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Author Details

Ekihiro Seki
2001
152
67
PMIDPaper TitleJournal TitlePublished Year
38086446Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis.J Hepatol2024
36669703Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1.2023
37270060In Vivo and In Vitro Models to Study Liver Fibrosis: Mechanisms and Limitations.2023
37247068Experimental Workflow for Preclinical Studies of Human Antifibrotic Therapies.2023
36930869Hyaluronan in liver fibrosis: basic mechanisms, clinical implications, and therapeutic targets.2023
37172577Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment.Cell Metab2023
36681094FAP: Not Just a Biomarker but Druggable Target in Liver Fibrosis.2023
35091576Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease.Nat Commun2022
36193675Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.Elife2022
35855954Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B.Canadian Journal of Gastroenterology and Hepatology2022
36387238Breast cancer liver metastasis: Pathogenesis and clinical implications.Frontiers in Oncology2022
35662287Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4.Experimental and Molecular Medicine2022
34571025An Intestine-Derived HDL as a Novel Regulator of the Activity of Gut-Derived LPS: Ushering in a New Era of Research on the Gut-Liver Axis.Gastroenterology2022
35018737Hepatocyte TGF-β Signaling Inhibiting WAT Browning to Promote NAFLD and Obesity Is Associated With Let-7b-5p.Hepatology Communications2022
34722513TAK1: A Molecular Link Between Liver Inflammation, Fibrosis, Steatosis, and Carcinogenesis.Frontiers in Cell and Developmental Biology2021
34129825Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.Cancer Cell2021
33486695Inhibition of hyaluronan synthesis by 4-methylumbelliferone ameliorates non-alcoholic steatohepatitis in choline-deficient L-amino acid-defined diet-induced murine model.Archives of Pharmacal Research2021
34289365Modeling alcohol-associated liver disease in a human Liver-Chip.Cell Reports2021
33905375Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts.Journal of Clinical Investigation2021
33535096Global Spread of a Local Fire: Transmission of Endoplasmic Reticulum Stress via Connexin 43.2021
33930309Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.Cancer Cell2021
33443222Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.Proc Natl Acad Sci U S A2021
34349244Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans.Oncogene2021
34461065Crossing the Rubicon: Adipose Tissue Autophagy Breaks Out NAFLD.Cellular and Molecular Gastroenterology and Hepatology2021
32848877Neurotropin Inhibits Lipid Accumulation by Maintaining Mitochondrial Function in Hepatocytes via AMPK Activation.Frontiers in Physiology2020
32080887Reciprocal Regulation Between Forkhead Box M1/NF-κB and Methionine Adenosyltransferase 1A Drives Liver Cancer.Hepatology2020
32242330Hepatic Stellate Cell-Macrophage Crosstalk in Liver Fibrosis and Carcinogenesis.Seminars in Liver Disease2020
31669157Kupffer Cell TLR2/3 Signaling: A Pathway for EGCG Amelioration of Ethanol-Induced Hepatic Injury.Cellular and Molecular Gastroenterology and Hepatology2020
32640349The liver fibrosis niche: Novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix.Food and Chemical Toxicology2020
33134488Increase in Alcoholic Hepatitis as an Etiology for Liver Transplantation in the United States: A 2004-2018 Analysis.Transplantation Direct2020
31044438NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.Hepatology2019
30523154The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.J Biol Chem2019
30766955Intestinal Lipolysis Mitigates Nonalcoholic Fatty Liver Disease: New Roles for Carboxylesterase 2c in the Intestine.Hepatology Communications2019
31235522Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria.Journal of Biological Chemistry2019
31171625Glial cell line-derived neurotrophic factor (GDNF) mediates hepatic stellate cell activation via ALK5/Smad signalling.Gut2019
30809789Inflammation and Liver Cancer: Molecular Mechanisms and Therapeutic Targets.Seminars in Liver Disease2019
30741922MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment.Cell Death Dis2019
31189722Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.Science Translational Medicine2019
31214376Alcoholic liver disease: A current molecular and clinical perspective.2018
28875549The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice.International Journal of Cancer2018
30300140Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.Journal of Clinical Investigation2018
30097701MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis.Archives of Toxicology2018
29956205Chemokines and Chemokine Receptors in the Development of NAFLD.Advances in Experimental Medicine and Biology2018
30288469Nuclear Receptors: Opening Up New Avenues of Pediatric Fatty Liver Research.Hepatology Communications2018
30287485Integrative genomic analysis of mouse and human hepatocellular carcinoma.Proc Natl Acad Sci U S A2018
30046112New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.Nature2018
30182043Tumor Suppressor Down-Regulation Promotes Hepatocyte Proliferation: A New GANKster on the Block.Cellular and Molecular Gastroenterology and Hepatology2018
30083132Interventional Potential of Recombinant Feline Hepatocyte Growth Factor in a Mouse Model of Non-alcoholic Steatohepatitis.Frontiers in Endocrinology2018
29894692Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.Cancer Cell2018
29531945Astrocyte elevated gene-1 (AEG-1): a new potential therapeutic target for the treatment of nonalcoholic steatohepatitis (NASH).2018
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