Skip to Main Content

Author Details

Conor R Caffrey
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
1987
161
45
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36534051Microtubule-Stabilizing 1,2,4-Triazolo[1,5-<i>a</i>]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.J Med Chem2023
37851179Human schistosomiasis in Nigeria: present status, diagnosis, chemotherapy, and herbal medicines.Parasitol Res2023
37083395Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022.ACS Infect Dis2023
36945407Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5- <i>a</i> ]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.bioRxiv2023
37298760Seaweeds and Corals from the Brazilian Coast: Review on Biotechnological Potential and Environmental Aspects.Molecules2023
37066163Development of subunit selective substrates for <i>Trichomonas vaginalis</i> proteasome.bioRxiv2023
36736493Activity of N-phenylbenzamide analogs against the neglected disease pathogen, Schistosoma mansoni.Bioorg Med Chem Lett2023
35048211Brazilian green propolis reduces worm burden and hepatic granuloma formation in a Schistosoma mansoni experimental murine model.Parasitol Res2022
35749989Designing and development of phthalimides as potent anti-tubulin hybrid molecules against malaria.Eur J Med Chem2022
36558759A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using <i>Leishmania donovani</i>.Pathogens2022
36181831EF24, a schistosomicidal curcumin analog: Insights from its synthesis and phenotypic, biochemical and cytotoxic activities.Chem Biol Interact2022
35910167Discovery of pH-Selective Marine and Plant Natural Product Inhibitors of Cathepsin B Revealed by Screening at Acidic and Neutral pH Conditions.ACS Omega2022
36062044Prevalence and Associated Risk Factors of Urinary Schistosomiasis among Primary School Pupils in the Jidawa and Zobiya Communities of Jigawa State, Nigeria.Ann Glob Health2022
36385939Identification of Inhibitors of the <i>Schistosoma mansoni</i> VKR2 Kinase Domain.ACS Med Chem Lett2022
36343429From rational design to serendipity: Discovery of novel thiosemicarbazones as potent trypanocidal compounds.Eur J Med Chem2022
33175511Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors.ACS Infect Dis2021
33568098Correction to: Understanding the key processes of excellence as a prerequisite to establishing academic centres of excellence in Africa.BMC Med Educ2021
34461718Structure-Based Optimization of Quinazolines as Cruzain and <i>Tbr</i>CATL Inhibitors.J Med Chem2021
34536671Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation.Eur J Med Chem2021
34246720Should the enzyme name 'rhodesain' be discontinued?Mol Biochem Parasitol2021
34156862Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis.J Med Chem2021
34231306Antiparasitic Properties of Propolis Extracts and Their Compounds.Chem Biodivers2021
33434015A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules.ACS Infect Dis2021
33135408Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of <i>Schistosoma mansoni</i> In Vitro.ACS Infect Dis2021
33301315Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to <i>Schistosoma mansoni</i>: Structural and Mechanistic Insights into Chemotype Reactivity.ACS Infect Dis2021
32196500Identification of anisomycin, prodigiosin and obatoclax as compounds with broad-spectrum anti-parasitic activity.PLoS Negl Trop Dis2020
31846577Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-<i>b</i>]pyridazines for the Treatment of Human African Trypanosomiasis.J Med Chem2020
31670951Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics.J Med Chem2020
32054976Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity.Sci Rep2020
33349640A multi-dimensional, time-lapse, high content screening platform applied to schistosomiasis drug discovery.Commun Biol2020
32578329Uncovering Biological Application of Brazilian Green Propolis: A Phenotypic Screening against Schistosoma mansoni.Chem Biodivers2020
32973030A single-cell RNA-seq atlas of <i>Schistosoma mansoni</i> identifies a key regulator of blood feeding.Science2020
32633155Design, synthesis, and <i>in vitro</i> evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors.J Enzyme Inhib Med Chem2020
32709866Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery.Nat Commun2020
32617557Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone.J Antimicrob Chemother2020
32184954Structure-Bioactivity Relationships of Lapatinib Derived Analogs against <i>Schistosoma mansoni</i>.ACS Med Chem Lett2020
32175287Isoforms of Cathepsin B1 in Neurotropic Schistosomula of <i>Trichobilharzia regenti</i> Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog Binds Cystatin.Front Cell Infect Microbiol2020
30653492A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response.PLoS Negl Trop Dis2019
31640761Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery.Parasit Vectors2019
31469332Benzimidazole inhibitors of the major cysteine protease of <i>Trypanosoma brucei</i>.Future Med Chem2019
31355632The Proteasome as a Drug Target in the Metazoan Pathogen, <i>Schistosoma mansoni</i>.ACS Infect Dis2019
31284086Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'.Eur J Med Chem2019
3145150320S Proteasome as a Drug Target in Trichomonas vaginalis.Antimicrob Agents Chemother2019
31192168Bioactivity of Farnesyltransferase Inhibitors Against <i>Entamoeba histolytica</i> and <i>Schistosoma mansoni</i>.Front Cell Infect Microbiol2019
31362766Molecular characterization and functional analysis of the Schistosoma mekongi Ca<sup>2+</sup>-dependent cysteine protease (calpain).Parasit Vectors2019
31158236Development and optimization of a high-throughput screening method utilizing Ancylostoma ceylanicum egg hatching to identify novel anthelmintics.PLoS One2019
30735501Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents.PLoS Negl Trop Dis2019
30958153Quantifying the mechanics of locomotion of the schistosome pathogen with respect to changes in its physical environment.J R Soc Interface2019
27071187Algorithmic Mapping and Characterization of the Drug-Induced Phenotypic-Response Space of Parasites Causing Schistosomiasis.IEEE/ACM Trans Comput Biol Bioinform2018
29969537Brain-Penetrant Triazolopyrimidine and Phenylpyrimidine Microtubule Stabilizers as Potential Leads to Treat Human African Trypanosomiasis.ChemMedChem2018
  • 1 - 50 of 161

