Author details

Full Name

Shizhen Zhu

Affiliation

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36866271	Manifold epigenetics: A conceptual model that guides engineering strategies to improve whole-body regenerative health.		2023
37371475	SPIN-AI: A Deep Learning Model That Identifies Spatially Predictive Genes.		2023
37242535	Network Biology-Inspired Machine Learning Features Predict Cancer Gene Targets and Reveal Target Coordinating Mechanisms.		2023
37183825	Genetic predisposition to neuroblastoma results from a regulatory polymorphism that promotes the adrenergic cell state.	J Clin Invest	2023
36909587	Genetic Predisposition to Neuroblastoma Results from a Regulatory Polymorphism that Promotes the Adrenergic Cell State.	bioRxiv	2023
35832612	Gene utility recapitulates chromosomal aberrancies in advanced stage neuroblastoma.	Computational and Structural Biotechnology Journal	2022
35911770	A Knowledge-Based Discovery Approach Couples Artificial Neural Networks With Weight Engineering to Uncover Immune-Related Processes Underpinning Clinical Traits of Breast Cancer.	Frontiers in Immunology	2022
33779609	Zebrafish Model of Neuroblastoma Metastasis.	Journal of Visualized Experiments	2021
33658627	A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma.	Oncogene	2021
33602789	GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma.	Cancer Res	2021
34233924	Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma.	Cancer Res	2021
33867859	Ze-Qi-Tang Formula Induces Granulocytic Myeloid-Derived Suppressor Cell Apoptosis via STAT3/S100A9/Bcl-2/Caspase-3 Signaling to Prolong the Survival of Mice with Orthotopic Lung Cancer.	Mediators of Inflammation	2021
33800887	Zebrafish as a Neuroblastoma Model: Progress Made, Promise for the Future.	Cells	2021
31936016	Ablation Behavior of a Carbon Fabric Reinforced Phenolic Composite Modified by Surface-Decorated ZrB/SiC.	Materials	2020
29231124	Unraveling Neuroblastoma Pathogenesis with the Zebrafish.	Cell Cycle	2018
29284669	<i>MYC</i> Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification.	Cancer Discov	2018
28263972	The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma.	Oncogene	2017
28867147	LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis.	Cancer Cell	2017
28765560	Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks.	Scientific Reports	2017
28329685	Critical Role for GAB2 in Neuroblastoma Pathogenesis through the Promotion of SHP2/MYCN Cooperation.	Cell Rep	2017
27130733	Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain.	Elife	2016
28035989	Neuroblastoma, a Paradigm for Big Data Science in Pediatric Oncology.	International Journal of Molecular Sciences	2016
27165366	Neuroblastoma and Its Zebrafish Model.	Adv Exp Med Biol	2016
25867597	Mosaic zebrafish transgenesis for functional genomic analysis of candidate cooperative genes in tumor pathogenesis.	Journal of Visualized Experiments	2015
26560027	Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.	Nature	2015
28793742	The ZrOâ¿¿ Formation in ZrBâ¿¿/SiC Composite Irradiated by Laser.	Materials	2015
22144284	Using zebrafish for studying Rho GTPases signaling in vivo.	Methods in Molecular Biology	2012
22439933	Activated ALK collaborates with MYCN in neuroblastoma pathogenesis.	Cancer Cell	2012
21727187	Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia.	J Exp Med	2011
20858602	Oligodendrocyte progenitor cell numbers and migration are regulated by the zebrafish orthologs of the NF1 tumor suppressor gene.	Hum Mol Genet	2010
20493809	Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis.	Dev Cell	2010
17873909	RhoA prevents apoptosis during zebrafish embryogenesis through activation of Mek/Erk pathway.	Oncogene	2008
18682746	K-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesis.	PLoS ONE	2008
16019189	RhoA acts downstream of Wnt5 and Wnt11 to regulate convergence and extension movements by involving effectors Rho kinase and Diaphanous: use of zebrafish as an in vivo model for GTPase signaling.	Cellular Signalling	2006