
1732058Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases.Cancer Res1992
2415475Cellular differentiation.Int J Obes1985
62013215-Azacytidine, DNA methylation, and differentiation.Curr Top Microbiol Immunol1984
6189159Inhibition of DNA methylation by 5-azacytidine.Recent Results Cancer Res1983
6198436DNA modification, differentiation, and transformation.J Exp Zool1983
6175964Cell cycle-specific reactivation of an inactive X-chromosome locus by 5-azadeoxycytidine.Proc Natl Acad Sci U S A1982
6187927Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNA.J Mol Biol1982
6177706Changes in phenotypic expression in embryonic and adult cells treated with 5-azacytidine.J Cell Physiol1982
6169003Hemimethylated duplex DNAs prepared from 5-azacytidine-treated cells.Nucleic Acids Res1981
6156004Cellular differentiation, cytidine analogs and DNA methylation.Cell1980
6161112Histochemical demonstration of myosin Ca2+-ATPase accumulation in primary cultures of skeletal and heart muscle cells.Histochem J1980
90553Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine.Cell1979
87352Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides.Dev Biol1978
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Collaborators

Mikhail G Dozmorov
Virginia Commonwealth University
Co-authored papers 2
Erica J Peterson
Massey Cancer Center, Virginia Commonwealth University
Co-authored papers 2
Mathew J Garnett
Wellcome Sanger Institute
Co-authored papers 1
Yael P Mosse
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 1
Ultan McDermott
Wellcome Sanger Institute
Co-authored papers 1
Cyril H Benes
Co-authored papers 1
Kateryna Krytska
University of Pennsylvania Perelman School of Medicine
Co-authored papers 1
Yotam Drier
Co-authored papers 1
Bradley E Bernstein
Broad Institute of MIT and Harvard
Co-authored papers 1
Oliver B??gler
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 1
Robert Deans
Synthego Corporation
Co-authored papers 1
Lecia V Sequist
Massachusetts General Hospital Cancer Center, Harvard Medical School
Co-authored papers 1
Release 1.2