Author details

Full Name

Uma R Chandran

Affiliation

ORCID

Career Start Year

1992

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37503050	De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression.		2023
36585450	Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis.	Nat Cancer	2023
37145994	Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice.	PLoS One	2023
36998620	Melanoma-associated repair-like Schwann cells suppress anti-tumor T-cells via 12/15-LOX/COX2-associated eicosanoid production.	Oncoimmunology	2023
36690169	Genomic glucocorticoid action in embryonic mouse neural stem cells.	Mol Cell Endocrinol	2023
34973142	Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis.	J Clin Immunol	2022
35658976	Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis.		2022
35834791	Sensory Nerves Impede the Formation of Tertiary Lymphoid Structures and Development of Protective Antimelanoma Immune Responses.	Cancer Immunology Research	2022
35953854	Risk of transmission of respiratory viruses during aerosol-generating medical procedures (AGMPs) revisited in the COVID-19 pandemic: a systematic review.	Antimicrobial Resistance and Infection Control	2022
34027841	A comparison of surgical site infections following total hip replacement and total knee replacement surgeries identified by Infection Prevention and Control and the National Surgical Quality Improvement Program in Alberta, Canada.	Infection Control and Hospital Epidemiology	2022
34525351	Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment.	Cell Reports	2021
33906066	Crohn's disease-associated ATG16L1 T300A genotype is associated with improved survival in gastric cancer.	eBioMedicine	2021
34094840	Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas.		2021
34032636	T-bet+CD27+CD21- B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants.	JCI insight	2021
33222722	The use of laboratory-identified event surveillance to classify adverse outcomes due to infection in Canadian long-term care facilities.	Infection Control and Hospital Epidemiology	2021
34450196	Microvesicles transfer mitochondria and increase mitochondrial function in brain endothelial cells.	Journal of Controlled Release	2021
34762770	HIV-1 drug resistance among individuals who seroconverted in the ASPIRE dapivirine ring trial.	Journal of the International AIDS Society	2021
32606936	ELL2 Is Required for the Growth and Survival of AR-Negative Prostate Cancer Cells.	Cancer Management and Research	2020
32298194	Differential gene expression in peripheral blood mononuclear cells from children immunized with inactivated influenza vaccine.	Hum Vaccin Immunother	2020
31554654	A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer.	Molecular Cancer Therapeutics	2020
33355274	COVID-19 screening of asymptomatic patients admitted through emergency departments in Alberta: a prospective quality-improvement study.	CMAJ open	2020
33347425	The impact of physical frailty on the response to inactivated influenza vaccine in older adults.	Aging (Albany NY)	2020
32723838	Coordinated Circulating T Follicular Helper and Activated B Cell Responses Underlie the Onset of Antibody-Mediated Rejection in Kidney Transplantation.	Journal of the American Society of Nephrology : JASN	2020
30828910	Immunogenomic correlates of response to cetuximab monotherapy in head and neck squamous cell carcinoma.	Head and Neck	2019
30590698	Gonadotrophin-mediated miRNA expression in testis at onset of puberty in rhesus monkey: predictions on regulation of thyroid hormone activity and DLK1-DIO3 locus.	Molecular Human Reproduction	2019
31014399	Multiple antigen-engineered DC vaccines with or without IFNÎ± to promote antitumor immunity in melanoma.	J Immunother Cancer	2019
30779711	IL-33-mediated IL-13 secretion by ST2+ Tregs controls inflammation after lung injury.	JCI Insight	2019
29545070	Expression of reactive species related genes is associated with patient survival in luminal B breast cancer.	Free Radic Biol Med	2018
28554804	A comparison of the sexually dimorphic dexamethasone transcriptome in mouse cerebral cortical and hypothalamic embryonic neural stem cells.	Mol Cell Endocrinol	2018
30282672	PD-L1 Mediates Dysfunction in Activated PD-1 NK Cells in Head and Neck Cancer Patients.	Cancer Immunology Research	2018
30515427	Inflammatory Mediator Expression Associated With Antibody Response Induced by Live Attenuated vs Inactivated Influenza Virus Vaccine in Children.	Open Forum Infect Dis	2018
29518696	EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer.	Neoplasia	2018
29738536	Statins impact primary embryonic mouse neural stem cell survival, cell death, and fate through distinct mechanisms.	PLoS One	2018
29633255	HDAC5-LSD1 axis regulates antineoplastic effect of natural HDAC inhibitor sulforaphane in human breast cancer cells.	International Journal of Cancer	2018
28073843	Active Estrogen Receptor-alpha Signaling in Ovarian Cancer Models and Clinical Specimens.	Clin Cancer Res	2017
28938749	The testicular transcriptome associated with spermatogonia differentiation initiated by gonadotrophin stimulation in the juvenile rhesus monkey (Macaca mulatta).	Human Reproduction	2017
28615248	The transcriptome of the opossum kidney OK proximal tubule cell line.		2017
28870994	Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia.	J Endocrinol	2017
27487266	Network ethnopharmacological evaluation of the immunomodulatory activity of Withania somnifera.	Journal of Ethnopharmacology	2017
27788220	TCGA Expedition: A Data Acquisition and Management System for TCGA Data.	PLoS One	2016
25359468	Aberrant expression of TAR DNA binding protein-43 is associated with spermatogenic disorders in men.	Reproduction, Fertility and Development	2016
27251091	Expression of Cnnm1 and Its Association with Stemness, Cell Cycle, and Differentiation in Spermatogenic Cells in Mouse Testis.	Biology of Reproduction	2016
27324437	Protein Kinase A: A Master Kinase of Granulosa Cell Differentiation.	Scientific Reports	2016
26606517	Research Resource: The Dexamethasone Transcriptome in Hypothalamic Embryonic Neural Stem Cells.	Mol Endocrinol	2016
26676749	Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNÎ³ That Induce PD-L1 Expression in Head and Neck Cancer.	Cancer Res	2016
27609629	CLABSI Risk Factors in the NICU: Potential for Prevention: A PICNIC Study.	Infection Control and Hospital Epidemiology	2016
26115441	Needs Assessment for Research Use of High-Throughput Sequencing at a Large Academic Medical Center.	PLoS One	2015
25927284	BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility - A proteomics study.	Cell Cycle	2015
25765520	Identification of a candidate stem cell in human gallbladder.	Stem Cell Research	2015
26715829	Improving Cancer Gene Expression Data Quality through a TCGA Data-Driven Evaluation of Identifier Filtering.	Cancer Informatics	2015