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Author Details

Sam Michael
National Center for Advancing Translational Sciences, National Institutes of Health
2008
72
29
PMIDPaper TitleJournal TitlePublished Year
37506331High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.Annu Rev Pharmacol Toxicol2024
36550275Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration.Nat Methods2023
37380628A landscape of response to drug combinations in non-small cell lung cancer.Nat Commun2023
37140427CellMinerCDB: NCATS Is a Web-Based Portal Integrating Public Cancer Cell Line Databases for Pharmacogenomic Explorations.Cancer Res2023
34128205Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules.Methods Mol Biol2022
35653613Retro Drug Design: From Target Properties to Molecular Structures.J Chem Inf Model2022
35648838Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.ACS Infect Dis2022
36669818Corrigendum to "An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication" [Genomics Proteomics Bioinformatics19 (1) (2021) 108-122].Genomics Proteomics Bioinformatics2022
36049119Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement.ACS Chem Biol2022
35119255High-Throughput Cellular Thermal Shift Assay Using Acoustic Transfer of Protein Lysates.ACS Chem Biol2022
35086793A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry.SLAS Discov2022
35141848Correction to: Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules.Methods Mol Biol2022
35057621A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research.J Chem Inf Model2022
35169799A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.bioRxiv2022
32805036The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment.J Am Med Inform Assoc2021
33848478Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress.Cancer Cell2021
33822623Discovery and Optimization of 2<i>H</i>-1λ<sup>2</sup>-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer.J Med Chem2021
33708112Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.Front Pharmacol2021
33532807Mapping a Pandemic: SARS-CoV-2 Seropositivity in the United States.medRxiv2021
33610792An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication.Genomics Proteomics Bioinformatics2021
33689873Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection.Bioorg Med Chem Lett2021
34861164Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells.Stem Cell Reports2021
34642691A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry.bioRxiv2021
34813400Cross-Platform Bayesian Optimization System for Autonomous Biological Assay Development.SLAS Technol2021
33941937A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells.Nat Methods2021
34158410Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States.Sci Transl Med2021
34013260Retro Drug Design: From Target Properties to Molecular Structures.bioRxiv2021
33346633The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules.ACS Infect Dis2021
33333292Synergistic and Antagonistic Drug Combinations against SARS-CoV-2.Mol Ther2021
33397956Standardization of ELISA protocols for serosurveys of the SARS-CoV-2 pandemic using clinical and at-home blood sampling.Nat Commun2021
32511355The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators.bioRxiv2020
33501193A Perspective on Innovating the Chemistry Lab Bench.Front Robot AI2020
32059197A biofabricated vascularized skin model of atopic dermatitis for preclinical studies.Biofabrication2020
33330839Identifying SARS-CoV-2 Entry Inhibitors through Drug Repurposing Screens of SARS-S and MERS-S Pseudotyped Particles.ACS Pharmacol Transl Sci2020
33173863A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research.bioRxiv2020
33062953Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening.ACS Pharmacol Transl Sci2020
32637956Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro.bioRxiv2020
32803196Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening.bioRxiv2020
32793899Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells.bioRxiv2020
32676161A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue.Oncotarget2020
32839777Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles.bioRxiv2020
32839771Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.bioRxiv2020
32233736Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences.SLAS Discov2020
32511472Standardization of enzyme-linked immunosorbent assays for serosurveys of the SARS-CoV-2 pandemic using clinical and at-home blood sampling.medRxiv2020
32511420An OpenData portal to share COVID-19 drug repurposing data in real time.bioRxiv2020
30289729Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy.SLAS Technol2019
31748226Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening.Sci Transl Med2019
31012573Detecting Secretory Proteins by Acoustic Droplet Ejection in Multiplexed High-Throughput Applications.ACS Chem Biol2019
31007132Fully Three-Dimensional Bioprinted Skin Equivalent Constructs with Validated Morphology and Barrier Function.Tissue Eng Part C Methods2019
30848454High-Throughput Screening for Drug Combinations.Methods Mol Biol2019
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Collaborators

Anton Simeonov
Co-authored papers 34
Min Shen
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 17
Marc Ferrer
National Institutes of Health, National Center for Advancing Translational Sciences
Co-authored papers 14
Craig J Thomas
Center for Cancer Research, National Cancer Institute
Co-authored papers 14
Christopher P Austin
St. George's University Medical School
Co-authored papers 11
Rajarshi Guha
Vertex Pharmaceuticals
Co-authored papers 10
Ajit Jadhav
Co-authored papers 8
Xiaohu Zhang
National Center for Advancing Translational Sciences
Co-authored papers 6
Donald C Lo
National Center for Advancing Translational Sciences
Co-authored papers 6
Ty C Voss
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 6
Noel Southall
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 4
Michele Ceribelli
National Center for Advancing Translational Sciences
Co-authored papers 4
Gergely Zahoránszky-Kſhalmi
Co-authored papers 4
Matthew B Boxer
Co-authored papers 4
Zhuyin Li
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 3
Yves Pommier
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Lars Juhl Jensen
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 2
Jiang Qian
Co-authored papers 2
Raymond R Tice
National Institute of Environmental Health Sciences
Co-authored papers 2
Tudor I Oprea
Expert Systems Inc.
Co-authored papers 2
Louis M Staudt
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Jianbo Pan
Co-authored papers 2
Vance P Lemmon
Co-authored papers 1
Jon Clardy
Harvard Medical School, Blavatnik Institute
Co-authored papers 1
George Hripscak
Columbia University
Co-authored papers 1
David Eichmann
The University of Iowa
Co-authored papers 1
Michael G Kurilla
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 1
Xiaohan Tanner Zhang
Johns Hopkins University School of Medicine
Co-authored papers 1
Michelle Monje
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Release 1.2