Author details

Full Name

Brent W Zanke

Affiliation

University of Toronto

ORCID

Career Start Year

1987

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36539618	Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.	Nat Genet	2023
36782065	Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.	Nat Genet	2023
30510241	Discovery of common and rare genetic risk variants for colorectal cancer.	Nat Genet	2019
29917119	Novel Common Genetic Susceptibility Loci for Colorectal Cancer.	J Natl Cancer Inst	2019
27460538	Principal component of explained variance: An efficient and optimal data dimension reduction framework for association studies.	Stat Methods Med Res	2018
29880713	Reply to Vickers: Pharmacogenetics and progression to neovascular age-related macular degeneration-Evidence supporting practice change.	Proc Natl Acad Sci U S A	2018
30320589	CFH and ARMS2 Polymorphisms Interact with Zinc Supplements in Cognitive Impairment in the Women's Health Initiative Hormone Trial.	J Alzheimers Dis	2018
29727690	A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics.	Am J Hum Genet	2018
29681304	Re: Assel et al.: Genetic polymorphisms of CFH and ARMS2 do not predict response to antioxidants and zinc in patients with age-related macular degeneration (Ophthalmology. 2018;125:391-397).	Ophthalmology	2018
29311295	<i>CFH</i> and <i>ARMS2</i> genetic risk determines progression to neovascular age-related macular degeneration after antioxidant and zinc supplementation.	Proc Natl Acad Sci U S A	2018
29161273	Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data.	PLoS One	2017
26766742	CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk.	Br J Cancer	2016
27459707	Telomere structure and maintenance gene variants and risk of five cancer types.	Int J Cancer	2016
24913512	A single-institution analysis of the utility of pre-induction ejection fraction measurement in patients newly diagnosed with acute myeloid leukemia.	Leuk Lymphoma	2015
26398061	Re: Chew et al.: Genetic testing in persons with age-related macular degeneration and the use of AREDS supplements: to test or not to test? (Ophthalmology 2015;122:212-5).	Ophthalmology	2015
26398056	Reply: To PMID 25200399.	Ophthalmology	2015
26498495	Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci.	Nat Commun	2015
26368860	The effect of 5-fluorouracil/leucovorin chemotherapy on CpG methylation, or the confounding role of leukocyte heterogeneity: An illustration.	Genomics	2015
26210598	Re: Chew et al.: No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38 (Ophthalmology 2014;121:2173-80).	Ophthalmology	2015
26071399	Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer.	Carcinogenesis	2015
26151821	Genome-wide association study of colorectal cancer identifies six new susceptibility loci.	Nat Commun	2015
25716334	Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci.	Nat Commun	2015
25781442	Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants.	JAMA	2015
25200399	Treatment response to antioxidants and zinc based on CFH and ARMS2 genetic risk allele number in the Age-Related Eye Disease Study.	Ophthalmology	2015
23935004	Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia.	Gut	2014
25599564	Functional normalization of 450k methylation array data improves replication in large cancer studies.	Genome Biol	2014
25192705	No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk.	Cancer Epidemiol Biomarkers Prev	2014
24994789	Gene-environment interaction involving recently identified colorectal cancer susceptibility Loci.	Cancer Epidemiol Biomarkers Prev	2014
25105248	Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A.	Nat Commun	2014
24743840	Genome-wide diet-gene interaction analyses for risk of colorectal cancer.	PLoS Genet	2014
24793507	Author reply: To PMID 23972322.	Ophthalmology	2014
24612979	Investigation of choroidal neovascularization risk alleles in ocular histoplasmosis.	Ophthalmology	2014
24154973	Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.	Int J Cancer	2014
22490517	Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals.	Gut	2013
23983240	Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer.	Cancer Epidemiol Biomarkers Prev	2013
23972322	CFH and ARMS2 genetic polymorphisms predict response to antioxidants and zinc in patients with age-related macular degeneration.	Ophthalmology	2013
23266556	Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.	Gastroenterology	2013
23314698	Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray.	Epigenetics	2013
21761138	Meta-analysis of new genome-wide association studies of colorectal cancer risk.	Hum Genet	2012
23240038	MLH1 region polymorphisms show a significant association with CpG island shore methylation in a large cohort of healthy individuals.	PLoS One	2012
23300701	Genome-wide search for gene-gene interactions in colorectal cancer.	PLoS One	2012
22843499	Genome-wide meta-analysis of common variant differences between men and women.	Hum Mol Genet	2012
22367214	Characterization of gene-environment interactions for colorectal cancer susceptibility loci.	Cancer Res	2012
21357381	Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study.	Cancer Epidemiol Biomarkers Prev	2011
20130705	A genetic approach to stratification of risk for age-related macular degeneration.	Can J Ophthalmol	2010
20967208	Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.	PLoS One	2010
20437058	The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.	Hum Genet	2010
20526366	Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies.	PLoS One	2010
19455140	Association of apolipoprotein E polymorphisms and dietary factors in colorectal cancer.	Br J Cancer	2009
19463769	Increased plasma EPO and MIP-1 alpha are associated with recruitment of vascular progenitors but not CD34(+) cells in autologous peripheral blood stem cell grafts.	Exp Hematol	2009

