Author details

Full Name

Eric C Lai

Affiliation

ORCID

Career Start Year

1997

Papers

184

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37236184	Unanticipated broad phylogeny of BEN DNA-binding domains revealed by structural homology searches.		2023
37643184	Rapid evolutionary diversification of the flamenco locus across simulans clade Drosophila species.		2023
37625205	Proliferation and dissemination of killer meiotic drive loci.		2023
37289846	Essential and recurrent roles for hairpin RNAs in silencing de novo sex chromosome conflict in Drosophila simulans.		2023
37343034	Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts.	PLoS Genet	2023
37398484	The Rapidly Evolving X-linked Family Finetunes Spermatogenesis to Enhance Sperm Competition.		2023
37319212	Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution.	Science	2023
37443337	Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision.	Nat Methods	2023
37380761	microRNAs in action: biogenesis, function and regulation.		2023
36800291	Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals.	Cell Rep	2023
34759052	Molecular and genetic dissection of recursive splicing.	Life Science Alliance	2022
35512829	miR-486 is essential for muscle function and suppresses a dystrophic transcriptome.	Life Sci Alliance	2022
35801921	Regulated dicing of pre-mir-144 via reshaping of its terminal loop.	Nucleic Acids Research	2022
35281806	Regulation of the Alternative Neural Transcriptome by ELAV/Hu RNA Binding Proteins.	Frontiers in Genetics	2022
35144965	Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins.	Genes Dev	2022
34862477	Rapid evolutionary dynamics of an expanding family of meiotic drive factors and their hpRNA suppressors.	Nature Ecology and Evolution	2021
34233178	A double-negative gene regulatory circuit underlies the virgin behavioral state.	Cell Reports	2021
34007867	A comprehensive dataset of microRNA misexpression phenotypes in the eye.	Data in Brief	2021
33674589	A neural mA/Ythdf pathway is required for learning and memory in Drosophila.	Nature Communications	2021
33662357	A comprehensive in vivo screen for anti-apoptotic miRNAs indicates broad capacities for oncogenic synergy.	Developmental Biology	2021
33723258	Publisher Correction: A neural mA/Ythdf pathway is required for learning and memory in Drosophila.	Nature Communications	2021
33826609	ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing.	PLoS Genet	2021
34033644	The Exon Junction Complex and intron removal prevent re-splicing of mRNA.	PLoS Genetics	2021
33007254	Overlapping Activities of ELAV/Hu Family RNA Binding Proteins Specify the Extended Neuronal 3' UTR Landscape in Drosophila.	Molecular Cell	2020
31969356	Regulation of embryonic and adult neurogenesis by Ars2.	Development (Cambridge)	2020
32296071	XPO5 promotes primary miRNA processing independently of RanGTP.	Nature Communications	2020
32753500	Mechanism and Function of Antiviral RNA Interference in Mice.	mBio	2020
32579967	miRNAs and Neural Alternative Polyadenylation Specify the Virgin Behavioral State.	Developmental Cell	2020
31043510	Erratum: Deep experimental profiling of microRNA diversity, deployment, and evolution across the genus.	Genome Research	2019
31836703	BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila.	Nat Commun	2019
31417090	Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis.	Nat Commun	2019
31064860	Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in .	Journal of Neuroscience	2019
29233922	Deep experimental profiling of microRNA diversity, deployment, and evolution across the genus.	Genome Research	2018
30146489	DICER1 Is Essential for Self-Renewal of Human Embryonic Stem Cells.	Stem Cell Reports	2018
30086302	The hpRNA/RNAi Pathway Is Essential to Resolve Intragenomic Conflict in the Drosophila Male Germline.	Dev Cell	2018
29351846	Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals.	Mol Cell	2018
29196461	miRNA suppression of a Notch repressor directs non-neuronal fate in mechanosensory organs.	Journal of Cell Biology	2018
29632374	Short cryptic exons mediate recursive splicing in Drosophila.	Nature Structural and Molecular Biology	2018
29540498	The mir-279/996 cluster represses receptor tyrosine kinase signaling to determine cell fates in the Drosophila eye.	Development	2018
27974621	Characterization of a TUTase/RNase complex required for <i>Drosophila</i> gametogenesis.	RNA	2017
28602807	Genome-wide profiling of the 3' ends of polyadenylated RNAs.	Methods	2017
28760809	Genome-wide identification of Grainy head targets in <i>Drosophila</i> reveals regulatory interactions with the POU domain transcription factor Vvl.	Development	2017
28675155	The mA pathway facilitates sex determination in Drosophila.	Nature Communications	2017
28400435	Correction: Neural specificity of the RNA-binding protein Elav is achieved by post-transcriptional repression in non-neural tissues.	Development (Cambridge)	2017
29051389	New genes often acquire male-specific functions but rarely become essential in .	Genes and Development	2017
29191225	Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species.	Genome Biol	2017
27802174	Neural specificity of the RNA-binding protein Elav is achieved by post-transcriptional repression in non-neural tissues.	Development (Cambridge)	2016
27013671	miR-124 Regulates Diverse Aspects of Rhythmic Behavior in Drosophila.	J Neurosci	2016
26145174	Selective Suppression of the Splicing-Mediated MicroRNA Pathway by the Terminal Uridyltransferase Tailor.	Mol Cell	2015
25544562	Adaptive regulation of testis gene expression and control of male fertility by the Drosophila hairpin RNA pathway. [Corrected].	Mol Cell	2015