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Author Details

Bjoern Titz
university of california los angeles
2004
73
30
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36336278Deconvolution of Systemic Pharmacokinetics Predicts Inhaled Aerosol Dosimetry of Nicotine.Eur J Pharm Sci2023
37155956Acclimation strategies of the green alga Chlorella vulgaris to different light regimes revealed by physiological and comparative proteomic analyses.J Exp Bot2023
36482696Toxicoproteomics reveals an effect of clozapine on autophagy in human liver spheroids.Toxicol Mech Methods2023
36290484Apical Medium Flow Influences the Morphology and Physiology of Human Proximal Tubular Cells in a Microphysiological System.Bioengineering (Basel)2022
36468705Shotgun Lipidomics of Rodent Tissues.J Vis Exp2022
36467029Systems biology reveals anatabine to be an NRF2 activator.Front Pharmacol2022
34089800Effects of plant alkaloids on mitochondrial bioenergetic parameters.Food Chem Toxicol2021
33825214Impact of whole-body versus nose-only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2-month cigarette smoke exposure study in the ApoE<sup>-/-</sup> mouse model.J Appl Toxicol2021
33963423A 6-month inhalation toxicology study in Apoe<sup>-/-</sup> mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.Arch Toxicol2021
32367274Evaluation of toxicity of aerosols from flavored e-liquids in Sprague-Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.Arch Toxicol2020
31975625A 6-month systems toxicology inhalation study in ApoE<sup>-/-</sup> mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke.Am J Physiol Heart Circ Physiol2020
31705857Structural, functional, and molecular impact on the cardiovascular system in ApoE<sup>-/-</sup> mice exposed to aerosol from candidate modified risk tobacco products, Carbon Heated Tobacco Product 1.2 and Tobacco Heating System 2.2, compared with cigarette smoke.Chem Biol Interact2020
33189821Ceramide ratios are affected by cigarette smoke but not heat-not-burn or e-vapor aerosols across four independent mouse studies.Life Sci2020
33204648Impact of switching to a heat-not-burn tobacco product on CYP1A2 activity.Toxicol Rep2020
32855621Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis.J Inflamm (Lond)2020
32995294Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case.Toxicol Rep2020
32780831Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.Toxicol Sci2020
32123204The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts.Sci Rep2020
32419906Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke.Comput Struct Biotechnol J2020
32339553Lipid-based biomarkers for CVD, COPD, and aging - A translational perspective.Prog Lipid Res2020
30610935Assessment of a 72-hour repeated exposure to Swedish snus extract and total particulate matter from 3R4F cigarette smoke on gingival organotypic cultures.Food Chem Toxicol2019
31494692Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESHâ¿¢ technology.Arch Toxicol2019
30763686A six-month systems toxicology inhalation/cessation study in ApoE<sup>-/-</sup> mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.Food Chem Toxicol2019
29505817Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.Food Chem Toxicol2018
30223557Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification.Int J Mol Sci2018
30849254Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.Inhal Toxicol2018
29501877Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.Food Chem Toxicol2018
29545142A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.Food Chem Toxicol2018
29654848A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.Food Chem Toxicol2018
28025120Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.Food Chem Toxicol2017
30090531Systems toxicology meta-analysis of <i>in vitro</i> assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract.Toxicol Res (Camb)2017
28882640Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints.Food Chem Toxicol2017
27027324Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis.Inhal Toxicol2016
26582801Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe-/- Mice-An Integrative Systems Toxicology Analysis.Toxicol Sci2016
26609137An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.Toxicol Sci2016
27648299JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma.Cell Discov2016
27818348Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke.Regul Toxicol Pharmacol2016
27818347Evaluation of the Tobacco Heating System 2.2. Part 7: Systems toxicological assessment of a mentholated version revealed reduced cellular and molecular exposure effects compared with mentholated and non-mentholated cigarette smoke.Regul Toxicol Pharmacol2016
27657052Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD).Int J Mol Sci2016
27273450CRAF R391W is a melanoma driver oncogene.Sci Rep2016
27268958Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice.J Proteomics2016
27499020Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer.Cell2016
27225756An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.Toxicol Sci2016
26958840Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.Nature2016
26731301Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice.Sci Data2016
25605940MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells.Proc Natl Acad Sci U S A2015
26306861Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects.J Proteomics2015
25843363A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a prototypic modified risk tobacco product.Food Chem Toxicol2015
25645078Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma.Mol Cancer2015
25811598Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1.PLoS One2015
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Collaborators

Vectura Fertin Pharma
Co-authored papers 43
Philip Morris International Research Laboratories Pte. Ltd
Co-authored papers 37
Co-authored papers 29
Universitat Basel
Co-authored papers 14
Center for the Study of Biological Complexity, Virginia Commonwealth University
Co-authored papers 10
Philip Morris International Research Laboratories Pte. Ltd
Co-authored papers 8
Vanderbilt University Medical Center
Co-authored papers 6
University of California Los Angeles (university of california los angeles)
Co-authored papers 6
SSSSGerman Cancer Research Center
Co-authored papers 5
Johns Hopkins Bayview Medical Center
Co-authored papers 4
.The Emmes Corporation
Co-authored papers 3
Co-authored papers 3
University of Washington
Co-authored papers 2
University of Southern California
Co-authored papers 2
Duke University School of Medicine
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
University of California los angeles
Co-authored papers 2
Children's Hospital of Philadelphia
Co-authored papers 2
University Clinic for Swine, University of Veterinary Medicine Vienna
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Oslo University Hospital
Co-authored papers 1
Institute of Informatics, Ludwig-Maximilians-Universitat Munchen
Co-authored papers 1
Stanford Center for Biomedical Informatics Research, Stanford University
Co-authored papers 1
University of California, Santa Cruz Genomics Institute
Co-authored papers 1
Germany Institute of Systems Biology, Shanghai University
Co-authored papers 1
University of California
Co-authored papers 1
Boehringer Ingelheim RCV GmbH & Co. KG
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Jonsson Comprehensive Cancer Center, University of California Los Angeles
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