1 - 50 of 88

Kouros Owzar

Duke University

Career Start Year 2005

Number of shared co-authors 18

Min Shen

National Center for Advancing Translational Sciences, National Institutes of Health

Career Start Year 2003

Number of shared co-authors 17

Michael Slifker

Fox Chase Cancer Center

Career Start Year 2002

Number of shared co-authors 0

Keyue Ding

Queen's University

Career Start Year 2002

Number of shared co-authors 5

Gregory D Jenkins

Mayo Clinic

Career Start Year 2001

Number of shared co-authors 10

Pingfu Fu

Case Western Reserve University

Career Start Year 2000

Number of shared co-authors 29

Chao Xing

University of Texas Southwestern Medical Center

Career Start Year 1999

Number of shared co-authors 12

Christopher J Howlett

Western University

Career Start Year 1999

Number of shared co-authors 6

Kerby Shedden

University of Michigan ann arbor

Career Start Year 1999

Number of shared co-authors 1

Fahd Al-Mulla

Dasman Diabetes Institute

Career Start Year 1998

Number of shared co-authors 5

Patricia Porter-Gill

Arkansas Children's Research Institute

Career Start Year 1998

Number of shared co-authors 8

Dongquan Chen

University of Alabama at Birmingham

Career Start Year 1997

Number of shared co-authors 5

Clifton L Dalgard

Uniformed Services University of the Health Sciences

Career Start Year 1997

Number of shared co-authors 4

Sudhir Varma

Center for Cancer Research, National Cancer Institute

Career Start Year 1994

Number of shared co-authors 3

Jenny Xiang

Caryl and Israel Englander Institute for Precision Medicine.

Career Start Year 1993

Number of shared co-authors 1

Borko Jovanovic

Robert H Lurie Comprehensive Cancer Center of Northwestern University

Career Start Year 1991

Number of shared co-authors 0

Andrea Hofmann

Institute of Human Genetics, University of Bonn and Department of Genomics

Career Start Year 1991

Number of shared co-authors 2

Francisco M De La Vega

Stanford University School of Medicine

Career Start Year 1991

Number of shared co-authors 4

Abdel G Elkahloun

National Human Genome Research Institute

Career Start Year 1990

Number of shared co-authors 1

Jong-Il Kim

Genomic Medicine Institute, Medical Research Center, Seoul National University

Career Start Year 1989

Number of shared co-authors 1

Shrikant Mane

Yale School of Medicine

Career Start Year 1989

Number of shared co-authors 11

Motomi Mori

St Jude Children's Research Hospital.

Career Start Year 1988

Number of shared co-authors 1

Eivind Hovig

Center for Bioinformatics, University of Oslo

Career Start Year 1987

Number of shared co-authors 9

Phuong Nguyen

Hoag Memorial Hospital Presbyterian

Career Start Year 1983

Number of shared co-authors 2

Alan Ashworth

UCSF Helen Diller Family Comprehensive Cancer Center

Career Start Year 1982

Number of shared co-authors 51

Edison T Liu

USA The Jackson Laboratory Cancer Center

Career Start Year 1982

Number of shared co-authors 6

Stephen H Friend

University of Oxford

Career Start Year 1978

Number of shared co-authors 6

Gordon B Mills

Knight Cancer Institute, Oregon Health and Sciences University

Career Start Year 1976

Number of shared co-authors 18

Sean Davis

Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington

Career Start Year 1974

Number of shared co-authors 13

Judith D Goldberg

NYU Grossman School of Medicine

Career Start Year 1974

Number of shared co-authors 0

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