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Author Details

Fang Cai
Department of Pharmacy, Fuzhou Second Hospital
2003
138
35
PMIDPaper TitleJournal TitlePublished Year
36382774Cytotoxic lanostane-type triterpenes from the fruiting bodies of <i>Ganoderma lucidum</i>.Nat Prod Res2023
37089693Intermittent hypoxia-induced enhancement of sociability and working memory associates with CNTNAP2 upregulation.Front Mol Neurosci2023
37171286USP25 contributes to defective neurogenesis and cognitive impairments.FASEB J2023
37271769CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors.Signal Transduct Target Ther2023
36995762Occurrence of rust disease Caused by Gymnosporangium pleoporum on Cotoneaster acutifolius in China.Plant Dis2023
36938736Regulation of USP25 by SP1 Associates with Amyloidogenesis.J Alzheimers Dis2023
36929625Prognostic value of severe acute respiratory syndrome coronavirus-2 viral load and antibodies in patients hospitalized with COVID-19.Clin Transl Sci2023
36755366A mechanistic PK/PD model to enable dose selection of the potent anti-tryptase antibody (MTPS9579A) in patients with moderate-to-severe asthma.Clin Transl Sci2023
36658382CNTNAP2 Protein Is Degraded by the Ubiquitin-Proteasome System and the Macroautophagy-Lysosome Pathway.Mol Neurobiol2023
36629784Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.FASEB J2023
34581002Dose-dependent inactivation of airway tryptase with a novel dissociating anti-tryptase antibody (MTPS9579A) in healthy participants: A randomized trial.Clin Transl Sci2022
35475258Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA).EClinicalMedicine2022
35769705Adenosine Downregulates the Activities of Glutamatergic Neurons in the Paraventricular Hypothalamic Nucleus Required for Sleep.Front Neurosci2022
35857704Integrated systems modeling of severe asthma: Exploration of IL-33/ST2 antagonism.CPT Pharmacometrics Syst Pharmacol2022
36327219Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative.PLoS Genet2022
35157370Phase I and scintigraphy studies to evaluate safety, tolerability, pharmacokinetics, and lung deposition of inhaled GDC-0214 in healthy volunteers.Clin Transl Sci2022
35229730USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation.J Clin Invest2022
34612846Prognostic and Predictive Biomarkers in Patients With Coronavirus Disease 2019 Treated With Tocilizumab in a Randomized Controlled Trial.Crit Care Med2022
32950103miR-204-3p/Nox4 Mediates Memory Deficits in a Mouse Model of Alzheimer's Disease.Mol Ther2021
33744327Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: A randomized, controlled, proof-of-activity trial.J Allergy Clin Immunol2021
35024375Safety and Efficacy of Tocilizumab 4 or 8 mg/kg in Hospitalized Patients With Moderate to Severe Coronavirus Disease 2019 Pneumonia: A Randomized Clinical Trial.Open Forum Infect Dis2021
34485198Case Report: <i>ISPD</i> Gene Mutation Leads to Dystroglycanopathies: Genotypic Phenotype Analysis and Treatment Exploration.Front Pediatr2021
29915376A presenilin-1 mutation causes Alzheimer disease without affecting Notch signaling.Mol Psychiatry2020
31885220A novel de novo nonsense mutation in ZC4H2 causes Wieacker-Wolff Syndrome.Mol Genet Genomic Med2020
32102983Identification of Alzheimer's disease-associated rare coding variants in the ECE2 gene.JCI Insight2020
32036361Ximenynic Acid Regulation of n-3 PUFA Content in Liver and Brain.Lifestyle Genom2020
32909660A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER).Clin Exp Allergy2020
30626751BACE2, a conditional β-secretase, contributes to Alzheimer's disease pathogenesis.JCI Insight2019
31174614Upregulation of MIF as a defense mechanism and a biomarker of Alzheimer's disease.Alzheimers Res Ther2019
31036051Regulation of global gene expression in brain by TMP21.Mol Brain2019
30940770Change in type-2 biomarkers and related cytokines with prednisolone in uncontrolled severe oral corticosteroid dependent asthmatics: an interventional open-label study.Thorax2019
