Author details

Full Name

Chris Cotsapas

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37202401	Developing OCHROdb, a comprehensive quality checked database of open chromatin regions from sequencing data.	Sci Rep	2023
37337107	Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.	Nat Genet	2023
37327781	Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients.	Cell Rep Med	2023
35051933	Seasonal Variation and Risk of Febrile Seizures: A Danish Nationwide Cohort Study.	Neuroepidemiology	2022
35963264	Genetics of multiple sclerosis: lessons from polygenicity.	Lancet Neurology, The	2022
36515579	The missing link between genetic association and regulatory function.	Elife	2022
34099189	Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.	Biol Psychiatry	2022
33249752	Epilepsy risk in offspring of affected parents; a cohort study of the "maternal effect" in epilepsy.	Annals of Clinical and Translational Neurology	2021
34061775	Do monogenic inborn errors of immunity cause susceptibility to severe COVID-19?	Journal of Clinical Investigation	2021
33664438	Shared associations identify causal relationships between gene expression and immune cell phenotypes.	Commun Biol	2021
33822360	Birth characteristics and risk of febrile seizures.	Acta Neurologica Scandinavica	2021
30528754	Childhood seizures and risk of psychiatric disorders in adolescence and early adulthood: a Danish nationwide cohort study.		2019
29478610	Multiple sclerosis.	Handb Clin Neurol	2018
29930110	Analysis of shared heritability in common disorders of the brain.	Science	2018
29881546	Genome-wide association studies of multiple sclerosis.	Clinical and Translational Immunology	2018
30128152	Erratum: Genome-wide association studies of multiple sclerosis.	Clinical and Translational Immunology	2018
28218759	Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types.	Nat Genet	2017
28686857	Integrative Genetic and Epigenetic Analysis Uncovers Regulatory Mechanisms of Autoimmune Disease.	Am J Hum Genet	2017
29093268	Microbiota control immune regulation in humanized mice.	JCI Insight	2017
28087842	Novel determinants of mammalian primary microRNA processing revealed by systematic evaluation of hairpin-containing transcripts and human genetic variation.	Genome Research	2017
28285767	Large-Scale trans-eQTLs Affect Hundreds of Transcripts and Mediate Patterns of Transcriptional Co-regulation.	Am J Hum Genet	2017
26518356	Changes in T-cell subsets identify responders to FcR-nonbinding anti-CD3 mAb (teplizumab) in patients with type 1 diabetes.	Eur J Immunol	2016
27305007	Network Analysis of Genome-Wide Selective Constraint Reveals a Gene Network Active in Early Fetal Brain Intolerant of Mutation.	PLoS Genet	2016
27013732	Survey of variation in human transcription factors reveals prevalent DNA binding changes.	Science	2016
26880555	Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.	Elife	2016
27210268	Progress and challenges for treating Type 1 diabetes.	J Autoimmun	2016
26062845	Genetic variants associated with autoimmunity drive NFÎºB signaling and responses to inflammatory stimuli.	Sci Transl Med	2015
25934857	Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.	Neurology	2015
27066539	Genetic analysis for a shared biological basis between migraine and coronary artery disease.	Neurol Genet	2015
26343388	Class II HLA interactions modulate genetic risk for multiple sclerosis.	Nat Genet	2015
24598797	MHC associations with clinical and autoantibody manifestations in European SLE.	Genes Immun	2014
23031829	Immune-mediated disease genetics: the shared basis of pathogenesis.	Trends Immunol	2013
24076602	Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.	Nat Genet	2013
23752797	Pleiotropy in complex traits: challenges and strategies.	Nat Rev Genet	2013
23921886	Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis.	Neurology	2013
23643386	Weight loss after gastric bypass is associated with a variant at 15q26.1.	Am J Hum Genet	2013
23084292	Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.	Am J Hum Genet	2012
22955828	Systematic localization of common disease-associated variation in regulatory DNA.	Science	2012
23041452	Human genetics offers an emerging picture of common pathways and mechanisms in autoimmunity.	Curr Opin Immunol	2012
21832118	Heritability of the weight loss response to gastric bypass surgery.	J Clin Endocrinol Metab	2011
21249183	Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.	PLoS Genet	2011
21852963	Pervasive sharing of genetic effects in autoimmune disease.	PLoS Genet	2011
20439770	Fine mapping in 94 inbred mouse strains using a high-density haplotype resource.	Genetics	2010
20703447	Expression analysis of loci associated with type 2 diabetes in human tissues.	Diabetologia	2010
19424753	Intra- and inter-individual genetic differences in gene expression.	Mamm Genome	2009
19553259	Common body mass index-associated variants confer risk of extreme obesity.	Hum Mol Genet	2009
18781858	Identifying genetic components of drug response in mice.	Pharmacogenomics	2008
19043577	Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines.	PLoS Genet	2008
19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Nat Genet	2008
17764721	Gene expression profiles in zebrafish (Danio rerio) liver cells exposed to a mixture of pharmaceuticals at environmentally relevant concentrations.	Chemosphere	2007