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Author Details

Richard R Meehan
Institute of Genetics and Molecular Medicine, University of Edinburgh
1984
121
52
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33306983Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis.Cell Metab2021
33951466Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis.Cell Metab2021
31389294Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylation.Epigenetics2020
33409477A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis.iScience2020
32585002Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes.Nucleic Acids Res2020
32131813Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells.BMC Biol2020
31612522Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos.EMBO J2019
31722211DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency.Cell Rep2019
29224170Affinity-Based Enrichment Techniques for the Genome-Wide Analysis of 5-Hydroxymethylcytosine.Methods Mol Biol2018
29941872A reassessment of DNA-immunoprecipitation-based genomic profiling.Nat Methods2018
30458140A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice.Dev Cell2018
29636086Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations.Genome Biol2018
29542689Corrigendum: Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.Nature2018
29786565Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells.Philos Trans R Soc Lond B Biol Sci2018
29505975DNA methylation as a genomic marker of exposure to chemical and environmental agents.Curr Opin Chem Biol2018
261264475-Hydroxymethylcytosine Profiling in Human DNA.Methods Mol Biol2017
28386604Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism.Sci Immunol2017
28300471Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer.Epigenetics2017
28351383Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions.Genome Biol2017
29707653Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD.Wellcome Open Res2017
29130343Defining baseline epigenetic landscapes in the rat liver.Epigenomics2017
28958911Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.Regul Toxicol Pharmacol2017
29167195Shoring up DNA methylation and H3K27me3 domain demarcation at developmental genes.EMBO J2017
28700576Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.Nature2017
28806172Mobilization of LINE-1 retrotransposons is restricted by <i>Tex19.1</i> in mouse embryonic stem cells.Elife2017
28546579Corrigendum: SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome.Nat Genet2017
27936926The application of genome-wide 5-hydroxymethylcytosine studies in cancer research.Epigenomics2017
28067909SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome.Nat Genet2017
273463505-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4(+) T Cells.Cell Rep2016
27392147A Mutant Form of MeCP2 Protein Associated with Human Rett Syndrome Cannot Be Displaced from Methylated DNA by Notch in Xenopus Embryos.Mol Cell2016
27197233Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.Cancer Res2016
25358258MBD4 interacts with and recruits USP7 to heterochromatic foci.J Cell Biochem2015
26491684Lsh Is Essential for Maintaining Global DNA Methylation Levels in Amphibia and Fish and Interacts Directly with Dnmt1.Biomed Res Int2015
26134581Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute.Toxicology2015
25985418DNA immunoprecipitation semiconductor sequencing (DIP-SC-seq) as a rapid method to generate genome wide epigenetic signatures.Sci Rep2015
25648825Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems.Genome Biol2015
24001620Epigenetic profiles as defined signatures of xenobiotic exposure.Mutat Res Genet Toxicol Environ Mutagen2014
25473422Modules, networks and systems medicine for understanding disease and aiding diagnosis.Genome Med2014
25546306Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4(+) T cells tolerized by peptide immunotherapy.Elife2014
25225576Dynamic changes in DNA modification states during late gestation male germ line development in the rat.Epigenetics Chromatin2014
24690595Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.Toxicol Sci2014
24277643DNA methylation reprogramming in cancer: does it act by re-configuring the binding landscape of Polycomb repressive complexes?Bioessays2014
24045705Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline.Cell Mol Life Sci2014
24162994Hydroxymethylated DNA immunoprecipitation (hmeDIP).Methods Mol Biol2014
24162993Investigating 5-hydroxymethylcytosine (5hmC): the state of the art.Methods Mol Biol2014
23091169Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion.Toxicol Sci2013
242838805-hydroxymethylcytosine profiling as an indicator of cellular state.Epigenomics2013
24367978Lsh regulates LTR retrotransposon repression independently of Dnmt3b function.Genome Biol2013
24270890Senescent cells harbour features of the cancer epigenome.Nat Cell Biol2013
24251074LINE-1 activation and epigenetic silencing of suppressor genes in cancer: Causally related events?Mob Genet Elements2013
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Collaborators

John P Thomson
MRC Institute of Genetics and Cancer, University of Edinburgh
Co-authored papers 30
Duncan Sproul
Institute of Genetics and Cancer, University of Edinburgh
Co-authored papers 9
John M Greally
Co-authored papers 3
Nicholas D Hastie
Co-authored papers 3
Morad Ansari
Western General Hospital
Co-authored papers 2
Victor Koteliansky
Co-authored papers 2
Cynthia C Morton
Co-authored papers 2
John Kenneth Baillie
Roslin Institute, University of Edinburgh
Co-authored papers 2
Kaitlin E Samocha
Co-authored papers 2
Daniel G MacArthur
Broad Institute of MIT and Harvard
Co-authored papers 2
David R FitzPatrick
Institute of Genetics and Cancer, The University of Edinburgh MRC Human Genetics Unit
Co-authored papers 2
Steven D Chernausek
Co-authored papers 2
Jill Clayton-Smith
Institute of Human Development, University of Manchester
Co-authored papers 2
Janet E Hall
2Clinical Research Branch, National Institute of Environmental Health Sciences
Co-authored papers 2
Jeanie B Tryggestad
Co-authored papers 2
Peter D Adams
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Claire Brock
Beatson Institute for Cancer Research and University of Glasgow
Co-authored papers 2
Masako Suzuki
Co-authored papers 2
Roman L Bogorad
Co-authored papers 2
Monkol Lek
Co-authored papers 2
Philippe Couttet
Co-authored papers 2
Kathleen A Williamson
Institute of Genetics and Cancer, The University of Edinburgh MRC Human Genetics Unit
Co-authored papers 2
Angela E Lin
MassGeneral Hospital for Children
Co-authored papers 2
James F Gusella
Co-authored papers 2
Tony McBryan
The Beatson Institute
Co-authored papers 2
Nicholas Katsanis
Northwestern University
Co-authored papers 2
Paola Picotti
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Jörg Hackermüller
Co-authored papers 1
Gail E Herman
12306The Ohio State University
Co-authored papers 1
Cyrus Cooper
Co-authored papers 1
Release 1.2