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Author Details

Bingruo Wu
Albert Einstein College of Medicine
1994
43
21
PMIDPaper TitleJournal TitlePublished Year
37172927Identification of TNFα-mediated inflammation as potential pathological marker and therapeutic target for calcification progress of congenital bicuspid aortic valve.Eur J Pharmacol2023
37897735A sandwiched ventricular explant assay to model mouse coronary angiogenesis ex vivo.STAR Protoc2023
37702066<i>Crk</i> and <i>Crkl</i> Are Required in the Endocardial Lineage for Heart Valve Development.J Am Heart Assoc2023
37023750Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis.Dev Cell2023
37385754β-Catenin regulates endocardial cushion growth by suppressing p21.Life Sci Alliance2023
35862119Cardiac Myosin Heavy Chain Reporter Mice to Study Heart Development and Disease.Circ Res2022
34239905NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease.Front Cardiovasc Med2021
34497373Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling.Nat Cell Biol2021
31591643Control of sinus venous valve and sinoatrial node development by endocardial NOTCH1.Cardiovasc Res2020
31893948NFκB (Nuclear Factor κ-Light-Chain Enhancer of Activated B Cells) Activity Regulates Cell-Type-Specific and Context-Specific Susceptibility to Calcification in the Aortic Valve.Arterioscler Thromb Vasc Biol2020
31120883Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development.PLoS Genet2019
32537569Intrauterine Programming of Diabetes Induced Cardiac Embryopathy.Diabetes Obes Int J2019
29330540Author Correction: REST regulates the cell cycle for cardiac development and regeneration.Nat Commun2018
30201295Myocardial β-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation.J Mol Cell Cardiol2018
30347193NOTCH maintains developmental cardiac gene network through WNT5A.J Mol Cell Cardiol2018
29743679Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.Nature2018
27956497Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.Nucleic Acids Res2017
29056552Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis.Dev Cell2017
29215012REST regulates the cell cycle for cardiac development and regeneration.Nat Commun2017
28662157Sex-dependent aortic valve pathology in patients with rheumatic heart disease.PLoS One2017
28924218Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.Nat Commun2017
28790014BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling.Dev Biol2017
26491108Notch-Tnf signalling is required for development and homeostasis of arterial valves.Eur Heart J2017
27959615Developmental Mechanisms of Aortic Valve Malformation and Disease.Annu Rev Physiol2017
27266388A series of robust genetic indicators for definitive identification of cardiomyocytes.J Mol Cell Cardiol2016
28172500Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.Cardiovasc Res2016
27177150Circumferential Strain Can Be Used to Detect Lipopolysaccharide-Induced Myocardial Dysfunction and Predict the Mortality of Severe Sepsis in Mice.PLoS One2016
25848038Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade.Proc Natl Acad Sci U S A2015
26344772Vertebrate Fidgetin Restrains Axonal Growth by Severing Labile Domains of Microtubules.Cell Rep2015
26793347The role of speckle tracking echocardiography in assessment of lipopolysaccharide-induced myocardial dysfunction in mice.J Thorac Dis2015
24947998DNA methylation is developmentally regulated for genes essential for cardiogenesis.J Am Heart Assoc2014
23560082Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development.PLoS One2013
23824573Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.Development2013
23602386Brg1 governs a positive feedback circuit in the hair follicle for tissue regeneration and repair.Dev Cell2013
23669445Nfatc1 directs the endocardial progenitor cells to make heart valve primordium.Trends Cardiovasc Med2013
23178125Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling.Cell2012
21089072Cell autonomous requirement of endocardial Smad4 during atrioventricular cushion development in mouse embryos.Dev Dyn2011
21597012Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation.Circ Res2011
20014345Inducible cardiomyocyte-specific gene disruption directed by the rat Tnnt2 promoter in the mouse.Genesis2010
19411759Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.J Clin Invest2009
15689382Characterization of Nfatc1 regulation identifies an enhancer required for gene expression that is specific to pro-valve endocardial cells in the developing heart.Development2005
11786533Regulation of the murine Nfatc1 gene by NFATc2.J Biol Chem2002
7514599STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H(+)-ATPase subunit Vph1p.J Biol Chem1994
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Collaborators

Bin Zhou
Albert Einstein College of Medicine
Co-authored papers 39
Deyou Zheng
Co-authored papers 8
Chen-Leng Cai
Co-authored papers 4
Richard N Kitsis
Co-authored papers 2
Bin Zhou
The Central Hospital of Shaoyang
Co-authored papers 2
Verdon Taylor
University of Basel
Co-authored papers 2
William T Pu
Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
John M Greally
Co-authored papers 2
Yong Hu
Boston Children's Hospital
Co-authored papers 1
Xiaoqiang Cai
Co-authored papers 1
Qing Ma
Boston Children's Hospital
Co-authored papers 1
Patrick H Campbell
Wyss Institute for Biologically Inspired Engineering, Harvard University
Co-authored papers 1
Kari Alitalo
Wihuri Research Institute
Co-authored papers 1
Tamilla Nechiporuk
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 1
Francis X McGowan
Children's Hospital of Philadelphia
Co-authored papers 1
Masako Suzuki
Co-authored papers 1
Katalin Susztak
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Sergei G Tevosian
University of Florida College of Veterinary Medicine
Co-authored papers 1
Michael Rauchman
Co-authored papers 1
Brian O'Rourke
Co-authored papers 1
Nikolaos G Frangogiannis
Co-authored papers 1
Paul Robson
Co-authored papers 1
Weijia Zhang
Co-authored papers 1
Sek Won Kong
Boston Children's Hospital, Seoul National University, Seoul National University Hospital
Co-authored papers 1
Kate G Ackerman
University of Rochester
Co-authored papers 1
Peter W Baas
Drexel University College of Medicine
Co-authored papers 1
Release 1.2