Author details

Full Name

Matthias Heinig

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37496039	Darier's disease exhibits a unique cutaneous microbial dysbiosis associated with inflammation and body malodour.		2023
36217029	A proteome-scale map of the SARS-CoV-2-human contactome.	Nat Biotechnol	2023
37938585	Speos: an ensemble graph representation learning framework to predict core gene candidates for complex diseases.		2023
37620858	An arrhythmogenic metabolite in atrial fibrillation.		2023
36637201	DeepSom: a CNN-based approach to somatic variant calling in WGS samples without a matched normal.		2023
36879886	Machine learning reveals STAT motifs as predictors for GR-mediated gene repression.		2023
36633909	A20 and the noncanonical NF-ÎºB pathway are key regulators of neutrophil recruitment during fetal ontogeny.		2023
35064145	Tissue-specific multi-omics analysis of atrial fibrillation.	Nat Commun	2022
36106915	Probing cell identity hierarchies by fate titration and collision during direct reprogramming.	Mol Syst Biol	2022
36344995	Network reconstruction for trans acting genetic loci using multi-omics data and prior information.	Genome Med	2022
35926050	Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies.	Science	2022
34638627	Risk Prediction of Cardiovascular Events by Exploration of Molecular Data with Explainable Artificial Intelligence.	International Journal of Molecular Sciences	2021
34183069	A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.	Genome Biol	2021
33707431	Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population.	Nat Commun	2021
32540397	Inflammatory macrophage memory in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease.	Journal of Allergy and Clinical Immunology	2021
34785648	scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies.	Nat Commun	2021
34876023	Polygenic risk for coronary artery disease in the Scottish and English population.	BMC Cardiovascular Disorders	2021
32612756	Seq-ing answers: Current data integration approaches to uncover mechanisms of transcriptional regulation.	Computational and Structural Biotechnology Journal	2020
32149610	The single-cell eQTLGen consortium.	Elife	2020
31249591	Inferring Interaction Networks From Multi-Omics Data.	Front Genet	2019
31706703	Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet.	Molecular Cell	2019
30893847	Association of Human Promoter Variants with the Occurrence of Knee-Osteoarthritis in a Case Control Association Study.	International Journal of Molecular Sciences	2019
29217450	Cadm2 regulates body weight and energy homeostasis in mice.	Molecular Metabolism	2018
30608189	Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction.	J Am Heart Assoc	2018
30503647	Efficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway Model.	Cell Syst	2018
29922679	Using Gene Expression to Annotate Cardiovascular GWAS Loci.	Frontiers in Cardiovascular Medicine	2018
30009572	Unilateral temporal interictal epileptiform discharges correctly predict the epileptogenic zone in lesional temporal lobe epilepsy.	Epilepsia	2018
29901703	MetaMap: an atlas of metatranscriptomic reads in human disease-related RNA-seq data.	Gigascience	2018
28158196	Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function.	PLoS ONE	2017
28903782	Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.	Genome Biol	2017
28423325	Rapid Genome-wide Recruitment of RNA Polymerase II Drives Transcription, Splicing, and Translation Events during T Cell Responses.	Cell Rep	2017
28628102	Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.	Nature Neuroscience	2017
27933526	Epigenetics and Control of RNAs.	Methods Mol Biol	2017
27659466	52 Genetic Loci Influencing MyocardialÂ Mass.	J Am Coll Cardiol	2016
27224515	Comparison of Cox Model Methods in A Low-dimensional Setting with Few Events.		2016
27260304	Principles of microRNA Regulation Revealed Through Modeling microRNA Expression Quantitative Trait Loci.	Genetics	2016
26988706	A roadmap of constitutive NF-ÎºB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses.	Genome Med	2016
26485286	High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.	J Clin Invest	2015
25884684	histoneHMM: Differential analysis of histone modifications with broad genomic footprints.	BMC Bioinformatics	2015
25589632	Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.	Sci Transl Med	2015
25738463	Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense.		2015
25959826	Quantitative interaction proteomics of neurodegenerative disease proteins.	Cell Rep	2015
26439713	Alternative Splicing Signatures in RNA-seq Data: Percent Spliced in (PSI).	Curr Protoc Hum Genet	2015
26007203	Translational regulation shapes the molecular landscape of complex disease phenotypes.	Nat Commun	2015
26502875	Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response.	J Neuroinflammation	2015
26542096	Meta-analysis identifies seven susceptibility loci involved in the atopic march.	Nat Commun	2015
24960161	RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.	J Clin Invest	2014
24353269	Unbiased expression mapping identifies a link between the complement and cholinergic systems in the rat central nervous system.	J Immunol	2014
24793478	Natural variation of histone modification and its impact on gene expression in the rat genome.	Genome Res	2014
23708188	Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.	Nat Genet	2013