|
| 38042508 | Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing. | Neurobiol Dis | 2024 |
| 36657633 | BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPT<sup>P301S</sup> mouse model of tauopathy. | Neurosci Lett | 2023 |
| 37662269 | Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice. | bioRxiv | 2023 |
| 37749581 | miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy. | J Neuroinflammation | 2023 |
| 37745468 | Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease. | bioRxiv | 2023 |
| 37886598 | Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease. | Res Sq | 2023 |
| 38037091 | Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy. | J Neuroinflammation | 2023 |
| 37424750 | Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice. | Front Behav Neurosci | 2023 |
| 37230765 | Effect of Aging and a Dual Orexin Receptor Antagonist on Sleep Architecture and Non-REM Oscillations Including an REM Behavior Disorder Phenotype in the PS19 Mouse Model of Tauopathy. | J Neurosci | 2023 |
| 36448627 | Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease. | Alzheimers Dement | 2023 |
| 36599066 | Moving the Needle on Alzheimer's Disease with an Anti-Oligomer Antibody. | N Engl J Med | 2023 |
| 36289639 | Postnatal Conditional Deletion of <i>Bcl11b</i> in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington's Disease. | Biomedicines | 2022 |
| 36429060 | Intranasal Peptide Therapeutics: A Promising Avenue for Overcoming the Challenges of Traditional CNS Drug Development. | Cells | 2022 |
| 36534642 | A novel Oprm1-Cre mouse maintains endogenous expression, function and enables detailed molecular characterization of μ-opioid receptor cells. | PLoS One | 2022 |
| 36497141 | Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females. | Cells | 2022 |
| 36002854 | Microglial TYROBP/DAP12 in Alzheimer's disease: Transduction of physiological and pathological signals across TREM2. | Mol Neurodegener | 2022 |
| 33238137 | Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease. | Neuron | 2021 |
| 33857404 | The dystonia gene THAP1 controls DNA double-strand break repair choice. | Mol Cell | 2021 |
| 33523961 | Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets. | Sci Adv | 2021 |
| 34924992 | Transcriptomic Changes Highly Similar to Alzheimer's Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging. | Front Aging Neurosci | 2021 |
| 34672987 | Dystonia-specific mutations in THAP1 alter transcription of genes associated with neurodevelopment and myelin. | Am J Hum Genet | 2021 |
| 34609283 | Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation. | Elife | 2021 |
| 34403156 | Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms. | Mov Disord | 2021 |
| 33988687 | Alzheimer mutant speeds APP transport. | J Exp Med | 2021 |
| 34081916 | Neuronal intranuclear inclusion disease: Polyglycine protein is the culprit. | Neuron | 2021 |
| 34024231 | Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels. | Autophagy | 2021 |
| 33314529 | Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice. | Alzheimers Dement | 2021 |
| 33458877 | Striatal Dopamine Induced ERK Phosphorylation Is Altered in Mouse Models of Monogenic Dystonia. | Mov Disord | 2021 |
| 33369735 | Abnormal cerebellar function and tremor in a mouse model for non-manifesting partially penetrant dystonia type 6. | J Physiol | 2021 |
| 31267641 | Neurobehavioral effects of neonatal opioid exposure in mice: Influence of the OPRM1 SNP. | Addict Biol | 2020 |
| 31924226 | VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice. | Mol Neurodegener | 2020 |
| 33149216 | Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons. | Nat Commun | 2020 |
| 32770063 | Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. | Nat Commun | 2020 |
| 32668255 | Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. | Cell Rep | 2020 |
| 32666270 | miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease. | Acta Neuropathol | 2020 |
| 30283031 | Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau. | Mol Psychiatry | 2019 |
| 31669362 | A Novel Transgenic Mouse Model to Investigate the Cell-Autonomous Effects of torsinA(οE) Expression in Striatal Output Neurons. | Neuroscience | 2019 |
| 31855627 | Clarifying the Potential Role of Microbes in Alzheimer's Disease. | Neuron | 2019 |
| 31529216 | Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington's Disease: Insights from In Vitro and In Vivo Models. | Neurotherapeutics | 2019 |
| 31320448 | Diverse Mechanisms Lead to Common Dysfunction of Striatal Cholinergic Interneurons in Distinct Genetic Mouse Models of Dystonia. | J Neurosci | 2019 |
| 31541002 | Nuclear Receptor Nr4a1 Regulates Striatal Striosome Development and Dopamine D<sub>1</sub> Receptor Signaling. | eNeuro | 2019 |
| 31141716 | Relationship of traumatic brain injury to chronic mental health problems and dementia in military veterans. | Neurosci Lett | 2019 |
| 30464330 | Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden. | Mol Psychiatry | 2019 |
| 30366018 | Efficient RNA interference-based knockdown of mutant torsinA reveals reversibility of PERK-eIF2α pathway dysregulation in DYT1 transgenic rats in vivo. | Brain Res | 2019 |
| 30283032 | Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden. | Mol Psychiatry | 2019 |
| 29289717 | Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain. | Neuroscience | 2018 |
| 29945882 | An atlas of chromatin accessibility in the adult human brain. | Genome Res | 2018 |
| 29937276 | Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus. | Neuron | 2018 |
| 30204156 | The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. | Sci Data | 2018 |
| 29364887 | Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions. | PLoS Genet | 2018 |