Author details

Full Name

Hu Li

Affiliation

ORCID

Career Start Year

2009

Papers

105

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36798821	Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug.		2023
37657444	Single-nucleus multiomic mapping of mA methylomes and transcriptomes in native populations of cells with sn-m6A-CT.		2023
37495204	Factors associated with discordance in the assessment of fibrosis stage between transient elastography and liver biopsy in NAFLD patients.		2023
37267954	Senescent alveolar macrophages promote early-stage lung tumorigenesis.		2023
37033267	Metabolic syndrome-related prognostic index: Predicting biochemical recurrence and differentiating between cold and hot tumors in prostate cancer.		2023
36225650	Generation of chromosome 1p/19q co-deletion by CRISPR/Cas9-guided genomic editing.	Neuro-Oncology Advances	2022
35795637	A Novel Non-Invasive Approach Based on Serum Ceruloplasmin for Identifying Non-Alcoholic Steatohepatitis Patients in the Non-Diabetic Population.	Frontiers in Medicine	2022
35776115	SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates.	Nucleic Acids Res	2022
35646902	Nuclear GSK-3Î² and Oncogenic KRas Lead to the Retention of Pancreatic Ductal Progenitor Cells Phenotypically Similar to Those Seen in IPMN.	Front Cell Dev Biol	2022
35607608	Hyperferritinemia Correlates to Metabolic Dysregulation and Steatosis in Chinese Biopsy-Proven Nonalcoholic Fatty Liver Disease Patients.	Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy	2022
34331666	LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells.	Protein Cell	2022
36256477	Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers.	JCI Insight	2022
33823155	A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition.	J Biol Chem	2021
33602789	GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma.	Cancer Res	2021
33407151	Analysis for interaction between interleukin-35 genes polymorphisms and risk factors on susceptibility to coronary heart disease in the Chinese Han population.	BMC Cardiovascular Disorders	2021
33148676	Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses.	Clinical Cancer Research	2021
32753686	TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response.	Mol Psychiatry	2021
34938193	Ursodeoxycholic Acid Treatment Restores Gut Microbiota and Alleviates Liver Inflammation in Non-Alcoholic Steatohepatitic Mouse Model.	Frontiers in Pharmacology	2021
32365352	Rho/SMAD/mTOR triple inhibition enables long-term expansion of human neonatal tracheal aspirate-derived airway basal cell-like cells.	Pediatric Research	2021
34584087	Multi-species single-cell transcriptomic analysis of ocular compartment regulons.	Nature Communications	2021
34453888	Interaction of tau with HNRNPA2B1 and N<sup>6</sup>-methyladenosine RNA mediates the progression of tauopathy.	Mol Cell	2021
34316715	Characterization of a <i>RAD51C</i>-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance.	NAR Cancer	2021
33842927	Machine Learning and Systems Biology Approaches to Characterize Dosage-Based Gene Dependencies in Cancer Cells.		2021
32011920	Reprogramming of Pluripotency-Specific microRNA Signatures Is Not Essential to Generate Inducible Pluripotent Stem Cells.	Cellular Reprogramming	2020
33292312	Tandem Mass Tag-based quantitative proteomics analysis of metabolic associated fatty liver disease induced by high fat diet in mice.	Nutrition and Metabolism	2020
33203881	ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL.	Nat Commun	2020
33136097	BubR1ï»¿ï»¿ allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.	Journal of Clinical Investigation	2020
33113365	Defining Essential Enhancers for Pluripotent Stem Cells Using a Features-Oriented CRISPR-Cas9 Screen.	Cell Reports	2020
32917699	Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing.	Science advances	2020
32699019	Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibility.	Genome Research	2020
32557866	Association of genetic variants in lncRNA GAS5/miR-21/mTOR axis with risk and prognosis of coronary artery disease among a Chinese population.	Journal of Clinical Laboratory Analysis	2020
32444465	Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.	Cancer Discov	2020
34841254	FoxM1 insufficiency hyperactivates Ect2-RhoA-mDia1 signaling to drive cancer.	Nature Cancer	2020
31523007	Microbial Metabolism Modulates Antibiotic Susceptibility within the Murine Gut Microbiome.		2019
31114928	Regulostat Inferelator: a novel network biology platform to uncover molecular devices that predetermine cellular response phenotypes.	Nucleic Acids Research	2019
30878468	Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice.	Gastroenterology	2019
30643186	Author Correction: ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors.	Nature Cell Biology	2019
30460631	Characterization of iPSCs derived from low grade gliomas revealed early regional chromosomal amplifications during gliomagenesis.	J Neurooncol	2019
31875547	Dysregulation of RNA Splicing in Tauopathies.	Cell Reports	2019
31827434	Ketamine and Active Ketamine Metabolites Regulate STAT3 and the Type I Interferon Pathway in Human Microglia: Molecular Mechanisms Linked to the Antidepressant Effects of Ketamine.	Front Pharmacol	2019
31561002	Glucocorticoid resistance of allogeneic T cells alters the gene expression profile in the inflamed small intestine of mice suffering from acute graft-versus-host disease.	Journal of Steroid Biochemistry and Molecular Biology	2019
29273772	Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.	Nature Neuroscience	2018
30068389	RNA binding proteins co-localize with small tau inclusions in tauopathy.	Acta neuropathologica communications	2018
30017354	Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles.	Cell Metab	2018
29757681	Lung-Resident Mesenchymal Stromal Cells Reveal Transcriptional Dynamics of Lung Development in Preterm Infants.	American Journal of Respiratory and Critical Care Medicine	2018
29670118	Global H3.3 dynamic deposition defines its bimodal role in cell fate transition.	Nature Communications	2018
29608141	Senescent cells: a therapeutic target for cardiovascular disease.	Journal of Clinical Investigation	2018
29592948	<i>TCL1A</i>, a Novel Transcription Factor and a Coregulator of Nuclear Factor <i>Îº</i>B p65: Single Nucleotide Polymorphism and Estrogen Dependence.	J Pharmacol Exp Ther	2018
29497036	Reconstruction of complex single-cell trajectories using CellRouter.	Nat Commun	2018
29440725	Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids.	Scientific Reports	2018