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Author Details

Edwin M Posadas
Cedars-Sinai Medical Center
1993
122
40
PMIDPaper TitleJournal TitlePublished Year
35908246HCC EV ECG score: An extracellular vesicle-based protein assay for detection of early-stage hepatocellular carcinoma.Hepatology2023
36959101Targeting Glutamine Metabolism in Prostate Cancer.Front Biosci (Elite Ed)2023
37172577Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment.Cell Metab2023
37268911A cisplatin conjugate with tumor cell specificity exhibits antitumor effects in renal cancer models.BMC Cancer2023
36711067Prostate cancer extracellular vesicle digital scoring assay - a rapid noninvasive approach for quantification of disease-relevant mRNAs.Nano Today2023
36045587Antagonizing CD105 and androgen receptor to target stromal-epithelial interactions for clinical benefit.Mol Ther2023
34896918Discovery and characterization of circulating tumor cell clusters in neuroendocrine tumor patients using nanosubstrate-embedded microchips.Biosens Bioelectron2022
35377775Variation in Communication of Competing Risks of Mortality in Prostate Cancer Treatment Consultations.J Urol2022
36251389The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.Cancer Res2022
35877083Intensification of Androgen Deprivation Therapy in High-Risk, Nonmetastatic Prostate Cancer: Lessons From STAMPEDE.JNCI Cancer Spectr2022
35175588First-line Immune Checkpoint Inhibitor Combinations in Metastatic Renal Cell Carcinoma: Where Are We Going, Where Have We Been?Drugs2022
35115556Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis.Nat Commun2022
35237181Circulating Fatty Objects and Their Preferential Presence in Pancreatic Cancer Patient Blood Samples.Front Physiol2022
33422353Quantitative and Qualitative Analysis of Blood-based Liquid Biopsies to Inform Clinical Decision-making in Prostate Cancer.Eur Urol2021
33683795Disparities in Cancer Care and the Asian American Population.Oncologist2021
33712498Correction: A Randomized Controlled Trial of a 6-Month Low-Carbohydrate Intervention on Disease Progression in Men with Recurrent Prostate Cancer: Carbohydrate and Prostate Study 2 (CAPS2).Clin Cancer Res2021
33818052Integrating PARP Inhibitors Into Advanced Prostate Cancer Therapeutics.Oncology (Williston Park)2021
33754187Niraparib with androgen receptor-axis-targeted therapy in patients with metastatic castration-resistant prostate cancer: safety and pharmacokinetic results from a phase 1b study (BEDIVERE).Cancer Chemother Pharmacol2021
33531653A comparative study of PCS and PAM50 prostate cancer classification schemes.Prostate Cancer Prostatic Dis2021
34959723A Humanized Monoclonal Antibody Targeting Extracellular Nicotinamide Phosphoribosyltransferase Prevents Aggressive Prostate Cancer Progression.Pharmaceuticals (Basel)2021
34552338Clinical Utility of Olaparib in the Treatment of Metastatic Castration-Resistant Prostate Cancer: A Review of Current Evidence and Patient Selection.Onco Targets Ther2021
34524771Plasma Glutamine as a Prognostic Biomarker in Localized Prostate Cancer: Comparison of Conventional Variables in Risk Stratification.Oncology (Williston Park)2021
34541033Loss of CDCP1 triggers FAK activation in detached prostate cancer cells.Am J Clin Exp Urol2021
34541032Scaffold attachment factor B1 regulates androgen degradation pathways in prostate cancer.Am J Clin Exp Urol2021
34212072Covalent Chemistry-Mediated Multimarker Purification of Circulating Tumor Cells Enables Noninvasive Detection of Molecular Signatures of Hepatocellular Carcinoma.Adv Mater Technol2021
32017145Detection of Circulating Tumor Cells and Their Implications as a Biomarker for Diagnosis, Prognostication, and Therapeutic Monitoring in Hepatocellular Carcinoma.Hepatology2021
33451978Randomized Phase II Trial of Sipuleucel-T with or without Radium-223 in Men with Bone-metastatic Castration-resistant Prostate Cancer.Clin Cancer Res2021
32235862Loss of testosterone impairs anti-tumor neutrophil function.Nat Commun2020
32057540Deep androgen receptor suppression in prostate cancer exploits sexually dimorphic renal expression for systemic glucocorticoid exposure.Ann Oncol2020
32108029A Randomized Controlled Trial of a 6-Month Low-Carbohydrate Intervention on Disease Progression in Men with Recurrent Prostate Cancer: Carbohydrate and Prostate Study 2 (CAPS2).Clin Cancer Res2020
32631766Combination Androgen Receptor Inhibition and Docetaxel in Metastatic Castration-sensitive Prostate Cancer: The Next Step in First-line Treatment?Clin Genitourin Cancer2020
32895384Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring.Nat Commun2020