Recommended Authors

University of California San Diego
Career Start Year 2017
Number of shared co-authors 7
a Division of The Scripps Research Institute
Career Start Year 2012
Number of shared co-authors 8
Department of Pharmaceutical Chemistry , University of California san francisco
Career Start Year 2011
Number of shared co-authors 3
CSIR - National Chemical Laboratory
Career Start Year 2008
Number of shared co-authors 9
European Bioinformatics Institute
Career Start Year 2007
Number of shared co-authors 2
Houston Methodist Hospital
Career Start Year 2007
Number of shared co-authors 1
Global Health Pharma Unit
Career Start Year 2005
Number of shared co-authors 6
University of Nebraska at Omaha
Career Start Year 2003
Number of shared co-authors 6
Stanford University School of Medicine
Career Start Year 2003
Number of shared co-authors 5
a division of The Scripps Research Institute La Jolla
Career Start Year 2003
Number of shared co-authors 1
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne
Career Start Year 2001
Number of shared co-authors 20
School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo
Career Start Year 2000
Number of shared co-authors 0
King Abdullah University of Science and Technology
Career Start Year 1997
Number of shared co-authors 18
Jikei University School of Medicine
Career Start Year 1996
Number of shared co-authors 0
National Institutes of Health Intramural Research Program
Career Start Year 1995
Number of shared co-authors 1
RWTH Aachen University
Career Start Year 1995
Number of shared co-authors 2
Universidad Nacional de San Martin
Career Start Year 1995
Number of shared co-authors 9
University of Toronto
Career Start Year 1991
Number of shared co-authors 7
Jozef Stefan Institute
Career Start Year 1990
Number of shared co-authors 1
Heidelberg University
Career Start Year 1989
Number of shared co-authors 1
New York University School of Medicine
Career Start Year 1985
Number of shared co-authors 1
University of Washington
Career Start Year 1984
Number of shared co-authors 10
Heidelberg University Biochemistry Center
Career Start Year 1982
Number of shared co-authors 1
University of Guelph
Career Start Year 1981
Number of shared co-authors 17
University of Hull
Career Start Year 1980
Number of shared co-authors 0
University of Pennsylvania
Career Start Year 1979
Number of shared co-authors 21
Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro
Career Start Year 1978
Number of shared co-authors 6
The Broad Institute
Career Start Year 1977
Number of shared co-authors 9
Seattle Children's Research Institute, University of Washington
Career Start Year 1977
Number of shared co-authors 3
Nursing and Health SciencesMonash UniversityClaytonVictoriaAustralia.
Career Start Year 1975
Number of shared co-authors 0

Collaborators

Sandler Center for Drug Discovery, University of California San Francisco
Co-authored papers 57
Qassim University
Co-authored papers 19
Czech University of Life Sciences
Co-authored papers 17
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 15
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 14
School of Public Health, University of California berkeley
Co-authored papers 5
University of California san francisco
Co-authored papers 5
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 4
Charles University
Co-authored papers 3
University of Sao Paulo (USP), School of Pharmaceutical Sciences of Ribeirao Preto
Co-authored papers 3
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
University of California san francisco
Co-authored papers 3
St. Jude Children's Research Hospital
Co-authored papers 3
The Joint Center for Structural Genomics, Stanford University
Co-authored papers 3
University of California san francisco
Co-authored papers 3
Charles University
Co-authored papers 3
University of California San Francisco
Co-authored papers 2
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 2
University of California at San Francisco
Co-authored papers 2
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 2
Harvard Medical School and Cardiovascular Division, Brigham and Women's Hospital
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 2
University of California
Co-authored papers 1
Hospital for Sick Children
Co-authored papers 1