Author details

Full Name

Leonid Padyukov

Affiliation

ORCID

Career Start Year

1984

Papers

280

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37326842	Genome-wide investigation of persistence with methotrexate treatment in early rheumatoid arthritis.	Rheumatology (Oxford)	2024
36600175	Occupational inhalable agents constitute major risk factors for rheumatoid arthritis, particularly in the context of genetic predisposition and smoking.		2023
37679551	Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.	Nat Immunol	2023
37563310	Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.	Nat Immunol	2023
37344505	Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs.		2023
37400429	Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality.	Nat Commun	2023
36824606	Functional link between sarcoidosis-associated gene variants and quantitative levels of bronchoalveolar lavage fluid cell types.		2023
36580032	Identification of Novel Associations and Localization of Signals in Idiopathic Inflammatory Myopathies Using Genome-Wide Imputation.	Arthritis Rheumatol	2023
37250650	Sex differences in the genetics of sarcoidosis across European and African ancestry populations.		2023
37052755	Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study.		2023
36798124	Analysis of IGH allele content in a sample group of rheumatoid arthritis patients demonstrates unrevealed population heterogeneity.		2023
37301908	Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality.	Nat Commun	2023
37051216	Molecular signature of methotrexate response among rheumatoid arthritis patients.		2023
35088123	Genetics of rheumatoid arthritis.	Seminars in Immunopathology	2022
36289551	Response to Comment "Sex-specific exposures and sex-combined outcomes in two-sample Mendelian randomization may mislead the causal inference" on "Age at menarche, age at natural menopause, and risk of rheumatoid arthritis-a Mendelian randomization study".		2022
36333501	Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.	Nat Genet	2022
36327907	Five commercially-available antibodies react differentially with allelic forms of human HLA-DR beta chain.	Molecular Immunology	2022
35470158	Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset.	Ann Rheum Dis	2022
34175943	Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis.	Rheumatology	2022
34279065	Contribution of Rare Genetic Variation to Disease Susceptibility in a Large Scandinavian Myositis Cohort.	Arthritis Rheumatol	2022
34902228	Toward Individualized Prediction of Response to Methotrexate in Early Rheumatoid Arthritis: A Pharmacogenomics-Driven Machine Learning Approach.	Arthritis Care Res (Hoboken)	2022
34658170	Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations.	ACR Open Rheumatology	2022
34484204	Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients.	Frontiers in Immunology	2021
32064741	Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.	Addict Biol	2021
33851187	Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.	medRxiv	2021
33788398	Clinical characteristics of Vietnamese patients with idiopathic inflammatory myopathies and autoantibodies to aminoacyl-transfer RNA synthetases.	International Journal of Rheumatic Diseases	2021
33836822	Age at menarche, age at natural menopause, and risk of rheumatoid arthritis - a Mendelian randomization study.		2021
33514426	The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study.		2021
33881221	Reply.	Arthritis and Rheumatology	2021
33037003	Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing.	Ann Rheum Dis	2021
32896263	HLA-B*27 is significantly enriched in Nordic patients with psoriatic arthritis mutilans.	Clinical and Experimental Rheumatology	2021
33381897	HLA-B*08 Identified as the Most Prominently Associated Major Histocompatibility Complex Locus for Anti-Carbamylated Protein Antibody-Positive/Anti-Cyclic Citrullinated Peptide-Negative Rheumatoid Arthritis.	Arthritis Rheumatol	2021
32581359	FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease.	Nature	2020
31629628	Soluble urokinase plasminogen activator receptor (suPAR) levels predict damage accrual in patients with recent-onset systemic lupus erythematosus.	J Autoimmun	2020
32176395	The importance of differences; On environment and its interactions with genes and immunity in the causation of rheumatoid arthritis.	Journal of Internal Medicine	2020
32218440	Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction.	Nat Commun	2020
32994363	Cigarette smoking patterns preceding primary SjÃ¶gren's syndrome.	RMD Open	2020
31375628	Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.	Proc Natl Acad Sci U S A	2019
31585111	Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype.	Am J Hum Genet	2019
31672989	GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.	Nat Commun	2019
31819081	A Gene-Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis.	Scientific Reports	2019
30573655	Genome-wide meta-analysis reveals shared new <i>loci</i> in systemic seropositive rheumatic diseases.	Ann Rheum Dis	2019
30371850	Clinical phenotype, autoantibody profile and HLA-DR-type in Vietnamese patients with idiopathic inflammatory myopathies.	Rheumatology	2019
30647177	Osteopontin and Disease Activity in Patients with Recent-onset Systemic Lupus Erythematosus: Results from the SLICC Inception Cohort.	J Rheumatol	2019
31138531	Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups.	Ann Rheum Dis	2019
31474319	Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype.	Am J Hum Genet	2019
31407831	Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.	Genet Epidemiol	2019
30936065	Sequencing of the MHC region defines <i>HLA-DQA1</i> as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population.	Ann Rheum Dis	2019
29795407	Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.	Pharmacogenomics J	2018
29930110	Analysis of shared heritability in common disorders of the brain.	Science	2018