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Author Details

Iswar K Hariharan
University of California berkeley
1981
83
42
PMIDPaper TitleJournal TitlePublished Year
36993542Coordinated growth of linked epithelia is mediated by the Hippo pathway.bioRxiv2023
37577631The cell adhesion molecule Echinoid promotes tissue survival and separately restricts tissue overgrowth in <i>Drosophila</i> imaginal discs.bioRxiv2023
34872971Imaginal Disc Regeneration: Something Old, Something New.Cold Spring Harb Perspect Biol2022
35820420Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs.Curr Biol2022
33749594Single-cell transcriptomics of the <i>Drosophila</i> wing disc reveals instructive epithelium-to-myoblast interactions.Elife2021
33629503Membrane potential regulates Hedgehog signalling in the Drosophila wing imaginal disc.EMBO Rep2021
32490812Damage-responsive, maturity-silenced enhancers regulate multiple genes that direct regeneration in <i>Drosophila</i>.Elife2020
33298454The Hippo pathway coactivator Yorkie can reprogram cell fates and create compartment-boundary-like interactions at clone margins.Sci Adv2020
31246542Harnessing epithelial homeostatic mechanisms to fight cancer.Mol Biol Cell2019
29372681CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating <i>Drosophila</i> imaginal discs.Elife2018
30515478The BMP2/4 ortholog Dpp can function as an inter-organ signal that regulates developmental timing.Life Sci Alliance2018
28950097Ras Brakes for Hippo.Dev Cell2017
28376317Imaginal disc regeneration takes flight.Curr Opin Cell Biol2017
26840050Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs.Elife2016
27452696Plexins function in epithelial repair in both Drosophila and zebrafish.Nat Commun2016
27486229Size regulation blossoms in Kobe.Development2016
26984059Persistence of RNAi-Mediated Knockdown in Drosophila Complicates Mosaic Analysis Yet Enables Highly Sensitive Lineage Tracing.Genetics2016
25605786CoinFLP: a system for efficient mosaic screening and for visualizing clonal boundaries in Drosophila.Development2015
26267393Organ Size Control: Lessons from Drosophila.Dev Cell2015
26216720Indeterminate Growth: Could It Represent the Ancestral Condition?Cold Spring Harb Perspect Biol2015
25812520Energy stress tames the Hippo pathway.Nat Cell Biol2015
25107277The Drosophila F-box protein Fbxl7 binds to the protocadherin fat and regulates Dachs localization and Hippo signaling.Elife2014
23459941The Drosophila ortholog of MLL3 and MLL4, trithorax related, functions as a negative regulator of tissue growth.Mol Cell Biol2013
23785055TIE-DYE: a combinatorial marking system to visualize and genetically manipulate clones during development in Drosophila melanogaster.Development2013
22683826Differences in levels of the transmembrane protein Crumbs can influence cell survival at clonal boundaries.Dev Biol2012
22934642Regeneration and transdetermination in Drosophila imaginal discs.Annu Rev Genet2012
22745287The hippo pathway.Cold Spring Harb Perspect Biol2012
22715466How growth abnormalities delay "puberty" in Drosophila.Sci Signal2012
21926302Identification and characterization of genes required for compensatory growth in Drosophila.Genetics2011
20346676Inactivation of both Foxo and reaper promotes long-term adult neurogenesis in Drosophila.Curr Biol2010
21085633A buoyancy-based screen of Drosophila larvae for fat-storage mutants reveals a role for Sir2 in coupling fat storage to nutrient availability.PLoS Genet2010
20189388Retinoids regulate a developmental checkpoint for tissue regeneration in Drosophila.Curr Biol2010
20212086The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila.Mol Cell Biol2010
19531351Regenerative growth in Drosophila imaginal discs is regulated by Wingless and Myc.Dev Cell2009
18299344FOXO-regulated transcription restricts overgrowth of Tsc mutant organs.J Cell Biol2008
17398096Capicua regulates cell proliferation downstream of the receptor tyrosine kinase/ras signaling pathway.Curr Biol2007
18820468Mutation of the gene encoding the ubiquitin activating enzyme ubal causes tissue overgrowth in Drosophila.Fly (Austin)2007
17258190The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling.Dev Biol2007
16533943The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death.J Cell Biol2006
17114577Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons.Genes Dev2006
17174912Growth regulation: a beginning for the hippo pathway.Curr Biol2006
16872256Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila.Annu Rev Genet2006
15737926Ras and Rap: are former enemies now friends?Dev Cell2005
16143599Mutations in the Drosophila orthologs of the F-actin capping protein alpha- and beta-subunits cause actin accumulation and subsequent retinal degeneration.Genetics2005
16256744Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth.Dev Cell2005
15913747Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer.Gynecol Oncol2005
16098825Melting fat away in flies.Cell Metab2005
15182669The Drosophila F box protein archipelago regulates dMyc protein levels in vivo.Curr Biol2004
12802034Yeast, flies, worms, and fish in the study of human disease.N Engl J Med2003
12941274The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis.Cell2003
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Collaborators

The University of Florida
Co-authored papers 4
The Francis Crick Institute
Co-authored papers 4
Precision Medicine Network Inc.
Co-authored papers 2
Broad Institute of Harvard and MIT
Co-authored papers 2
Thomas Jefferson University
Co-authored papers 2
University Hospital Wishaw
Co-authored papers 2
Center for Computational Biology, University of California berkeley
Co-authored papers 2
National Center for Genome Resources
Co-authored papers 2
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Howard Hughes Medical Institute
Co-authored papers 1
Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra)
Co-authored papers 1
Harry Perkins Institute of Medical Research
Co-authored papers 1
Monash University at Cabrini Health
Co-authored papers 1
Institute of Infectious Diseases and Vaccinology, National Health Research Institutes
Co-authored papers 1
Co-authored papers 1
Lawrence Berkeley National Laboratory
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Global Health Institute, Ecole Polytechnique Federale de Lausanne (EPFL)
Co-authored papers 1
Stanford University
Co-authored papers 1
University of California berkeley
Co-authored papers 1
University of Leeds
Co-authored papers 1
University of British Columbia
Co-authored papers 1
Rockefeller University
Co-authored papers 1
College of Veterinary Medicine, Sichuan Agricultural University
Co-authored papers 1
National Institutes of Health (NIH)
Co-authored papers 1
Co-authored papers 1
Lawrence Berkeley National Laboratory
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1