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Author Details

William H Fleming
Oregon Health & Science University
1947
144
40
PMIDPaper TitleJournal TitlePublished Year
38062031Clonal hematopoiesis related TET2 loss-of-function impedes IL1β-mediated epigenetic reprogramming in hematopoietic stem and progenitor cells.Nat Commun2023
32997960MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia.Cell Stem Cell2021
34632284Relations between Description and Experimentation in the Metacontingency Enterprise: An Interbehavioral Analysis.Perspect Behav Sci2021
32054685Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.J Biol Chem2020
30242244LMTK3 is essential for oncogenic KIT expression in KIT-mutant GIST and melanoma.Oncogene2019
29190822The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model.PLoS One2017
25738896The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice.Radiat Res2015
26119982The Corepressor Rcor1 Is Essential for Normal Myeloerythroid Lineage Differentiation.Stem Cells2015
25636760Intestinal microbiota-derived metabolomic blood plasma markers for prior radiation injury.Int J Radiat Oncol Biol Phys2015
24161922HCMV infection of humanized mice after transplantation of G-CSF-mobilized peripheral blood stem cells from HCMV-seropositive donors.Biol Blood Marrow Transplant2014
24637335Functional integration of acute myeloid leukemia into the vascular niche.Leukemia2014
24652990Corepressor Rcor1 is essential for murine erythropoiesis.Blood2014
23087056Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening.Cancer Res2013
23939266Endothelial cells mitigate DNA damage and promote the regeneration of hematopoietic stem cells after radiation injury.Stem Cell Res2013
22658276Multiplex high-throughput gene mutation analysis in acute myeloid leukemia.Hum Pathol2012
22241980A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection.PLoS Pathog2011
19720572Endothelial cells mediate the regeneration of hematopoietic stem cells.Stem Cell Res2010
20833379Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model.Cell Host Microbe2010
20826722Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.Blood2010
19251665Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds.Proc Natl Acad Sci U S A2009
26829828Dr. Fleming Becomes President: Music's Loss Is Medicine's Gain.Tex Med2009
19759357BMP4 regulates the hematopoietic stem cell niche.Blood2009
18625744Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma.J Exp Med2008
19043576Hematopoietic stem cells contribute to lymphatic endothelium.PLoS One2008
16216560In vivo genetic selection of renal proximal tubules.Mol Ther2006
16920790Myeloid lineage progenitors give rise to vascular endothelium.Proc Natl Acad Sci U S A2006
16606845Bone marrow-derived cells fuse with normal and transformed intestinal stem cells.Proc Natl Acad Sci U S A2006
16690777Mouse models of hematopoietic engraftment: limitations of transgenic green fluorescent protein strains and a high-performance liquid chromatography approach to analysis of erythroid chimerism.Stem Cells2006
15528318The hereditary hemochromatosis protein, HFE, lowers intracellular iron levels independently of transferrin receptor 1 in TRVb cells.Blood2005
15849171Donor marker infidelity in transgenic hematopoietic stem cells.Stem Cells2005
12958072Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells.Blood2004
15548607Transplanted human bone marrow contributes to vascular endothelium.Proc Natl Acad Sci U S A2004
15195088Myelomonocytic cells are sufficient for therapeutic cell fusion in liver.Nat Med2004
15126319PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors.Blood2004
14585360Converging roads: evidence for an adult hemangioblast.Exp Hematol2003
14585378Activation of the G-CSF and Flt-3 receptors protects hematopoietic stem cells from lethal irradiation.Exp Hematol2003
12209349Toxic megacolon: a life-threatening complication of high-dose therapy and autologous stem cell transplantation among patients with AL amyloidosis.Bone Marrow Transplant2002
12160847Adult blood vessels restore host hematopoiesis following lethal irradiation.Exp Hematol2002
11495700Progenipoietin-1: a multifunctional agonist of the granulocyte colony-stimulating factor receptor and fetal liver tyrosine kinase-3 is a potent mobilizer of hematopoietic stem cells.Exp Hematol2001
10477746In vivo selection of wild-type hematopoietic stem cells in a murine model of Fanconi anemia.Blood1999
10232736Administration of daniplestim and granulocyte colony-stimulating factor for the mobilization of hematopoietic progenitor cells in nonhuman primates.Biol Blood Marrow Transplant1999
9827901In utero transplantation of human fetal haemopoietic cells in NOD/SCID mice.Br J Haematol1998
9894561MHC class II gene silencing in trophoblast cells is caused by inhibition of CIITA expression.Am J Reprod Immunol1998
9516161Lymphoid reconstitution after autologous PBSC transplantation with FACS-sorted CD34+ hematopoietic progenitors.Blood1998
9376606Sustained multilineage engraftment of allogeneic hematopoietic stem cells in NOD/SCID mice after in utero transplantation.Blood1997
8605339Engraftment potential of different sources of human hematopoietic progenitor cells in BNX Mice.Blood1996
7544640CD34+ progenitor cells from asymptomatic patients are not a major reservoir for human immunodeficiency virus-1.Blood1995
7847950Myocardial protection for acquired heart disease surgery: results of a national survey.Ann Thorac Surg1995
7776682Pulmonary resection for invasive Aspergillus infections in immunocompromised patients.J Thorac Cardiovasc Surg1995
7911343Rapid and sustained hematopoietic recovery in lethally irradiated mice transplanted with purified Thy-1.1lo Lin-Sca-1+ hematopoietic stem cells.Blood1994
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Collaborators

Devorah C Goldman
Oregon Health & Science University
Co-authored papers 16
John D Kugler
University of Nebraska Medical Center/Children's Hospital & Medical Center
Co-authored papers 15
John P Cheatham
Nationwide Children's Hospital
Co-authored papers 9
Larry A Latson
The Pediatric Heart Institute, Joe DiMaggio Children's Hospital
Co-authored papers 6
Guang Fan
Oregon Health and Science University
Co-authored papers 5
Melissa H Wong
Oregon Health & Science University
Co-authored papers 4
Jeffrey W Tyner
Oregon Health & Science University School of Medicine
Co-authored papers 4
Daniel N Streblow
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 3
Craig N Kreklywich
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 3
Jay A Nelson
Oregon Health and Science University
Co-authored papers 3
Christopher L Corless
Oregon Health & Science University
Co-authored papers 3
Huilan Yao
Vollum Institute, Oregon Health & Science University
Co-authored papers 2
Gail Mandel
Vollum Institute, Oregon Health and Science University
Co-authored papers 2
Jennifer Dunlap
Oregon Health & Science University
Co-authored papers 2
Marc M Loriaux
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Grover C Bagby
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 2
Yassmine Akkari
Association for Molecular Pathology
Co-authored papers 2
Brian J Druker
Oregon Health & Science University
Co-authored papers 1
Stephen E Spurgeon
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 1
Tamilla Nechiporuk
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 1
Michael W Deininger
University of Utah Huntsman Cancer Institute
Co-authored papers 1
Alan D D'Andrea
Dana-Farber Cancer Institute
Co-authored papers 1
Jason Gotlib
Stanford University School of Medicine
Co-authored papers 1
Anupriya Agarwal
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Francois Villinger
Co-authored papers 1
Stephen T Oh
Washington University School of Medicine
Co-authored papers 1
Sunita Kawane
Clinical & Translational Research Institute, Oregon Health and Science University
Co-authored papers 1
Brandon Hayes-Lattin
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Stuart H Orkin
Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School
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Release 1.2