Author details

Full Name

Bo Zhai

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
32296038	Author Correction: Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome.	Nat Commun	2020
30783264	Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.	Nat Cell Biol	2019
30226369	Nicotinamide N-Methyltransferase Interacts with Enzymes of the Methionine Cycle and Regulates Methyl Donor Metabolism.	Biochemistry	2018
28760857	FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.	Cancer Res	2017
26884171	MEKK2 mediates an alternative Î²-catenin pathway that promotes bone formation.	Proc Natl Acad Sci U S A	2016
26669439	mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy.	Proc Natl Acad Sci U S A	2015
25307156	Refined phosphopeptide enrichment by phosphate additive and the analysis of human brain phosphoproteome.	Proteomics	2015
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome.	Cell	2015
26252148	Erratum: A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides.	Nat Biotechnol	2015
26076430	A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides.	Nat Biotechnol	2015
25242320	Transcription factor networks in Drosophila melanogaster.	Cell Rep	2014
25284370	Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos.	Dev Cell	2014
24344204	TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex.	Mol Cell Biol	2014
24990963	Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.	Genes Dev	2014
24670654	Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.	Nature	2014
25135978	MicroRNA-8 promotes robust motor axon targeting by coordinate regulation of cell adhesion molecules during synapse development.	Philosophical Transactions of the Royal Society B: Biological Sciences	2014
24567360	Trim32 reduces PI3K-Akt-FoxO signaling in muscle atrophy by promoting plakoglobin-PI3K dissociation.	J Cell Biol	2014
24782546	Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells.	Proc Natl Acad Sci U S A	2014
23275560	Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA export.	Nucleic Acids Res	2013
24161930	Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.	Nat Cell Biol	2013
23945236	Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts.	J Clin Invest	2013
23918955	The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2.	J Exp Med	2013
22708077	SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.	Cell Rep	2012
22433861	Apoptotic cells can deliver chemotherapeutics to engulfing macrophages and suppress inflammatory cytokine production.	Journal of Biological Chemistry	2012
22908310	Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy.	J Cell Biol	2012
22770219	Acetylation-dependent regulation of Skp2 function.	Cell	2012
23022481	FUS-SMN protein interactions link the motor neuron diseases ALS and SMA.	Cell Rep	2012
21854985	Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival.	Cell	2011
21368833	SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.	Nature	2011
21725298	A large-scale method to measure absolute protein phosphorylation stoichiometries.	Nat Methods	2011
22006925	Regulation of cellular levels of Sprouty2 protein by prolyl hydroxylase domain and von Hippel-Lindau proteins.	J Biol Chem	2011
21965325	MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice.	J Clin Invest	2011
22036573	A protein complex network of Drosophila melanogaster.	Cell	2011
21551504	Correct interpretation of comprehensive phosphorylation dynamics requires normalization by protein expression changes.	Mol Cell Proteomics	2011
21694707	Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome.	Nat Commun	2011
22017875	mTOR drives its own activation via SCF(Î²TrCP)-dependent degradation of the mTOR inhibitor DEPTOR.	Mol Cell	2011
20498300	Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila.	Genetics	2010
20708156	Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.	Cancer Cell	2010
20832730	Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.	Mol Cell	2010
20686112	Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).	Proc Natl Acad Sci U S A	2010
20551513	The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice.	J Clin Invest	2010
19240029	The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition.	J Biol Chem	2009
19364924	A conserved CCCH-type zinc finger protein regulates mRNA nuclear adenylation and export.	J Cell Biol	2009
19536134	TAK1 is an essential regulator of BMP signalling in cartilage.	EMBO J	2009
18327897	Phosphoproteome analysis of Drosophila melanogaster embryos.	J Proteome Res	2008
11485308	C3G, a guanine nucleotide exchange factor bound to adapter molecule c-Crk, has two alternative splicing forms.	Biochemical and Biophysical Research Communications	2001
10926934	c-Crk, a substrate of the insulin-like growth factor-1 receptor tyrosine kinase, functions as an early signal mediator in the adipocyte differentiation process.	Journal of Biological Chemistry	2000