30579835Reduced SNAP25 Protein Fragmentation Contributes to SNARE Complex Dysregulation in Schizophrenia Postmortem Brain.Neuroscience2019
28799137Ethanol Alters APP Processing and Aggravates Alzheimer-Associated Phenotypes.Mol Neurobiol2018
28233271A Novel Alzheimer-Associated SNP in Tmp21 Increases Amyloidogenesis.Mol Neurobiol2018
29219946C1206, a novel curcumin derivative, potently inhibits Hsp90 and human chronic myeloid leukemia cells in vitro.Acta Pharmacol Sin2018
28776265Traumatic Brain Injury Alters the Metabolism and Facilitates Alzheimer's Disease in a Murine Model.Mol Neurobiol2018
27825650Development of a multi-matrix LC-MS/MS method for urea quantitation and its application in human respiratory disease studies.J Pharm Biomed Anal2017
28119813C0818, a novel curcumin derivative, interacts with Hsp90 and inhibits Hsp90 ATPase activity.Acta Pharm Sin B2017
29755652Correlation of MDR1 gene polymorphism with propofol combined with remifentanil anesthesia in pediatric tonsillectomy.Oncotarget2017
29034234Interleukin-13 in Asthma and Other Eosinophilic Disorders.Front Med (Lausanne)2017
28626014BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.J Neurosci2017
28883638Mild traumatic brain injury induces memory deficits with alteration of gene expression profile.Sci Rep2017
28569067Comparative Proteomic Analysis of Posterior Silk Glands of Wild and Domesticated Silkworms Reveals Functional Evolution during Domestication.J Proteome Res2017
28892059A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.Nat Genet2017
25421211Location- and Subunit-Specific NMDA Receptors Determine the Developmental Sevoflurane Neurotoxicity Through ERK1/2 Signaling.Mol Neurobiol2016
26621121Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis.Neuroscience2016
27840952Effect of ximenynic acid on cell cycle arrest and apoptosis and COX-1 in HepG2 cells.Mol Med Rep2016
26993628A randomized trial of the efficacy and safety of quilizumab in adults with inadequately controlled allergic asthma.Respir Res2016
27097852Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses.Nat Commun2016
26936520Regulation of global gene expression and cell proliferation by APP.Sci Rep2016
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Collaborators

University of Toronto, 1 Kings College Circle
Co-authored papers 12
BC Cancer Research Institute
Co-authored papers 2
Genentech Inc.
Co-authored papers 2
Co-authored papers 1
Uppsala University
Co-authored papers 1
University of California los angeles
Co-authored papers 1
David Geffen School of Medicine, University of California-Los Angeles
Co-authored papers 1
Co-authored papers 1
McGill University
Co-authored papers 1
King Fahad Medical City and King Abdulaziz City for Science and Technology
Co-authored papers 1
Chulalongkorn University
Co-authored papers 1
University of Calgary
Co-authored papers 1
Keio University School of Medicine
Co-authored papers 1
23andMe Inc.
Co-authored papers 1
Institute of Molecular and Clinical Ophthalmology Basel (IOB)
Co-authored papers 1
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Icahn School of Medicine at Mount Sinai.
Co-authored papers 1
Instituto de Investigacion Sanitaria de Santiago
Co-authored papers 1
David Geffen School of Medicine, University of California-Los Angeles
Co-authored papers 1
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
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Institute of Molecular and Clinical Ophthalmology Basel (IOB)
Co-authored papers 1
Chulalongkorn University
Co-authored papers 1
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
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MNM Bioscience Inc.
Co-authored papers 1
Uppsala University
Co-authored papers 1
The Rockefeller University
Co-authored papers 1
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King Fahad Medical City and King Abdulaziz City for Science and Technology
Co-authored papers 1