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Author Details

Evangelos Pazarentzos
University of California san francisco
2011
20
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35419474Cell demise inhibited: Unexpected liaisons between mitochondria and Iκοα.Mol Cell Oncol2022
28287179Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution.Sci Rep2017
25982275Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3Cβ(D1067V) kinase domain mutation.Oncogene2016
27431938The transporter and permeability interactions of asymmetric dimethylarginine (ADMA) and L-arginine with the human blood-brain barrier in vitro.Brain Res2016
24769897The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis.Oncogene2015
26301689RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.Nat Med2015
25843712NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer.Cell Rep2015
25873175AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas.Cancer Cell2015
25703329Adaptive stress signaling in targeted cancer therapy resistance.Oncogene2015
25665005The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies.Nat Genet2015
25578148Stefan Grimm, 1963-2014, a tragic loss for the scientific community.Cell Death Differ2015
24522192CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex.J Cell Sci2014
25361605Iκοα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention.EMBO J2014
25001541Anticancer gene transfer for cancer gene therapy.Adv Exp Med Biol2014
24948011Mitochondrial Ca(2+) influx targets cardiolipin to disintegrate respiratory chain complex II for cell death induction.Cell Death Differ2014
23799534Dose-dependent neuroprotection of VEGF⿁⿿⿿ in Huntington's disease striatum.Mol Ther2013
22179575De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF.Cell Death Differ2012
22659130De-ubiquitinating proteases USP2a and USP2c cause apoptosis by stabilising RIP1.Biochim Biophys Acta2012
20706275Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction.Cell Death Differ2011
21183955Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction.EMBO J2011
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Gladstone Institutes
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The University of Texas MD Anderson Cancer Center
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