Author details

Full Name

Toomas Haller

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36966134	Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond.	Nat Commun	2023
37034709	Untargeted metabolomics profiling in pediatric patients and adult populations indicates a connection between lipid imbalance and epilepsy.	medRxiv	2023
36966315	Common clinical blood and urine biomarkers for ischemic stroke: an Estonian Electronic Health Records database study.	Eur J Med Res	2023
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
35697829	Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.	Commun Biol	2022
33946982	Advances in Genomic Discovery and Implications for Personalized Prevention and Medicine: Estonia as Example.	J Pers Med	2021
34543281	The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.	PLoS Med	2021
34101054	Association analysis of juvenile idiopathic arthritis genetic susceptibility factors in Estonian patients.	Clinical Rheumatology	2021
32242022	Ancestry deconvolution and partial polygenic score can improve susceptibility predictions in recently admixed individuals.	Nature Communications	2020
30420678	Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records.	Eur J Hum Genet	2019
31152163	A catalog of genetic loci associated with kidney function from analyses of a million individuals.	Nat Genet	2019
31125048	Search for Early Pancreatic Cancer Blood Biomarkers in Five European Prospective Population Biobanks Using Metabolomics.	Endocrinology	2019
30808845	Genome-Wide Association Scan of Serum Urea in European Populations Identifies Two Novel Loci.	Am J Nephrol	2019
30634901	Manhattan Harvester and Cropper: a system for GWAS peak detection.	BMC Bioinformatics	2019
29316447	Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies.	Alzheimers Dement	2018
30323304	Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations.	Sci Rep	2018
29808027	Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.	Nat Genet	2018
29536759	Genome-wide analysis of nuclear magnetic resonance metabolites revealed parent-of-origin effect on triglycerides in medium very low-density lipoprotein in PTPRD gene.	Biomarkers in Medicine	2018
27469612	Metabolites of milk intake: a metabolomic approach in UK twins with findings replicated in two European cohorts.	Eur J Nutr	2017
28832619	Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	PLoS Genet	2017
28448500	Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.	PLoS Genet	2017
28107396	MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies.	PLoS One	2017
27005778	Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.	Nat Commun	2016
27020472	Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.	Nat Commun	2016
24008273	RegScan: a GWAS tool for quick estimation of allele effects on continuous traits and their combinations.	Briefings in Bioinformatics	2015
26251408	Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes.	Diabetes Care	2015
26068415	Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.	Nat Commun	2015
25811787	Modulation of genetic associations with serum urate levels by body-mass-index in humans.	PLoS One	2015
25673413	Genetic studies of body mass index yield new insights for obesity biology.	Nature	2015
25673412	New genetic loci link adipose and insulin biology to body fat distribution.	Nature	2015
24518929	Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu.	Int J Epidemiol	2015
24586121	Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons.	PLoS Medicine	2014
25282103	Defining the role of common variation in the genomic and biological architecture of adult human height.	Nat Genet	2014
24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Am J Hum Genet	2013
23263486	Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.	Nat Genet	2013
22267201	Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.	Nat Genet	2012
21909110	Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.	Nat Genet	2011
21133125	A voxel-based Monte Carlo model of drug release from bulk eroding nanoparticles.	J Nanosci Nanotechnol	2010
18950999	Sleeping beauty mutase (sbm) is expressed and interacts with ygfd in Escherichia coli.	Microbiol Res	2009
11263873	The crotonase superfamily: divergently related enzymes that catalyze different reactions involving acyl coenzyme a thioesters.	Acc Chem Res	2001
10769117	Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli.	Biochemistry	2000
10769118	New reactions in the crotonase superfamily: structure of methylmalonyl CoA decarboxylase from Escherichia coli.	Biochemistry	2000