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Author Details

Lei Zhu
Emory University School of Medicine
2010
75
36
PMIDPaper TitleJournal TitlePublished Year
36632237Enzyme and Reactive Oxygen Species-Responsive Dual-Drug Delivery Nanocomplex for Tumor Chemo-Photodynamic Therapy.Int J Nanomedicine2023
36115156Hyaluronidase responsive second near-infrared fluorescent nanocomplex for combined HER2 blockade and chemotherapy of HER2+ breast cancer.Biomater Adv2022
35396932Advanced iron oxide nanotheranostics for multimodal and precision treatment of pancreatic ductal adenocarcinoma.Wiley Interdiscip Rev Nanomed Nanobiotechnol2022
36256454Inhibition of NADPH Oxidase-ROS Signal using Hyaluronic Acid Nanoparticles for Overcoming Radioresistance in Cancer Therapy.ACS Nano2022
34289988Targeting c-Myc to Overcome Acquired Resistance of EGFR Mutant NSCLC Cells to the Third-Generation EGFR Tyrosine Kinase Inhibitor, Osimertinib.Cancer Res2021
33905036Rictor, an essential component of mTOR complex 2, undergoes caspase-mediated cleavage during apoptosis induced by multiple stimuli.Apoptosis2021
34298765Claisened Hexafluoro Inhibits Metastatic Spreading of Amoeboid Melanoma Cells.Cancers (Basel)2021
32272454Construction and evaluation of hyaluronic acid-based copolymers as a targeted chemotherapy drug carrier for cancer therapy.Nanotechnology2020
32896851The development of a Glypican-3-specific binding peptide using <i>in vivo</i> and <i>in vitro</i> two-step phage display screening for the PET imaging of hepatocellular carcinoma.Biomater Sci2020
30824801Palladium based nanoparticles for the treatment of advanced melanoma.Sci Rep2019
31603456Glypican-3 (GPC3) targeted Fe<sub>3</sub>O<sub>4</sub> core/Au shell nanocomplex for fluorescence/MRI/photoacoustic imaging-guided tumor photothermal therapy.Biomater Sci2019
31482934Noninvasive monitoring of the development and treatment response of ischemic hindlimb by targeting matrix metalloproteinase-2 (MMP-2).Biomater Sci2019
30856555The Third-Generation EGFR Inhibitor, Osimertinib, Promotes c-FLIP Degradation, Enhancing Apoptosis Including TRAIL-Induced Apoptosis in NSCLC Cells with Activating EGFR Mutations.Transl Oncol2019
29107218Dual-targeting Wnt and uPA receptors using peptide conjugated ultra-small nanoparticle drug carriers inhibited cancer stem-cell phenotype in chemo-resistant breast cancer.Biomaterials2018
29648446Evans Blue Derivative-Functionalized Gold Nanorods for Photothermal Therapy-Enhanced Tumor Chemotherapy.ACS Appl Mater Interfaces2018
29086481Theranostic Hyaluronic Acid-Iron Micellar Nanoparticles for Magnetic-Field-Enhanced inâ¿¿vivo Cancer Chemotherapy.ChemMedChem2018
27776285Oxygen-generating hybrid nanoparticles to enhance fluorescent/photoacoustic/ultrasound imaging guided tumor photodynamic therapy.Biomaterials2017
28277675Correction to "Novel <sup>19</sup>F Activatable Probe for the Detection of Matrix Metalloprotease-2 Activity by MRI/MRS".Mol Pharm2017
29097925Preclinical Evaluation and Monitoring of the Therapeutic Response of a Dual Targeted Hyaluronic Acid Nanodrug.Contrast Media Mol Imaging2017
29114172Theranostic Probes for Cancer Imaging.Contrast Media Mol Imaging2017
28875691Construction and Evaluation of a Targeted Hyaluronic Acid Nanoparticle/Photosensitizer Complex for Cancer Photodynamic Therapy.ACS Appl Mater Interfaces2017
27876448Magnetic nanoparticles for precision oncology: theranostic magnetic iron oxide nanoparticles for image-guided and targeted cancer therapy.Nanomedicine (Lond)2017
27862961Identification of a Glypican-3-Binding Peptide for In Vivo Non-Invasive Human Hepatocellular Carcinoma Detection.Macromol Biosci2017
27916607Current status of biomarker and targeted nanoparticle development: The precision oncology approach for pancreatic cancer therapy.Cancer Lett2017
26691399Hybrid graphene/Au activatable theranostic agent for multimodalities imaging guided enhanced photothermal therapy.Biomaterials2016
26641886Stable Evans Blue Derived Exendin-4 Peptide for Type 2 Diabetes Treatment.Bioconjug Chem2016
27392290Functional long circulating single walled carbon nanotubes for fluorescent/photoacoustic imaging-guided enhanced phototherapy.Biomaterials2016
27121639Monitoring of the tumor response to nano-graphene oxide-mediated photothermal/photodynamic therapy by diffusion-weighted and BOLD MRI.Nanoscale2016