32366670Pharmacokinetics, Safety, and Antitumor Effect of Apalutamide with Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer: Phase Ib Study.Clin Cancer Res2020
32366119Evaluating Changes in Immune Function and Bone Microenvironment During Radium-223 Treatment of Patients with Castration-Resistant Prostate Cancer.Cancer Biother Radiopharm2020
32508311COVID-19 and androgen-targeted therapy for prostate cancer patients.Endocr Relat Cancer2020
32238563Cancer epithelia-derived mitochondrial DNA is a targetable initiator of a paracrine signaling loop that confers taxane resistance.Proc Natl Acad Sci U S A2020
30669895Developments in the use of tyrosine kinase inhibitors in the treatment of renal cell carcinoma.Expert Rev Anticancer Ther2019
30190302An Open Label Phase Ib Dose Escalation Study of TRC105 (Anti-Endoglin Antibody) with Axitinib in Patients with Metastatic Renal Cell Carcinoma.Oncologist2019
31244925A Circulating Tumor Cell-RNA Assay for Assessment of Androgen Receptor Signaling Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer.Theranostics2019
31232668Brain Metastases in Renal Cell Carcinoma: Immunotherapy Responsiveness Is Multifactorial and Heterogeneous.J Clin Oncol2019
31392269Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells.Sci Adv2019
30892008Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer.ACS Appl Mater Interfaces2019
30733185Role of Biomarkers in Prediction of Response to Therapeutics in Metastatic Renal-Cell Carcinoma.Clin Genitourin Cancer2019
30906615Brain Complete Response to Cabozantinib prior to Radiation Therapy in Metastatic Renal Cell Carcinoma.Case Rep Urol2019
28892262Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection.Adv Healthc Mater2018
30154147Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential.Cancer Res2018
30047926Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming.J Clin Invest2018
30094958Circulating monocytes from prostate cancer patients promote invasion and motility of epithelial cells.Cancer Med2018
29978216Safety and Efficacy of BIND-014, a Docetaxel Nanoparticle Targeting Prostate-Specific Membrane Antigen for Patients With Metastatic Castration-Resistant Prostate Cancer: A Phase 2 Clinical Trial.JAMA Oncol2018
30108686Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma.J Extracell Vesicles2018
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Collaborators

Hsian-Rong Tseng
Jonsson Comprehensive Cancer Center, University of California los angeles
Co-authored papers 23
Stephen J Freedland
Cedars-Sinai Medical Center
Co-authored papers 15
Sungyong You
Cedars-Sinai Medical Center
Co-authored papers 15
Michael R Freeman
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 14
Jie-Fu Chen
Memorial Sloan Kettering Cancer Center
Co-authored papers 14
Dolores Di Vizio
Cedars-Sinai Medical Center
Co-authored papers 11
Yu Jen Jan
Cedars-Sinai Medical Center
Co-authored papers 8
Vatche G Agopian
David Geffen School of Medicine , University of California los angeles
Co-authored papers 8
Howard M Sandler
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 7
Minhyung Kim
Roswell Park Comprehensive Cancer Center
Co-authored papers 7
Beatrice S Knudsen
University of Utah
Co-authored papers 6
Matthew J Smalley
European Cancer Stem Cell Research Institute, Cardiff University
Co-authored papers 5
Seth M Steinberg
Center for Cancer Research, National Cancer Institute
Co-authored papers 5
Felix Y Feng
UCSF Medical Center-Mount Zion
Co-authored papers 5
Leigh Ellis
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 4
Evan Y Yu
University of Washington and Fred Hutchinson Cancer Research Center
Co-authored papers 4
Matthew B Rettig
David Geffen School of Medicine, University of California los angeles
Co-authored papers 4
Emmanuel S Antonarakis
The Sidney Kimmel Cancer Comprehensive Cancer Center at Johns Hopkins
Co-authored papers 3
Eric A Klein
Cleveland Clinic
Co-authored papers 3
Jiaoti Huang
Duke University School of Medicine
Co-authored papers 3
Phuoc T Tran
University of Maryland School of Medicine
Co-authored papers 3
Steven-Huy B Han
David Geffen School of Medicine , University of California los angeles
Co-authored papers 3
Paul C Boutros
University of California los angeles
Co-authored papers 3
Chia-Lun Lu
University of California
Co-authored papers 3
Kim N Chi
University of British Columbia
Co-authored papers 3
Ekihiro Seki
Co-authored papers 2
Toni K Choueiri
Dana-Farber Cancer Institute
Co-authored papers 2
Scott A Tomlins
Rogel Cancer Center, University of Michigan Medical School ann arbor
Co-authored papers 2
Daniel E Spratt
University Hospitals Seidman Cancer Center, Case Western Reserve University
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Release 1.2