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Author Details

Zhong Chen
National Institute on Deafness and Other Communication Disorders
1995
112
51
PMIDPaper TitleJournal TitlePublished Year
37055579Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC).Cell Death Differ2023
37638000Oncogenic Ras and οNp63α cooperate to recruit immunosuppressive polymorphonuclear myeloid-derived suppressor cells in a mouse model of squamous cancer pathogenesis.Front Immunol2023
37055579Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC).Cell Death Differ2023
37638000Oncogenic Ras and οNp63α cooperate to recruit immunosuppressive polymorphonuclear myeloid-derived suppressor cells in a mouse model of squamous cancer pathogenesis.Front Immunol2023
35176168Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers.Mol Cancer Res2022
36119107Lipopolysaccharide sensitizes the therapeutic response of breast cancer to IAP antagonist.Front Immunol2022
35151924LncRNA Neat1 promotes the macrophage inflammatory response and acts as a therapeutic target in titanium particle-induced osteolysis.Acta Biomater2022
35176168Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers.Mol Cancer Res2022
36119107Lipopolysaccharide sensitizes the therapeutic response of breast cancer to IAP antagonist.Front Immunol2022
35151924LncRNA Neat1 promotes the macrophage inflammatory response and acts as a therapeutic target in titanium particle-induced osteolysis.Acta Biomater2022
34167951The Proteomic Landscape of Growth Factor Signaling Networks Associated with <i>FAT1</i> Mutations in Head and Neck Cancers.Cancer Res2021
34167951The Proteomic Landscape of Growth Factor Signaling Networks Associated with <i>FAT1</i> Mutations in Head and Neck Cancers.Cancer Res2021
33737574Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas.Sci Rep2021
33737574Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas.Sci Rep2021
33036368Regulation of NFκB Signalling by Ubiquitination: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma?Cancers (Basel)2020
33036368Regulation of NFκB Signalling by Ubiquitination: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma?Cancers (Basel)2020
30488488Lymphotoxin-β receptor-NIK signaling induces alternative RELB/NF-κB2 activation to promote metastatic gene expression and cell migration in head and neck cancer.Mol Carcinog2019
31624067Head and Neck Cancers Promote an Inflammatory Transcriptome through Coactivation of Classic and Alternative NF-κB Pathways.Cancer Immunol Res2019
30488488Lymphotoxin-β receptor-NIK signaling induces alternative RELB/NF-κB2 activation to promote metastatic gene expression and cell migration in head and neck cancer.Mol Carcinog2019
31266830Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV<sup>-</sup> and HPV<sup>+</sup> Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy.Clin Cancer Res2019
31266830Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV<sup>-</sup> and HPV<sup>+</sup> Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy.Clin Cancer Res2019
31624067Head and Neck Cancers Promote an Inflammatory Transcriptome through Coactivation of Classic and Alternative NF-κB Pathways.Cancer Immunol Res2019
30380422Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers.Cell Rep2018
30393585Antagonist of cIAP1/2 and XIAP enhances anti-tumor immunity when combined with radiation and PD-1 blockade in a syngeneic model of head and neck cancer.Oncoimmunology2018
30058293Current status of clinical testing for human papillomavirus in oropharyngeal squamous cell carcinoma.J Pathol Clin Res2018
29921694Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers.Cancer Res2018
29959199Targeting Notch1 and IKKα Enhanced NF-κB Activation in CD133<sup>+</sup> Skin Cancer Stem Cells.Mol Cancer Ther2018
30380422Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers.Cell Rep2018
30288354WEE1 kinase inhibition reverses G2/M cell cycle checkpoint activation to sensitize cancer cells to immunotherapy.Oncoimmunology2018
29959199Targeting Notch1 and IKKα Enhanced NF-κB Activation in CD133<sup>+</sup> Skin Cancer Stem Cells.Mol Cancer Ther2018
30058293Current status of clinical testing for human papillomavirus in oropharyngeal squamous cell carcinoma.J Pathol Clin Res2018
29921694Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers.Cancer Res2018
