|
| 37751743 | Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy. | Cell Chem Biol | 2024 |
| 36928661 | Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers. | Nucleic Acids Res | 2023 |
| 37961351 | ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers. | bioRxiv | 2023 |
| 38066556 | DNA methylation modulated genetic variant effect on gene transcriptional regulation. | Genome Biol | 2023 |
| 37549269 | SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1. | Proc Natl Acad Sci U S A | 2023 |
| 37478850 | Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer. | Cancer Cell | 2023 |
| 37478845 | A lncRNA from the FTO locus acts as a suppressor of the m<sup>6</sup>A writer complex and p53 tumor suppression signaling. | Mol Cell | 2023 |
| 37694973 | Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer. | Cancer Discov | 2023 |
| 37692852 | Genome-wide studies in prostate cancer poised liquid biopsy as a molecular discovery tool. | Front Oncol | 2023 |
| 37402621 | MEDIPIPE: an automated and comprehensive pipeline for cfMeDIP-seq data quality control and analysis. | Bioinformatics | 2023 |
| 37169182 | ALKBH5 Drives Immune Suppression Via Targeting AXIN2 to Promote Colorectal Cancer and Is a Target for Boosting Immunotherapy. | Gastroenterology | 2023 |
| 36997534 | MYC reshapes CTCF-mediated chromatin architecture in prostate cancer. | Nat Commun | 2023 |
| 36877164 | LSD1 Inhibition Disrupts Super-Enhancer-Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer. | Cancer Res | 2023 |
| 36610996 | A polygenic two-hit hypothesis for prostate cancer. | J Natl Cancer Inst | 2023 |
| 34511601 | TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization. | Cell Death Differ | 2022 |
| 36309516 | The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors. | Nat Commun | 2022 |
| 36129942 | CYCLIN K down-regulation induces androgen receptor gene intronic polyadenylation, variant expression and PARP inhibitor vulnerability in castration-resistant prostate cancer. | Proc Natl Acad Sci U S A | 2022 |
| 36251389 | The 5-Hydroxymethylcytosine Landscape of Prostate Cancer. | Cancer Res | 2022 |
| 35154288 | The Basis and Promise of Programmable RNA Editing and Modification. | Front Genet | 2022 |
| 35181738 | Neonatal LTβR signaling is required for the accumulation of eosinophils in the inflamed adult mesenteric lymph node. | Mucosal Immunol | 2022 |
| 34975152 | RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition. | Oncogene | 2022 |
| 35121110 | Exploiting the tumor-suppressive activity of the androgen receptor by CDK4/6 inhibition in castration-resistant prostate cancer. | Mol Ther | 2022 |
| 34968454 | N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer. | Gastroenterology | 2022 |
| 32946061 | Pioneer of prostate cancer: past, present and the future of FOXA1. | Protein Cell | 2021 |
| 33851458 | Hepatic Fibroblast Growth Factor 21 Is Involved in Mediating Functions of Liraglutide in Mice With Dietary Challenge. | Hepatology | 2021 |
| 33741908 | CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer. | Nat Commun | 2021 |
| 33542074 | Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies. | Clin Cancer Res | 2021 |
| 33822841 | Uncovering the dosage-dependent roles of Arid1a in gastric tumorigenesis for combinatorial drug therapy. | J Exp Med | 2021 |
| 33899001 | EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. | Nat Cancer | 2021 |
| 34911936 | Androgen receptor and MYC equilibration centralizes on developmental super-enhancer. | Nat Commun | 2021 |
| 34615997 | ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice. | Oncogene | 2021 |
| 34588438 | SPOP mutation induces DNA methylation via stabilizing GLP/G9a. | Nat Commun | 2021 |
| 34489572 | An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer. | Nat Cell Biol | 2021 |
| 34716314 | Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse. | Nat Commun | 2021 |
| 34621019 | CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer. | Oncogene | 2021 |
| 34075878 | HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness. | Elife | 2021 |
| 34168051 | Combined EZH2 Inhibition and IKAROS Degradation Leads to Enhanced Antitumor Activity in Diffuse Large B-cell Lymphoma. | Clin Cancer Res | 2021 |
| 33217448 | RNA N<sup>6</sup>-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m<sup>6</sup>A-GLUT1-mTORC1 Axis and Is a Therapeutic Target. | Gastroenterology | 2021 |
| 33420488 | Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression. | Nat Cell Biol | 2021 |
| 33270841 | CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy. | Blood | 2021 |
| 33417860 | Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy. | Cell | 2021 |
| 32203133 | Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice. | Cell Res | 2020 |
| 31662330 | MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer. | Clin Cancer Res | 2020 |
| 31974375 | Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer. | Nat Commun | 2020 |
| 32714761 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. | Adv Sci (Weinh) | 2020 |
| 32938917 | Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes. | Nat Commun | 2020 |
| 32868907 | Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer. | Nat Genet | 2020 |
| 30655535 | ONECUT2 is a driver of neuroendocrine prostate cancer. | Nat Commun | 2019 |
| 31844668 | Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer. | Sci Adv | 2019 |
| 31862865 | Early-life programming of mesenteric lymph node stromal cell identity by the lymphotoxin pathway regulates adult mucosal immunity. | Sci Immunol | 2019 |