|
| 36868853 | Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane. | J Neurosci | 2023 |
| 37711184 | Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis. | Comput Struct Biotechnol J | 2023 |
| 37609337 | Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates. | bioRxiv | 2023 |
| 36988826 | Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance. | Clin Pharmacokinet | 2023 |
| 36690119 | Epithelial and microbial determinants of colonic drug distribution. | Eur J Pharm Sci | 2023 |
| 34435745 | Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity - a non-randomized three-armed controlled trial. | Clin Transl Sci | 2022 |
| 35806468 | Hepatic Expression of the Na<sup>+</sup>-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation. | Int J Mol Sci | 2022 |
| 35773367 | Professor Margareta Hammarlund-Udenaes - Humbled Scientist Shaping Modern Neuropharmacokinetics. | Pharm Res | 2022 |
| 35648149 | Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range. | Eur J Clin Pharmacol | 2022 |
| 35404513 | Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity. | Br J Clin Pharmacol | 2022 |
| 36244560 | The impact of inflammation on the expression of drug transporters and metabolic enzymes in colonic tissue from ulcerative colitis patients. | Int J Pharm | 2022 |
| 35998570 | Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat. | ACS Nano | 2022 |
| 36037309 | Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity. | Clin Transl Sci | 2022 |
| 36087256 | Apoptosis Detection by Quantification of Cell Debris in Bright-Field Microscopy Images. | Methods Mol Biol | 2022 |
| 36189884 | Monitoring drug-target interactions through target engagement-mediated amplification on arrays and in situ. | Nucleic Acids Res | 2022 |
| 34891119 | Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration. | Biomed Pharmacother | 2022 |
| 35158408 | Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity. | Clin Pharmacol Ther | 2022 |
| 35089508 | High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3. | Pharm Res | 2022 |
| 32970864 | Proteomics-Informed Prediction of Rosuvastatin Plasma Profiles in Patients With a Wide Range of Body Weight. | Clin Pharmacol Ther | 2021 |
| 33739838 | Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes. | Mol Pharm | 2021 |
| 33610694 | Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network. | Adv Drug Deliv Rev | 2021 |
| 34887943 | Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer. | Ther Adv Med Oncol | 2021 |
| 34746700 | Conditions for maintenance of hepatocyte differentiation and function in 3D cultures. | iScience | 2021 |
| 34321656 | Getting a grip with kirigami. | Nat Mater | 2021 |
| 34233735 | Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis. | J Exp Clin Cancer Res | 2021 |
| 33452735 | Hepatocyte size fractionation allows dissection of human liver zonation. | J Cell Physiol | 2021 |
| 33159915 | Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease. | J Pharm Sci | 2021 |
| 33007277 | Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1. | J Pharm Sci | 2021 |
| 32161261 | Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy. | Nat Commun | 2020 |
| 31937946 | A new opening for orally taken peptide drugs. | Nat Biomed Eng | 2020 |
| 31685482 | A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity. | Drug Metab Dispos | 2020 |
| 32743945 | The Critical Role of Passive Permeability in Designing Successful Drugs. | ChemMedChem | 2020 |
| 32243721 | Cell-type-resolved proteomic analysis of the human liver. | Liver Int | 2020 |
| 32344570 | Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions. | Pharmaceutics | 2020 |
| 30560367 | A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes. | Arch Toxicol | 2019 |
| 33575562 | Global variability analysis of mRNA and protein concentrations across and within human tissues. | NAR Genom Bioinform | 2019 |
| 31701258 | A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f<sub>u,cell</sub>). | Pharm Res | 2019 |
| 31214810 | Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies. | AAPS J | 2019 |
| 31175671 | Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper. | Clin Pharmacol Ther | 2019 |
| 31001971 | Image-Based Quantification of Cell Debris as a Measure of Apoptosis. | Anal Chem | 2019 |
| 30971754 | Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations. | Sci Rep | 2019 |
| 30336047 | Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking. | J Proteome Res | 2019 |
| 29235598 | The stimulation of GLP-1 secretion and delivery of GLP-1 agonists via nanostructured lipid carriers. | Nanoscale | 2018 |
| 30126863 | CRISPR-Cas9: A New Addition to the Drug Metabolism and Disposition Tool Box. | Drug Metab Dispos | 2018 |
| 30442810 | Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation. | Science | 2018 |
| 29386590 | Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound. | Sci Rep | 2018 |
| 29709195 | Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids. | Mol Pharm | 2018 |
| 29301589 | Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells. | Genome Med | 2018 |
| 29343608 | Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates. | Drug Metab Dispos | 2018 |
| 28709005 | Retraction Notice to: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule. | Cell | 2017 |