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Author Details

Chelsea Mayoh
Children's Cancer Institute, Lowy Cancer Research Centre
2016
62
19
PMIDPaper TitleJournal TitlePublished Year
38049564MYCN and SNRPD3 cooperate to maintain a balance of alternative splicing events that drives neuroblastoma progression.Oncogene2024
36346110Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.Int J Cancer2023
37523146High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.Cancer Res2023
36980710Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface.Cancers (Basel)2023
37013636A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.Genome Med2023
37198692Introme accurately predicts the impact of coding and noncoding variants on gene splicing, with clinical applications.Genome Biol2023
36882456Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes.Sci Rep2023
36937401<i>In vivo</i> loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma.Front Oncol2023
36932241Diagnostic classification of childhood cancer using multiscale transcriptomics.Nat Med2023
36678797Identification of Novel CSF-Derived miRNAs in Treated Paediatric Onset Spinal Muscular Atrophy: An Exploratory Study.Pharmaceutics2023
36416237NONO enhances mRNA processing of super-enhancer-associated GATA2 and HAND2 genes in neuroblastoma.EMBO Rep2023
36560881Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma.Mol Ther2023
34471258Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma.Br J Cancer2022
35851845Glutamine addiction promotes glucose oxidation in triple-negative breast cancer.Oncogene2022
35454786Suppression of the ABCA1 Cholesterol Transporter Impairs the Growth and Migration of Epithelial Ovarian Cancer.Cancers (Basel)2022
35354251Acute central nervous system toxicity during treatment of pediatric acute lymphoblastic leukemia: phenotypes, risk factors and genotypes.Haematologica2022
36505819Advances in CAR T cell immunotherapy for paediatric brain tumours.Front Oncol2022
36251721RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL).PLoS Genet2022
33567813Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia.Haematologica2022
33310889Targeted Therapy of <i>TERT</i>-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy.Clin Cancer Res2021
33852836Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.Cell Rep2021
33767157An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability.Nat Commun2021
33895784Combination efficacy of ruxolitinib with standard-of-care drugs in CRLF2-rearranged Ph-like acute lymphoblastic leukemia.Leukemia2021
33580196Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor.NPJ Precis Oncol2021
33658627A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma.Oncogene2021
33579942Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas.Nat Commun2021
34572932Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma.Cancers (Basel)2021
34683974Development of siRNA-Loaded Lipid Nanoparticles Targeting Long Non-Coding RNA LINC01257 as a Novel and Safe Therapeutic Approach for t(8;21) Pediatric Acute Myeloid Leukemia.Pharmaceutics2021
33994371Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.Clin Cancer Res2021
31325323Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia.Int J Cancer2020
31919402Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy.Br J Cancer2020
31971998Efficacy of combined CDK9/BET inhibition in preclinical models of MLL-rearranged acute leukemia.Blood Adv2020
31848452Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia.Leukemia2020
33144287Recurrent <i>SPECC1L-NTRK</i> fusions in pediatric sarcoma and brain tumors.Cold Spring Harb Mol Case Stud2020
33053751A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma.Cancers (Basel)2020
32801162Targeting TSLP-Induced Tyrosine Kinase Signaling Pathways in <i>CRLF2</i>-Rearranged Ph-like ALL.Mol Cancer Res2020
32651259Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.Cancer Res2020
32816860Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion.Cancer Res2020
32242100Reversal of glucocorticoid resistance in paediatric acute lymphoblastic leukaemia is dependent on restoring BIM expression.Br J Cancer2020
32438682Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children.Cancers (Basel)2020
32536690Examining treatment responses of diagnostic marrow in murine xenografts to predict relapse in children with acute lymphoblastic leukaemia.Br J Cancer2020
30700572Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma.Sci Transl Med2019
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
31690716The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.Nat Commun2019
32914017Crizotinib and Surgery for Long-Term Disease Control in Children and Adolescents With ALK-Positive Inflammatory Myofibroblastic Tumors.JCO Precis Oncol2019
31346162JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma.Nat Commun2019
31342168Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis.J Cancer Res Clin Oncol2019
31015346OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL.Clin Cancer Res2019
30808815Predictors of Success of Phase II Pediatric Oncology Clinical Trials.Oncologist2019
31012549Preclinical activity of the antibody-drug conjugate denintuzumab mafodotin (SGN-CD19A) against pediatric acute lymphoblastic leukemia xenografts.Pediatr Blood Cancer2019
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Collaborators

School of Clinical Medicine
Co-authored papers 29
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 28
Co-authored papers 16
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 15
Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine
Co-authored papers 13
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Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 9
Co-authored papers 8
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Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine
Co-authored papers 7
Lowy Cancer Research Centre, Children's Cancer Institute
Co-authored papers 7
Perth Children's Hospital
Co-authored papers 5
The Hospital for Sick Children
Co-authored papers 4
Co-authored papers 4
University Children's Hospital of Cologne
Co-authored papers 4
National Cancer Institute
Co-authored papers 4
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 4
Co-authored papers 3
Hospital for Sick Children
Co-authored papers 3
Co-authored papers 3
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 3
Hospital for Sick Children
Co-authored papers 3
Hospital for Sick Children
Co-authored papers 2
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Canada British Columbia Cancer Research Centre, University of British Columbia
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Institute of Pathology, University Hospital Heidelberg
Co-authored papers 2
University Medical Center Hamburg-Eppendorf
Co-authored papers 2
The Hospital for Sick Children, University of Toronto
Co-authored papers 2
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