Author details

Full Name

Christopher B Burge

Affiliation

ORCID

Career Start Year

1991

Papers

134

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37577470	Regulatory features aid interpretation of 3'UTR Variants.		2023
36321651	RBP Image Database: A resource for the systematic characterization of the subcellular distribution properties of human RNA binding proteins.	Nucleic Acids Res	2023
37745552	Systematic identification of disease-causing promoter and untranslated region variants in 8,040 undiagnosed individuals with rare disease.	medRxiv	2023
38014225	Molecular and Cellular Context Influences SCN8A Variant Function.	bioRxiv	2023
37805921	Splicing quality control mediated by DHX15 and its G-patch activator SUGP1.		2023
35044812	Widespread occurrence of hybrid internal-terminal exons in human transcriptomes.	Science advances	2022
36333352	Sensory nerves enhance triple-negative breast cancer invasion and metastasis via the axon guidance molecule PlexinB3.	npj Breast Cancer	2022
35474001	Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes.	Nature	2022
33402748	Author Correction: A large-scale binding and functional map of human RNA-binding proteins.	Nature	2021
33852893	Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.	Mol Cell	2021
32728249	Expanded encyclopaedias of DNA elements in the human and mouse genomes.	Nature	2020
32807990	Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity.	Nature Structural and Molecular Biology	2020
31251911	Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription.	Cell	2019
31649056	Cotargeting among microRNAs in the brain.	Genome Research	2019
30561649	Transcriptome alterations in myotonic dystrophy skeletal muscle and heart.	Hum Mol Genet	2019
30867432	Widespread PERK-dependent repression of ER targets in response to ER stress.	Scientific Reports	2019
30755444	Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes.	Cancer Res	2019
30910979	Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells.	Proceedings of the National Academy of Sciences of the United States of America	2019
30902979	Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA.	Nat Commun	2019
29293084	Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow.	Elife	2018
29883606	Sequence, Structure, and Context Preferences of Human RNA Binding Proteins.	Mol Cell	2018
30148878	Numerous recursive sites contribute to accuracy of splicing in long introns in flies.	PLoS Genetics	2018
30485811	Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain.	Cell Rep	2018
29280736	The kinetics of pre-mRNA splicing in the genome and the influence of gene architecture.	eLife	2017
28735747	A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons.	Neuron	2017
27773581	Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System.	Neuron	2016
27068461	Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival.	Cell Rep	2016
27378374	Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.	Nat Commun	2016
26907613	Distal Alternative Last Exons Localize mRNAs to Neural Projections.	Molecular Cell	2016
27473169	Identification of new branch points and unconventional introns in Saccharomyces cerevisiae.	RNA	2016
27690314	Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection.	PLoS Genetics	2016
27720642	RNA Sequence Context Effects Measured InÂ Vitro Predict InÂ Vivo Protein Binding and Regulation.	Molecular Cell	2016
26694591	Meta-analysis of RNA-seq expression data across species, tissues and studies.		2015
25801031	Origins and impacts of new mammalian exons.	Cell Reports	2015
25883322	Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins.	Genome Research	2015
25617416	Quantitative visualization of alternative exon expression from RNA-seq data.	Bioinformatics	2015
26068750	RNA Bind-n-Seq: Measuring the Binding Affinity Landscape of RNA-Binding Proteins.	Methods in Enzymology	2015
26149273	Interactome analysis brings splicing into focus.		2015
24837674	RNA Bind-n-Seq: quantitative assessment of the sequence and structural binding specificity of RNA binding proteins.	Molecular Cell	2014
25380226	Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state.	Elife	2014
25483039	Genomic analysis of RNA localization.	RNA Biology	2014
24869935	Muscleblind-like 1 (Mbnl1) regulates pre-mRNA alternative splicing during terminal erythropoiesis.	Blood	2014
24639172	MicroRNA target finding by comparative genomics.	Methods in Molecular Biology	2014
24857664	Widespread inhibition of posttranscriptional splicing shapes the cellular transcriptome following heat shock.	Cell Rep	2014
24752171	Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development.	Nature Communications	2014
24931974	Methods for time series analysis of RNA-seq data with application to human Th17 cell differentiation.		2014
23290915	Widespread regulation of translation by elongation pausing in heat shock.	Mol Cell	2013
23766421	Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay.	Genome Research	2013
24072873	3' UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts.	Genome Res	2013
23792564	Promoter directionality is controlled by U1 snRNP and polyadenylation signals.	Nature	2013