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Author Details

Roland Beckmann
University of Munich
1985
169
66
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36259929A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia.Cancer Discov2023
37291423Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.Nat Struct Mol Biol2023
37079644The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.PLoS Biol2023
37172570SnapShot: Eukaryotic ribosome biogenesis I.Cell2023
37169754Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.Nat Commun2023
37129998Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.EMBO Rep2023
36583309Two modes of Cue2-mediated mRNA cleavage with distinct substrate recognition initiate no-go decay.Nucleic Acids Res2023
36804914Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.Mol Cell2023
36801861Structural basis for clearing of ribosome collisions by the RQT complex.Nat Commun2023
36929751Concurrent remodelling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase.Elife2023
35264790Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.Nature2022
35385737Emergence of the primordial pre-60S from the 90S pre-ribosome.Cell Rep2022
36417864Cms1 coordinates stepwise local 90S pre-ribosome assembly with timely snR83 release.Cell Rep2022
35869078Modulating co-translational protein folding by rational design and ribosome engineering.Nat Commun2022
36302773A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.Nat Commun2022
36097274Ice thickness monitoring for cryo-EM grids by interferometry imaging.Sci Rep2022
36384135IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.Immunity2022
36263816In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation.Nucleic Acids Res2022
36321656The nucleoplasmic phase of pre-40S formation prior to nuclear export.Nucleic Acids Res2022
36114226Author Correction: Modulating co-translational protein folding by rational design and ribosome engineering.Nat Commun2022
36113412Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.Mol Cell2022
35217658Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp.Nat Commun2022
33326748Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.Mol Cell2021
33876849The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation.EMBO J2021
33790014Structure of Gcn1 bound to stalled and colliding 80S ribosomes.Proc Natl Acad Sci U S A2021
33511782SAP domain forms a flexible part of DNA aperture in Ku70/80.FEBS J2021
34403461Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.Nucleic Acids Res2021
34315873A distinct assembly pathway of the human 39S late pre-mitoribosome.Nat Commun2021
33305433Architecture of the active post-translational Sec translocon.EMBO J2021
32351119Novel bioanalytical method for the characterization of the immune response directed against a bispecific F(ab) fragment.Bioanalysis2020
31988523Structure of the Bcs1 AAA-ATPase suggests an airlock-like translocation mechanism for folded proteins.Nat Struct Mol Biol2020
31858614Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.EMBO J2020
32064661Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.EMBO J2020
33208940Structural basis for the final steps of human 40S ribosome maturation.Nature2020
3294352190<i>S</i> pre-ribosome transformation into the primordial 40<i>S</i> subunit.Science2020
32744497EDF1 coordinates cellular responses to ribosome collisions.Elife2020
32687489Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.PLoS Biol2020
32601485Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.Nat Chem Biol2020
32680882Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.Science2020
32788349An ATP-dependent partner switch links flagellar C-ring assembly with gene expression.Proc Natl Acad Sci U S A2020
32668200Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.Mol Cell2020
32499615Author Correction: 3.2-ÿ-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.Nat Struct Mol Biol2020
32299921The Ccr4-Not complex monitors the translating ribosome for codon optimality.Science2020
32203490RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.Nat Struct Mol Biol2020
30609991Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.EMBO J2019
30026573Spectrum and functional validation of PSMB5 mutations in multiple myeloma.Leukemia2019
31246176Structural and mutational analysis of the ribosome-arresting human XBP1u.Elife2019
31379073Partially inserted nascent chain unzips the lateral gate of the Sec translocon.EMBO Rep2019
31378463Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.Mol Cell2019
31235950Publisher Correction: Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.Nature2019
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Collaborators

Jean-Paul Armache
Center for Eukaryotic Gene Regulation, Pennsylvania State University, University Park
Co-authored papers 14
Christian M T Spahn
Institut fur Medizinische Physik und Biophysik, Charite-Universitatsmedizin Berlin
Co-authored papers 8
Joachim Frank
Columbia University
Co-authored papers 7
Gunnar von Heijne
Stockholm University
Co-authored papers 7
Pawel A Penczek
The University of Texas, McGovern Medical School
Co-authored papers 6
Elizabeth Villa
University of California San Diego, USA Howard Hughes Medical Institute
Co-authored papers 5
James C Gumbart
Georgia Institute of Technology
Co-authored papers 4
G??nter Blobel
Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 4
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 3
Friedrich F??rster
Utrecht University
Co-authored papers 3
John Christodoulou
University of Melbourne, The Royal Children's Hospital
Co-authored papers 2
Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Narayanan Eswar
University of California at San Francisco
Co-authored papers 2
Martin Turk
Max Planck Institute of Biochemistry
Co-authored papers 2
J. Wade Harper
Harvard Medical School
Co-authored papers 1
Henning Stahlberg
Ecole Polytechnique Federale de Lausanne (EPFL), University of Lausanne
Co-authored papers 1
Albrecht von Brunn
Max-von-Pettenkofer Institute, Ludwig-Maximilians-University (LMU) Munich
Co-authored papers 1
Alexander Keith Stewart
Co-authored papers 1
Nenad Ban
Institute of Molecular Biology and Biophysics, ETH Zurich
Co-authored papers 1
Jurgen Helmers
Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 1
Denis L J Lafontaine
Universite libre de Bruxelles (ULB)
Co-authored papers 1
Christoph Driessen
Cantonal Hospital St. Gallen
Co-authored papers 1
David T Auble
University of Virginia
Co-authored papers 1
Caroline M Groft
The Rockefeller University
Co-authored papers 1
Maya Topf
Leibniz-Institut fur Virologie (LIV)
Co-authored papers 1
Dmitri I Svergun
King's College London BHF Centre for Research Excellence
Co-authored papers 1
Souad Naji
The Scripps Research Institute
Co-authored papers 1
Seth A Darst
The Rockefeller University
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Martin Beck
Max Planck Institute of Biophysics
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Pia Unverdorben
Max-Planck Institute of Biochemistry
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Release 1.2