30393585Antagonist of cIAP1/2 and XIAP enhances anti-tumor immunity when combined with radiation and PD-1 blockade in a syngeneic model of head and neck cancer.Oncoimmunology2018
30288354WEE1 kinase inhibition reverses G2/M cell cycle checkpoint activation to sensitize cancer cells to immunotherapy.Oncoimmunology2018
28039268Therapeutic Small Molecules Target Inhibitor of Apoptosis Proteins in Cancers with Deregulation of Extrinsic and Intrinsic Cell Death Pathways.Clin Cancer Res2017
28915554Resistance to CTLA-4 checkpoint inhibition reversed through selective elimination of granulocytic myeloid cells.Oncotarget2017
28364000Anti-PD-L1 Efficacy Can Be Enhanced by Inhibition of Myeloid-Derived Suppressor Cells with a Selective Inhibitor of PI3Kδ/γ.Cancer Res2017
28039268Therapeutic Small Molecules Target Inhibitor of Apoptosis Proteins in Cancers with Deregulation of Extrinsic and Intrinsic Cell Death Pathways.Clin Cancer Res2017
28295216Genetic alterations in TRAF3 and CYLD that regulate nuclear factor κB and interferon signaling define head and neck cancer subsets harboring human papillomavirus.Cancer2017
28364000Anti-PD-L1 Efficacy Can Be Enhanced by Inhibition of Myeloid-Derived Suppressor Cells with a Selective Inhibitor of PI3Kδ/γ.Cancer Res2017
28295216Genetic alterations in TRAF3 and CYLD that regulate nuclear factor κB and interferon signaling define head and neck cancer subsets harboring human papillomavirus.Cancer2017
28915554Resistance to CTLA-4 checkpoint inhibition reversed through selective elimination of granulocytic myeloid cells.Oncotarget2017
27132513TNF-α modulates genome-wide redistribution of οNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.Oncogene2016
27132513TNF-α modulates genome-wide redistribution of οNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.Oncogene2016
27208423TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry.Biochim Biophys Acta2016
27469115SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes FADD and BIRC2.Cancer Res2016
27208423TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry.Biochim Biophys Acta2016
27469115SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes FADD and BIRC2.Cancer Res2016
24219320The PI3K/Akt/mTOR axis in head and neck cancer: functions, aberrations, cross-talk, and therapies.Oral Dis2015
25798061MEK inhibitor PD-0325901 overcomes resistance to CK2 inhibitor CX-4945 and exhibits anti-tumor activity in head and neck cancer.Int J Biol Sci2015
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Collaborators

National Institute of Deafness and Other Communication Disorders
Co-authored papers 106
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 29
The University of Hong Kong
Co-authored papers 15
Center for Cancer Research, National Cancer Institute
Co-authored papers 8
The Fifth Affiliated Hospital, Sun Yat-sen University
Co-authored papers 8
Hubei Engineering Research Center for Bio-enzyme Catalysis, Hubei University
Co-authored papers 6
State University of New York at Buffalo
Co-authored papers 4
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
Co-authored papers 4
Sackler School of Medicine, Tel Aviv University
Co-authored papers 4
Columbia University Irving Medical Center
Co-authored papers 3
National Institute on Deafness and Other Communication Disorders
Co-authored papers 3
Kresge Hearing Research Institute, University of Michigan ann arbor
Co-authored papers 3
University of North Carolina at Chapel Hill
Co-authored papers 2
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
Human Phenome Institute and Shanghai Cancer Center, Fudan University
Co-authored papers 2
University of Adelaide
Co-authored papers 2
David Geffen School of Medicine, university of california los angeles
Co-authored papers 2
University of California at Santa Cruz
Co-authored papers 2
The University of North Carolina at Chapel Hill
Co-authored papers 2
Buck Institute for Research on Aging
Co-authored papers 2
Howard Hughes Medical Institute
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Present address: Dxige Research Inc.
Co-authored papers 1
National Human Genome Research Institute
Co-authored papers 1
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 1
USA The Jackson Laboratory Cancer Center
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of California
Co-authored papers 1
All India Institute of Medical Sciences
Co-authored papers 1
Co-authored papers 1