Author details

Full Name

Deepa Hammaker

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34963199	Caspase-8 Variant G Regulates Rheumatoid Arthritis Fibroblast-Like Synoviocyte Aggressive Behavior.	ACR Open Rheumatol	2022
36266270	Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function.	Nat Commun	2022
32792961	Therapeutic Effects of Tryptanthrin and Tryptanthrin-6-Oxime in Models of Rheumatoid Arthritis.	Frontiers in Pharmacology	2020
30808624	PTPN14 phosphatase and YAP promote TGFÎ² signalling in rheumatoid synoviocytes.	Ann Rheum Dis	2019
31872186	Joint Location-Specific JAK-STAT Signaling in Rheumatoid Arthritis Fibroblast-like Synoviocytes.	ACR Open Rheumatol	2019
29194108	Epigenetics of inflammatory arthritis.	Current Opinion in Rheumatology	2018
29765031	Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes.	Nat Commun	2018
29408488	Regulation and function of apoptosis signal-regulating kinase 1 in rheumatoid arthritis.	Biochemical Pharmacology	2018
28807995	Regulation of the Cell Cycle and Inflammatory Arthritis by the Transcription Cofactor <i>LBH</i> Gene.	J Immunol	2017
27159840	LBH Gene Transcription Regulation by the Interplay of an Enhancer Risk Allele and DNA Methylation in Rheumatoid Arthritis.	Arthritis Rheumatol	2016
27282753	Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes.	Nat Commun	2016
27275015	Abnormal <i>PTPN11</i> enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammation.	JCI Insight	2016
25784649	Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.	Journal of Pharmacology and Experimental Therapeutics	2015
25707478	The Rheumatoid Arthritis Risk Gene LBH Regulates Growth in Fibroblast-like Synoviocytes.	Arthritis Rheumatol	2015
24855454	Differential regulation of anti-inflammatory genes by p38 MAP kinase and MAP kinase kinase 6.	Journal of Inflammation	2014
24400116	Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss.	PLoS ONE	2014
24470496	Phosphoinositide 3-kinase Î´ regulates migration and invasion of synoviocytes in rheumatoid arthritis.	Journal of Immunology	2014
21953132	Decreased collagen-induced arthritis severity and adaptive immunity in MKK-6-deficient mice.	Arthritis Rheum	2012
22488549	Antiinflammatory functions of p38 in mouse models of rheumatoid arthritis: advantages of targeting upstream kinases MKK-3 or MKK-6.		2012
21613249	Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis.	Rheumatology	2012
21702006	Suppression of collagen-induced arthritis in growth arrest and DNA damage-inducible protein 45Î²-deficient mice.		2011
19995751	Go upstream, young man: lessons learned from the p38 saga.	Annals of the Rheumatic Diseases	2010
19877043	Gadd45beta deficiency in rheumatoid arthritis: enhanced synovitis through JNK signaling.		2009
19427893	MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice.	Neuroscience	2009
19561096	Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression.	Journal of Immunology	2009
18713996	Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases.	Journal of Immunology	2008
17644541	Assessment of rituximab's immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results.	Annals of the Rheumatic Diseases	2008
17559674	Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes.		2007
16953659	Regulation of peripheral inflammation by spinal p38 MAP kinase in rats.	PLoS Medicine	2006
16567640	Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis.	Proceedings of the National Academy of Sciences of the United States of America	2006
17014719	PUMA-mediated apoptosis in fibroblast-like synoviocytes does not require p53.		2006
16802349	Regulation of JNK by MKK-7 in fibroblast-like synoviocytes.		2006
15778394	Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes.	Journal of Immunology	2005
15879144	Regulation of c-Jun phosphorylation by the I kappa B kinase-epsilon complex in fibroblast-like synoviocytes.	Journal of Immunology	2005
14734742	Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis.	Journal of Immunology	2004
13130464	Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK.		2003
14532158	Signal transduction networks in rheumatoid arthritis.	Annals of the Rheumatic Diseases	2003