Author details

Full Name

Serena J Silver

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
33446805	SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.	Sci Rep	2021
31439712	Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers.	Mol Cancer Ther	2019
30380416	TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer.	Cell Rep	2018
30247463	Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening.	J Vis Exp	2018
29195078	A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.	Cell	2017
28753431	Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.	Cell	2017
24584072	An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.	Nat Genet	2014
24440720	ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.	Cell Rep	2014
22863010	Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.	Cell	2012
21706014	A public genome-scale lentiviral expression library of human ORFs.	Nat Methods	2011
21633165	The JAK2/STAT3 signaling pathway is required for growth of CD44âºCD24â» stem cell-like breast cancer cells in human tumors.	J Clin Invest	2011
20601955	Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.	Nat Genet	2010
20126544	CK1epsilon is required for breast cancers dependent on beta-catenin activity.	PLoS One	2010
20064372	A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.	Cell	2009
19490892	Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.	Cell	2009
19573809	AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.	Cancer Cell	2009
19800574	Proteomic and genetic approaches identify Syk as an AML target.	Cancer Cell	2009
19188593	Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning.	Proc Natl Acad Sci U S A	2009
19847166	Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.	Nature	2009
18794900	CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.	Nature	2008
17989227	Functional screening identifies miR-315 as a potent activator of Wingless signaling.	Proceedings of the National Academy of Sciences of the United States of America	2007
16964256	Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays.	Nature Methods	2006
15734575	New vision from Eyes absent: transcription factors as enzymes.	Trends in Genetics	2005
15802522	Using Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absent.	Genetics	2005
15590745	Signaling circuitries in development: insights from the retinal determination gene network.	Development (Cambridge)	2005
15286999	New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function.	Genesis	2004
14628053	The transcription factor Eyes absent is a protein tyrosine phosphatase.	Nature	2003
12917324	Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network.	Molecular and Cellular Biology	2003