Author details

Full Name

Nathan O Stitziel

Affiliation

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37291473	Low LDL Cholesterol Is Not an Independent Risk Factor for Hepatic Steatosis.		2023
35999139	Angiopoietin-like 3: An important protein in regulating lipoprotein levels.		2023
37673700	The emerging Janus face of SVEP1 in development and disease.		2023
37712257	ANGPTL3 Deficiency and Risk of Hepatic Steatosis.		2023
37034289	Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury.	JACC Basic Transl Sci	2023
37397085	Genetic Testing in Evaluating Risk ofÂ Anthracycline Cardiomyopathy: Are We There Yet?		2023
36747878	Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis.		2023
36932061	Author Correction: SVEP1 is an endogenous ligand for the orphan receptor PEAR1.		2023
36739943	Functional assays reveal the pathogenic mechanism of a de novo tropomyosin variant identified in patient with dilated cardiomyopathy.		2023
36792666	SVEP1 is an endogenous ligand for the orphan receptor PEAR1.		2023
35119614	Distribution of 54 polygenic risk scores for common diseases in long lived individuals and their offspring.	Geroscience	2022
36215801	Vascular smooth muscle- and myeloid cell-derived integrin Î±9Î²1 does not directly mediate the development of atherosclerosis in mice.	Atherosclerosis	2022
36055244	Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.	Am J Hum Genet	2022
28291654	Comments on Letter to the Editor entitled: "Role of electrophysiological evaluation for the best device choice to prevent sudden cardiac death in patients with Myotonic Dystrophy Type1 and Emery Dreifuss Muscular Dystrophy".	Trends in Cardiovascular Medicine	2021
33798444	Association of structural variation with cardiometabolic traits in Finns.	Am J Hum Genet	2021
34099068	Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences.	Hum Genomics	2021
33762433	SVEP1 is a human coronary artery disease locus that promotes atherosclerosis.	Science Translational Medicine	2021
32908252	Author Correction: High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy.	Nat Metab	2020
32423639	Emerging Targets for Cardiovascular Disease Prevention in Diabetes.	Trends in Molecular Medicine	2020
32128508	High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy.	Nat Metab	2020
32470373	Non-parametric Polygenic Risk Prediction via Partitioned GWAS Summary Statistics.	Am J Hum Genet	2020
30988515	Roadmap for a precision-medicine initiative in the Nordic region.	Nat Genet	2019
31645127	Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease.	Arterioscler Thromb Vasc Biol	2019
31686056	Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power.	Nature	2019
30355262	Capitalizing on Insights from Human Genetics to Identify Novel Therapeutic Targets for Coronary Artery Disease.	Annual Review of Medicine	2019
31211696	Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress.	JCI Insight	2019
31256696	Coronary Artery Disease Risk and Lipidomic Profiles Are Similar in Hyperlipidemias With Family History and Population-Ascertained Hyperlipidemias.	J Am Heart Assoc	2019
31367044	Exome sequencing of Finnish isolates enhances rare-variant association power.	Nature	2019
29656146	Genetics of the extracellular matrix in aortic aneurysmal diseases.	Matrix Biology	2018
28982690	Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.	Circulation	2018
30071997	Clinical Genetic Testing for FamilialÂ Hypercholesterolemia: JACC Scientific Expert Panel.	J Am Coll Cardiol	2018
30131872	An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery.	NPJ Genom Med	2018
29386597	New Sequencing technologies help revealing unexpected mutations in Autosomal Dominant Hypercholesterolemia.	Scientific Reports	2018
28209224	Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated WithÂ Coronary ArteryÂ Disease.	J Am Coll Cardiol	2017
28385496	ANGPTL3 Deficiency and Protection Against Coronary Artery Disease.	J Am Coll Cardiol	2017
28456354	Genetic association studies in cardiovascular diseases: Do we have enough power?	Trends in Cardiovascular Medicine	2017
29025568	Reply: Loss-of-Function Mutations to EstimateÂ Pharmacological ANGPTL3 Inhibition.	Journal of the American College of Cardiology	2017
29083408	Exome-wide association study of plasma lipids in >300,000 individuals.	Nat Genet	2017
27452966	Diagnosis and management of adult hereditary cardio-neuromuscular disorders: A model for the multidisciplinary care of complex genetic disorders.	Trends in Cardiovascular Medicine	2017
27940953	Genetic invalidation of Lp-PLA<sub>2</sub> as a therapeutic target: Large-scale study of five functional Lp-PLA<sub>2</sub>-lowering alleles.	Eur J Prev Cardiol	2017
28267856	Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease.	JAMA	2017
28059951	Human genetic insights into lipoproteins and risk of cardiometabolic disease.	Current Opinion in Lipidology	2017
27686272	Leveraging human genetics to guide drug target discovery.	Trends in Cardiovascular Medicine	2017
28223407	Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting.	Circulation	2017
28112900	Variants in ANGPTL4 and the Risk of Coronary Artery Disease.	New England Journal of Medicine	2016
26934567	Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.	N Engl J Med	2016
27432961	Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans.	Proc Natl Acad Sci U S A	2016
27013693	Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits.	Circ Cardiovasc Genet	2016
26965621	Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.	Science	2016
27618448	Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.	Nat Genet	2016