26860184Nanotubes-Embedded Indocyanine Green-Hyaluronic Acid Nanoparticles for Photoacoustic-Imaging-Guided Phototherapy.ACS Appl Mater Interfaces2016
26877782Chemical Conjugation of Evans Blue Derivative: A Strategy to Develop Long-Acting Therapeutics through Albumin Binding.Theranostics2016
26850086Novel Glypican-3-Binding Peptide for in Vivo Hepatocellular Carcinoma Fluorescent Imaging.Bioconjug Chem2016
26845246Diffusion-Weighted Magnetic Resonance Imaging for Therapy Response Monitoring and Early Treatment Prediction of Photothermal Therapy.ACS Appl Mater Interfaces2016
26234690A novel single walled carbon nanotube (SWCNT) functionalization agent facilitating in vivo combined chemo/thermo therapy.Nanoscale2015
26388178Activatable Ferritin Nanocomplex for Real-Time Monitoring of Caspase-3 Activation during Photodynamic Therapy.ACS Appl Mater Interfaces2015
26581247Role of P38 MAPK on MMP Activity in Photothrombotic Stroke Mice as Measured using an Ultrafast MMP Activatable Probe.Sci Rep2015
26681988Noninvasive Dynamic Imaging of Tumor Early Response to Nanoparticle-mediated Photothermal Therapy.Theranostics2015
23982795Comparison of three dimeric 18F-AlF-NOTA-RGD tracers.Mol Imaging Biol2014
2525062899mTc-3P4-RGD2 scintimammography in the assessment of breast lesions: comparative study with 99mTc-MIBI.PLoS One2014
25271556Novel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS.Mol Pharm2014
25402600Activatable hyaluronic acid nanoparticle as a theranostic agent for optical/photoacoustic image-guided photothermal therapy.ACS Nano2014
24465271Visualization of protease activity in vivo using an activatable photo-acoustic imaging probe based on CuS nanoparticles.Theranostics2014
24266806Rational design of matrix metalloproteinase-13 activatable probes for enhanced specificity.ACS Chem Biol2014
22588595Differentiation of reactive and tumor metastatic lymph nodes with diffusion-weighted and SPIO-enhanced MRI.Mol Imaging Biol2013
23884164Gadolinium embedded iron oxide nanoclusters as T1-T2 dual-modal MRI-visible vectors for safe and efficient siRNA delivery.Nanoscale2013
23607644Noninvasive monitoring of pulmonary fibrosis by targeting matrix metalloproteinases (MMPs).Mol Pharm2013
23683064Gold nanoparticle-based activatable probe for sensing ultralow levels of prostate-specific antigen.ACS Nano2013
23750453Development of a new thiol site-specific prosthetic group and its conjugation with [Cys(40)]-exendin-4 for in vivo targeting of insulinomas.Bioconjug Chem2013
23770832VEGF-loaded graphene oxide as theranostics for multi-modality imaging-monitored targeting therapeutic angiogenesis of ischemic muscle.Nanoscale2013
23731122Effect of injection routes on the biodistribution, clearance, and tumor uptake of carbon dots.ACS Nano2013
23471295Longitudinal bioluminescence imaging of the dynamics of Doxorubicin induced apoptosis.Theranostics2013
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Collaborators

Xiaoyuan Chen
Institute of Molecular and Cell Biology
Co-authored papers 42
Gang Niu
The First Affiliated Hospital of Xi'an Jiaotong University
Co-authored papers 33
Fan Zhang
The Second Hospital of Dalian Medical University
Co-authored papers 23
Ying Ma
National Institutes of Health
Co-authored papers 19
Seulki Lee
The Johns Hopkins University School of Medicine
Co-authored papers 17
Dale O Kiesewetter
National Institute of Biomedical Imaging and Bioengineering
Co-authored papers 14
Lixin Lang
First Hospital of Shanxi Medical University, Shanxi Medical University
Co-authored papers 9
Ning Guo
Beijing Tongren Hospital, Capital Medical University
Co-authored papers 8
Hak Soo Choi
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 4
Jinxia Guo
Co-authored papers 4
Henry S Eden
Co-authored papers 2
Ruth M O'Regan
Co-authored papers 1
Qingguo Xie
College of Life Science and Technology, Huazhong University of Science and Technology
Co-authored papers 1
Quanzheng Li
Massachusetts General Hospital
Co-authored papers 1
Orit Jacboson
Co-authored papers 1
James R Mansfield
Institute for Biodiagnostics, National Research Council Canada
Co-authored papers 1
Chenxi Wu
College of Clinical Medicine, Jining Medical University
Co-authored papers 1
Benjamin G Barwick
Emory University School of Medicine
Co-authored papers 1
Release 1.2